65 studies found for:    Medivation
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21 Terminated A Safety and Efficacy Study Evaluating Dimebon (Latrepirdine) in Patients With Moderate to Severe Alzheimer's Disease
Condition: Moderate to Severe Alzheimer
Interventions: Drug: Dimebon (latrepirdine);   Drug: Placebo
22 Active, not recruiting A Safety and Efficacy Study of Oral MDV3100 in Chemotherapy-Naive Patients With Progressive Metastatic Prostate Cancer
Condition: Prostate Cancer
Interventions: Drug: MDV3100;   Drug: Placebo
23 Completed Study of MDV3100 as a Neoadjuvant Therapy for Patients Undergoing Prostatectomy for Localized Prostate Cancer
Condition: Prostate Cancer
Interventions: Drug: MDV3100;   Drug: MDV3100 + Leuprolide + Dutasteride
24 Completed Dimebon (PF-01913539)-Digoxin Drug-Drug Interaction Study In Healthy Subjects
Conditions: Alzheimer Disease;   Huntington Disease
Interventions: Drug: digoxin;   Drug: dimebon
25 Completed
Has Results
A Phase 3 Study To Evaluate The Safety And Tolerability Of Dimebon Patients With Mild To Moderate Alzheimer's Disease
Condition: Alzheimer's Disease
Interventions: Drug: Dimebon;   Drug: Placebo
26 Active, not recruiting A Study of MDV3100 Versus Bicalutamide in Castrate Men With Metastatic Prostate Cancer
Condition: Prostatic Neoplasms
Interventions: Drug: MDV3100;   Drug: Bicalutamide
27 Completed A Study Evaluating The Absorption Of Dimebon Into The Body From A Dimebon Solution Applied To The Skin
Conditions: Alzheimer's Disease;   Huntington's Disease
Interventions: Drug: Dimebon IR;   Drug: Dimebon Transdermal
28 Withdrawn A Study to Evaluate the Safety and Efficacy of Enzalutamide in Chemotherapy-Naïve, Symptomatic Patients With Metastatic Castration-Resistant Prostate Cancer
Condition: Metastatic Castration-Resistant Prostate Cancer
Intervention: Drug: Enzalutamide
29 Completed A Study to Explore the Routes of Elimination of MDV3100
Conditions: Healthy Subjects;   Pharmacokinetics of MDV3100
Intervention: Drug: MDV3100
30 Completed A Phase 1 Trial To Assess The Safety And Pharmacokinetics Of Single, Ascending, Oral Doses Of Dimebon In Healthy Adults
Condition: Healthy Volunteers
Intervention: Drug: Dimebon
31 Completed A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)
Conditions: Alzheimer's Disease;   Huntington Disease
Interventions: Drug: Dimebon IR Tablet;   Drug: Dimebon MR1;   Drug: Dimebon MR2;   Drug: Dimebon MR3;   Drug: Dimebon MR4
32 Completed Drug-drug Interaction Study With MDV3100 and a Cocktail of Substrates
Conditions: Castration Resistant Prostate Cancer (CRPC);   Pharmacokinetics of MDV3100
Interventions: Drug: MDV3100;   Drug: Pioglitazone;   Drug: Warfarin;   Drug: Omeprazole;   Drug: Midazolam
33 Completed Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [Pf-01913539] In Subjects With Hepatic Impairment And Normal Hepatic Function
Condition: Hepatic Failure
Intervention: Drug: Dimebon
34 Completed Hepatic Impairment Study With MDV3100 in Subjects With Mild and Moderate Hepatic Impairment Compared to a Healthy Control Group
Conditions: Pharmacokinetics of MDV3100;   Healthy Subjects;   Kidney Diseases
Intervention: Drug: MDV3100
35 Completed A Phase 1, Randomized, Open-Label, Two-Way Crossover Study To Evaluate The Steady-State Effect Of Dimebon (PF 01913539) On The Single-Dose Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy Subjects
Conditions: Alzheimer's Disease;   Huntington's Disease
Interventions: Drug: Warfarin;   Drug: Dimebon
36 Recruiting Phase II Trial of Enzalutamide for Castrate-resistant Prostate Cancer With Correlative Assessment of Androgen Receptor Signaling
Condition: Prostate Cancer
Intervention: Drug: Enzalutamide
37 Recruiting Enzalutamide With or Without Abiraterone Acetate and Prednisone in Treating Patients With Castration-Resistant Metastatic Prostate Cancer
Conditions: Adenocarcinoma of the Prostate;   Hormone-resistant Prostate Cancer;   Recurrent Prostate Cancer;   Stage IV Prostate Cancer
Interventions: Drug: enzalutamide;   Drug: abiraterone;   Drug: prednisone
38 Recruiting Salvage Therapeutic Radiation With Enzalutamide and ADT in Men With Recurrent Prostate Cancer (STREAM)
Condition: Prostate Cancer
Interventions: Drug: enzalutamide;   Drug: Androgen Deprivation;   Radiation: Radiation Therapy
39 Active, not recruiting A Study to Test if MDV3100 is Effective and Safe in Prostate Cancer Patients Who Have Never Had Hormone Therapy
Condition: Prostate Cancer
Intervention: Drug: MDV3100
40 Completed A Study to Compare Capsule and Tablet Forms of MDV3100 (Enzalutamide) After Administration of a Single Set Dose Under Fasted Conditions in Healthy Male Subjects
Conditions: Healthy Subjects;   Castration Resistant Prostate Cancer (CRPC);   Relative Bioavailability;   MDV3100
Intervention: Drug: MDV3100

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Indicates status has not been verified in more than two years