66 studies found for:    Medivation
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Rank Status Study
21 Completed A Safety and Efficacy Study of Dimebon in Patients With Huntington Disease
Condition: Huntington Disease
Interventions: Drug: Dimebon;   Other: Placebo
22 Completed Determine the Effect of MDV3100 on the Androgen Signaling Pathway in Correlation With the Anti-tumor Effects of MDV3100 to Identify Potential Predictors of Response or Resistance to Therapy
Condition: Metastatic Progressive Castration-resistant Prostate Cancer
Intervention: Drug: MDV3100
23 Active, not recruiting
Has Results
A Safety and Efficacy Study of Oral MDV3100 in Chemotherapy-Naive Patients With Progressive Metastatic Prostate Cancer
Condition: Prostate Cancer
Interventions: Drug: Enzalutamide;   Drug: Placebo
24 Approved for marketing Provide Expanded Access to MDV3100 and Monitor Its Safety in Patients With Progressive Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy
Condition: Metastatic Castration-Resistant Prostate Cancer
Intervention: Drug: MDV3100
25 Recruiting A Study to Evaluate Enzalutamide After Abiraterone in Metastatic Castration-Resistant Prostate Cancer
Condition: Metastatic Castration-Resistant Prostate Cancer
Intervention: Drug: Enzalutamide
26 Recruiting A Study to Assess the Efficacy and Safety of Enzalutamide With Trastuzumab in Subjects With Human Epidermal Growth Factor Receptor 2 Positive (HER2+), Androgen Receptor Positive (AR+) and Estrogen Receptor Negative (ER-) Metastatic or Locally Advanced Breast Cancer
Conditions: Advanced Breast Cancer;   Human Epidermal Growth Factor Receptor 2 (HER2);   HER2 Amplified
Interventions: Drug: enzalutamide;   Drug: trastuzumab
27 Active, not recruiting A Study to Determine Safety and Tolerability of Enzalutamide (MDV3100) in Combination With Abiraterone Acetate in Bone Metastatic Castration-Resistant Prostate Cancer Patients
Condition: Metastatic Castration-Resistant Prostate Cancer
Interventions: Drug: enzalutamide;   Drug: abiraterone acetate;   Drug: prednisone
28 Completed Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [Pf-01913539] In Subjects With Hepatic Impairment And Normal Hepatic Function
Condition: Hepatic Failure
Intervention: Drug: Dimebon
29 Completed A Phase 1 Study To Evaluate The Effect Of Dimebon On The Pharmacokinetics Of Dextromethorphan
Conditions: Huntington Disease;   Alzheimer Disease
Interventions: Drug: Dextromethorphan;   Drug: Dimebon + Dextromethorphan
30 Active, not recruiting A Study to Assess the Safety of Continued Administration of MDV3100 in Subjects With Prostate Cancer Who Showed Benefit From Prior Exposure to MDV3100
Condition: Castration-Resistant Prostate Cancer (CRPC)
Intervention: Drug: MDV3100
31 Not yet recruiting Randomized Salvage Radiation Therapy Plus Enzalutamide Post Prostatectomy
Condition: Adenocarcinoma of the Prostate
Interventions: Drug: Enzalutamide;   Radiation: SRT
32 Completed A Phase 1, Randomized, Open-Label, Two-Way Crossover Study To Evaluate The Steady-State Effect Of Dimebon (PF 01913539) On The Single-Dose Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy Subjects
Conditions: Alzheimer's Disease;   Huntington's Disease
Interventions: Drug: Warfarin;   Drug: Dimebon
33 Completed
Has Results
A Phase 3 Study To Evaluate The Safety And Tolerability Of Dimebon Patients With Mild To Moderate Alzheimer's Disease
Condition: Alzheimer's Disease
Interventions: Drug: Dimebon;   Drug: Placebo
34 Terminated
Has Results
An Extension To The B1451027 Protocol To Evaluate The Long Term Safety And Tolerability Of Dimebon In Patients With Alzheimer's Disease
Condition: Alzheimer's Disease
Intervention: Drug: Dimebon
35 Completed Drug-drug Interaction Study With MDV3100 and a Cocktail of Substrates
Conditions: Castration Resistant Prostate Cancer (CRPC);   Pharmacokinetics of MDV3100
Interventions: Drug: MDV3100;   Drug: Pioglitazone;   Drug: Warfarin;   Drug: Omeprazole;   Drug: Midazolam
36 Completed A Study to Compare Capsule and Tablet Forms of MDV3100 (Enzalutamide) After Administration of a Single Set Dose Under Fasted Conditions in Healthy Male Subjects
Conditions: Healthy Subjects;   Castration Resistant Prostate Cancer (CRPC);   Relative Bioavailability;   MDV3100
Intervention: Drug: MDV3100
37 Active, not recruiting A Study to Test if MDV3100 is Effective and Safe in Prostate Cancer Patients Who Have Never Had Hormone Therapy
Condition: Prostate Cancer
Intervention: Drug: MDV3100
38 Recruiting Enzalutamide + External Beam Rt For Prostate
Condition: Intermediate Risk Prostate Cancer
Interventions: Drug: Enzalutamide;   Radiation: External Beam Radiation
39 Terminated
Has Results
A Phase 3 Efficacy Study Of Dimebon In Patients With Moderate To Severe Alzheimer's Disease
Condition: Alzheimer Disease
Interventions: Drug: Dimebon 20 mg po TID;   Drug: Placebo po TID
40 Recruiting Enzalutamide, Radiation Therapy and Hormone Therapy in Treating Patients With Intermediate or High-Risk Prostate Cancer
Conditions: Adenocarcinoma of the Prostate;   Recurrent Prostate Cancer;   Stage IIB Prostate Cancer;   Stage III Prostate Cancer;   Stage IV Prostate Cancer
Interventions: Drug: Enzalutamide;   Drug: Goserelin acetate;   Drug: Leuprolide acetate;   Radiation: Radiation therapy

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Indicates status has not been verified in more than two years