65 studies found for:    Medivation
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Rank Status Study
21 Active, not recruiting
Has Results
Safety and Efficacy Study of MDV3100 in Patients With Castration-Resistant Prostate Cancer Who Have Been Previously Treated With Docetaxel-based Chemotherapy
Condition: Castration-Resistant Prostate Cancer
Interventions: Drug: Enzalutamide;   Drug: Placebo
22 Completed Safety Study of the Novel Drug Dimebon to Treat Patients With Huntington's Disease
Condition: Huntington's Disease
Intervention: Drug: Dimebon
23 Completed An Extension of the HORIZON Protocol Evaluating the Safety of Dimebon (Latrepirdine) in Subjects With Huntington Disease
Condition: Huntington Disease
Intervention: Drug: Dimebon (latrepirdine)
24 Not yet recruiting Randomized Salvage Radiation Therapy Plus Enzalutamide Post Prostatectomy
Condition: Adenocarcinoma of the Prostate
Interventions: Drug: Enzalutamide;   Radiation: SRT
25 Completed A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers
Conditions: Alzheimer's Disease;   Huntington's Disease
Interventions: Drug: Dimebon alone;   Drug: Dimebon + Ketoconazole;   Drug: Dimebon + Omeprazole
26 Completed A Phase 1, Randomized, Open-Label, Two-Way Crossover Study To Evaluate The Steady-State Effect Of Dimebon (PF 01913539) On The Single-Dose Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy Subjects
Conditions: Alzheimer's Disease;   Huntington's Disease
Interventions: Drug: Warfarin;   Drug: Dimebon
27 Completed A Phase 1 Trial To Assess The Safety And Pharmacokinetics Of Single, Ascending, Oral Doses Of Dimebon In Healthy Adults
Condition: Healthy Volunteers
Intervention: Drug: Dimebon
28 Recruiting A Study to Evaluate Enzalutamide After Abiraterone in Metastatic Castration-Resistant Prostate Cancer
Condition: Metastatic Castration-Resistant Prostate Cancer
Intervention: Drug: Enzalutamide
29 Approved for marketing Provide Expanded Access to MDV3100 and Monitor Its Safety in Patients With Progressive Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy
Condition: Metastatic Castration-Resistant Prostate Cancer
Intervention: Drug: MDV3100
30 Completed Drug-drug Interaction Study With MDV3100 and a Cocktail of Substrates
Conditions: Castration Resistant Prostate Cancer (CRPC);   Pharmacokinetics of MDV3100
Interventions: Drug: MDV3100;   Drug: Pioglitazone;   Drug: Warfarin;   Drug: Omeprazole;   Drug: Midazolam
31 Completed A Study to Evaluate How Daily Dosing With Enzalutamide Affects the Metabolism of Caffeine and Dextromethorphan in Men With Prostate Cancer
Conditions: Pharmacokinetics of Caffeine;   Pharmacokinetics of Dextromethorphan;   Prostate Cancer
Interventions: Drug: Caffeine;   Drug: Dextromethorphan;   Drug: Enzalutamide;   Drug: Enzalutamide Placebo to Match (PTM)
32 Completed A Phase 1 Study To Evaluate The Effect Of Dimebon On The Pharmacokinetics Of Dextromethorphan
Conditions: Huntington Disease;   Alzheimer Disease
Interventions: Drug: Dextromethorphan;   Drug: Dimebon + Dextromethorphan
33 Completed Drug-drug Interaction Study With MDV3100 (ASP9785) and Gemfibrozil and Itraconazole
Conditions: Healthy Subjects;   Pharmacokinetics;   Drug-Drug Interaction
Interventions: Drug: MDV3100;   Drug: Gemfibrozil;   Drug: Itraconazole
34 Completed A Study Evaluating The Absorption Of Dimebon Into The Body From A Dimebon Solution Applied To The Skin
Conditions: Alzheimer's Disease;   Huntington's Disease
Interventions: Drug: Dimebon IR;   Drug: Dimebon Transdermal
35 Completed Hepatic Impairment Study With MDV3100 in Subjects With Mild and Moderate Hepatic Impairment Compared to a Healthy Control Group
Conditions: Pharmacokinetics of MDV3100;   Healthy Subjects;   Kidney Diseases
Intervention: Drug: MDV3100
36 Completed Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [Pf-01913539] In Subjects With Hepatic Impairment And Normal Hepatic Function
Condition: Hepatic Failure
Intervention: Drug: Dimebon
37 Completed A Study to Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men
Conditions: Drug-Drug Interaction (DDI);   Healthy Subjects;   Pharmacokinetics of Enzalutamide
Interventions: Drug: enzalutamide;   Drug: rifampin
38 Recruiting Enzalutamide in Patients With Androgen Receptor Positive (AR+) Ovarian, Primary Peritoneal or Fallopian Tube Cancer and One, Two or Three Prior Therapies
Conditions: Advanced Epithelial Ovarian;   Recurrent Epithelial Ovarian;   Fallopian Tube;   Primary Peritoneal Carcinoma.
Intervention: Drug: Enzalutamide
39 Recruiting Abiraterone Acetate Plus LHRH Agonist and Abiraterone Acetate Plus LHRH Agonist and Enzalutamide
Condition: Prostate Cancer
Interventions: Drug: Abiraterone Acetate;   Drug: Prednisone;   Drug: Enzalutamide;   Drug: LHRHa
40 Completed A Phase 1 Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF-01913539] In Japanese And Western Healthy Subjects
Conditions: Alzheimer's Disease;   Huntington's Disease
Intervention: Drug: Dimebon

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Indicates status has not been verified in more than two years