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278 studies found for:    KRAS

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Rank Status Study
1 Unknown † KRAS Mutation and Incidence of the Colorectal Carcinoma in Martinique Between 2007 and 2009
Condition: Colorectal Carcinoma
Intervention:
2 Recruiting Randomized Phase II Study of AZD6244 (Mitogen-activated Protein Kinase Inhibitor) MEK-Inhibitor With Erlotinib in KRAS Wild Type Advanced Non-Small Cell Lung Cancer (NSCLC) and a Randomized Phase II Study of AZD6244 With Erlotinib in Mutant KRAS Adva...
Condition: Non Small Cell Lung Carcinoma
Interventions: Drug: AZD6244;   Drug: Erlotinib;   Drug: AZD6244 + Erlotinib
3 Completed MEK Inhibitor MSC1936369B Plus FOLFIRI in Second Line K-Ras Mutated Metastatic Colorectal Cancer (mCRC)
Condition: Metastatic Colorectal Cancer
Interventions: Drug: Mek Inhibitor MSC1936369B;   Drug: Placebo;   Drug: FOLFIRI
4 Enrolling by invitation Medical Records Review to Describe the Patterns of KRAS Testing and Vectibix Use in Europe
Condition: Metastatic Colorectal Cancer
Intervention: Other: Other
5 Recruiting Feasibility of the Research for Mutation of K-ras and EGFR in CTCs From Metastatic Non Small Cells Bronchial Carcinomas
Condition: Non-small Cell Lung Cancer Metastatic
Intervention: Biological: CTC
6 Active, not recruiting Ph2 Biomarker (Mechanism of K-ras Dependency) in Wt KRAS Metastatic Colorectal Cancer Patients
Condition: Metastatic Colorectal Cancer
Interventions: Drug: Panitumumab plus AMG 479;   Drug: Panitumumab plus Irinotecan
7 Recruiting Prevalence of the Mutational Status of V-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) in Metastatic Colorectal Cancer (mCRC) in Argentine Patients
Condition: Colorectal Neoplasms
Intervention:
8 Recruiting A Trial to Assess Sorafenib in Combination With Irinotecan in Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors
Condition: Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors
Interventions: Drug: Sorafenib and irinotecan combination;   Drug: Sorafenib monotherapy;   Drug: Irinotecan monotherapy
9 Completed Epidemiologic Study of KRAS Mutation in Brazilian Patients With Advanced or Metastatic Non Small Cell Lung Cancer
Condition: Non Small Cell Lung Cancer
Intervention:
10 Recruiting Bortezomib in KRAS-Mutant Non-Small Cell Lung Cancer in Never Smokers or Those With KRAS G12D
Condition: Non-Small Cell Lung Cancer
Interventions: Drug: Bortezomib;   Drug: Acyclovir
11 Not yet recruiting Efficacy of FOLFOX Versus FOLFOX Plus Aflibercept in K-ras Mutant Patients With Resectable Liver Metastases
Conditions: Colorectal Cancer Metastatic;   Liver Metastases;   KRAS Mutated Colorectal Cancer
Interventions: Drug: Modified FOLFOX6;   Biological: Aflibercept;   Procedure: Surgery
12 Active, not recruiting Avastin and Chemotherapy Followed by a KRAS Stratified Randomization to Maintenance Treatment for First Line Treatment of Metastatic Colorectal Cancer.
Condition: Colorectal Cancer
Interventions: Drug: bevacizumab, erlotinib;   Drug: bevacizumab;   Drug: low dose capecitabine
13 Recruiting ASPECCT: A Study of Panitumumab Efficacy and Safety Compared to Cetuximab in Subjects With KRAS Wild-Type Metastatic Colorectal Cancer
Condition: Metastatic Colorectal Cancer
Interventions: Drug: Cetuximab (Erbitux);   Drug: Panitumumab (Vectibix)
14 Withdrawn Study of Capecitabine and Cetuximab as First-Line Therapy in Patients With Metastatic Wild Type Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Colorectal Cancer
Condition: Metastatic Colorectal Cancer
Intervention: Drug: capecitabine and cetuximab
15 Completed KRAS Wild-type Metastatic Colorectal Cancer Trial
Condition: Colorectal Cancer
Interventions: Drug: Dacogen™ (decitabine);   Drug: Vectibix® (panitumumab)
16 Active, not recruiting A Trial to Compare Oxaliplatin, Folinic Acid (FA) and 5-Fluorouracil (5FU) Combination Chemotherapy (FOLFOX-4) With or Without Cetuximab in the 1st Line Treatment of Metastatic Colorectal Cancer (mCRC) in Chinese V-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Wild-type Patients
Condition: Metastatic Colorectal Cancer
Interventions: Drug: Cetuximab + Oxaliplatin + 5FU/FA;   Drug: Oxaliplatin + 5FU/FA
17 Completed K-RAS Oncogene Mutation in Patients With Advanced Non-Small Cell Lung Cancer Associated With Exposure to Wood Smoke and Tobacco Smoking: Therapeutic Implications
Condition: Non-Small Cell Lung Cancer
Intervention:
18 Active, not recruiting Comparison of AZD6244 in Combination With Docetaxel Versus Docetaxel Alone in KRAS Mutation Positive Non Small Cell Lung Cancer (NSCLC) Patients
Condition: Non Small Cell Lung Cancer
Interventions: Drug: AZD6244;   Drug: docetaxel;   Drug: Placebo
19 Completed Irinotecan, Cetuximab and Everolimus to Patients With Metastatic Colorectal Cancer
Condition: Metastatic Colorectal Cancer
Intervention: Drug: Everolimus
20 Recruiting Panitumumab After Resection of Liver Metastases From Colorectal Cancer in KRAS Wild-type Patients
Conditions: Colorectal Cancer;   KRAS Wildtype;   After Resection of Liver Metastases
Interventions: Drug: Folic Acid;   Drug: 5-FU;   Drug: Oxaliplatin;   Drug: Panitumumab
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† Indicates status has not been verified in more than two years