66 studies found for:    Medivation
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Rank Status Study
21 Completed Determine the Effect of MDV3100 on the Androgen Signaling Pathway in Correlation With the Anti-tumor Effects of MDV3100 to Identify Potential Predictors of Response or Resistance to Therapy
Condition: Metastatic Progressive Castration-resistant Prostate Cancer
Intervention: Drug: MDV3100
22 Terminated A Safety and Efficacy Study Evaluating Dimebon (Latrepirdine) in Patients With Moderate to Severe Alzheimer's Disease
Condition: Moderate to Severe Alzheimer
Interventions: Drug: Dimebon (latrepirdine);   Drug: Placebo
23 Active, not recruiting
Has Results
Safety and Efficacy Study of MDV3100 in Patients With Castration-Resistant Prostate Cancer Who Have Been Previously Treated With Docetaxel-based Chemotherapy
Condition: Castration-Resistant Prostate Cancer
Interventions: Drug: Enzalutamide;   Drug: Placebo
24 Completed A Phase 1 Trial To Assess The Safety And Pharmacokinetics Of Single, Ascending, Oral Doses Of Dimebon In Healthy Adults
Condition: Healthy Volunteers
Intervention: Drug: Dimebon
25 Completed Hepatic Impairment Study With MDV3100 in Subjects With Mild and Moderate Hepatic Impairment Compared to a Healthy Control Group
Conditions: Pharmacokinetics of MDV3100;   Healthy Subjects;   Kidney Diseases
Intervention: Drug: MDV3100
26 Terminated
Has Results
An Extension To The B1451027 Protocol To Evaluate The Long Term Safety And Tolerability Of Dimebon In Patients With Alzheimer's Disease
Condition: Alzheimer's Disease
Intervention: Drug: Dimebon
27 Completed A Study to Compare Capsule and Tablet Forms of MDV3100 (Enzalutamide) After Administration of a Single Set Dose Under Fasted Conditions in Healthy Male Subjects
Conditions: Healthy Subjects;   Castration Resistant Prostate Cancer (CRPC);   Relative Bioavailability;   MDV3100
Intervention: Drug: MDV3100
28 Active, not recruiting A Study to Test if MDV3100 is Effective and Safe in Prostate Cancer Patients Who Have Never Had Hormone Therapy
Condition: Prostate Cancer
Intervention: Drug: MDV3100
29 Terminated
Has Results
An Extension To The B1451006 Protocol To Evaluate The Safety and Efficacy of Dimebon In Subjects With Moderate-to-Severe Alzheimer's Disease
Condition: Alzheimer's Disease
Intervention: Drug: Dimebon tablet for oral administration
30 Active, not recruiting A Study to Assess the Safety of Continued Administration of MDV3100 in Subjects With Prostate Cancer Who Showed Benefit From Prior Exposure to MDV3100
Condition: Castration-Resistant Prostate Cancer (CRPC)
Intervention: Drug: MDV3100
31 Completed A Phase 1, Randomized, Open-Label, Two-Way Crossover Study To Evaluate The Steady-State Effect Of Dimebon (PF 01913539) On The Single-Dose Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy Subjects
Conditions: Alzheimer's Disease;   Huntington's Disease
Interventions: Drug: Warfarin;   Drug: Dimebon
32 Recruiting Abiraterone Acetate Plus LHRH Agonist and Abiraterone Acetate Plus LHRH Agonist and Enzalutamide
Condition: Prostate Cancer
Interventions: Drug: Abiraterone Acetate;   Drug: Prednisone;   Drug: Enzalutamide;   Drug: LHRHa
33 Recruiting Enzalutamide in Patients With Androgen Receptor Positive (AR+) Ovarian, Primary Peritoneal or Fallopian Tube Cancer and One, Two or Three Prior Therapies
Conditions: Advanced Epithelial Ovarian;   Recurrent Epithelial Ovarian;   Fallopian Tube;   Primary Peritoneal Carcinoma.
Intervention: Drug: Enzalutamide
34 Completed A Study to Investigate the Effect of Severely Diminished Liver Function on the Metabolism, Safety, and Tolerability of a Single Oral Dose of Enzalutamide in Men
Conditions: Severe Hepatic Impairment;   Normal Hepatic Function
Intervention: Drug: enzalutamide
35 Not yet recruiting Randomized Salvage Radiation Therapy Plus Enzalutamide Post Prostatectomy
Condition: Adenocarcinoma of the Prostate
Interventions: Drug: Enzalutamide;   Radiation: SRT
36 Completed Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [Pf-01913539] In Subjects With Hepatic Impairment And Normal Hepatic Function
Condition: Hepatic Failure
Intervention: Drug: Dimebon
37 Completed A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)
Conditions: Alzheimer's Disease;   Huntington Disease
Interventions: Drug: Dimebon IR Tablet;   Drug: Dimebon MR1;   Drug: Dimebon MR2;   Drug: Dimebon MR3;   Drug: Dimebon MR4
38 Completed Drug-drug Interaction Study With MDV3100 and a Cocktail of Substrates
Conditions: Castration Resistant Prostate Cancer (CRPC);   Pharmacokinetics of MDV3100
Interventions: Drug: MDV3100;   Drug: Pioglitazone;   Drug: Warfarin;   Drug: Omeprazole;   Drug: Midazolam
39 Recruiting Phase II Trial of Enzalutamide for Castrate-resistant Prostate Cancer With Correlative Assessment of Androgen Receptor Signaling
Condition: Prostate Cancer
Intervention: Drug: Enzalutamide
40 Recruiting Enzalutamide With or Without Abiraterone Acetate and Prednisone in Treating Patients With Castration-Resistant Metastatic Prostate Cancer
Conditions: Adenocarcinoma of the Prostate;   Hormone-resistant Prostate Cancer;   Recurrent Prostate Cancer;   Stage IV Prostate Cancer
Interventions: Drug: enzalutamide;   Drug: abiraterone;   Drug: prednisone

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Indicates status has not been verified in more than two years