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79 studies found for:    Emphysema: Clinical Trials
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Rank Status Study
1 Active, not recruiting Clinical Trial to Evaluate the Safety and Effectiveness of the IBV® Valve System for the Treatment of Severe Emphysema
Conditions: Emphysema;   COPD
Intervention: Device: IBV®  Valve System
2 Unknown  EUROPT Clinical Trial to Study the Efficacy of One-Way Valve Implantation (New Treatment Algorithm) in Patients With Heterogeneous Emphysema
Conditions: Emphysema;   Chronic Obstructive Pulmonary Disease
Intervention: Procedure: Bronchoscopic Lung Volume Reduction (BLVR)
3 Recruiting Doxycycline for COPD in HIV-Infected Patients
Conditions: HIV;   Chronic Obstructive Pulmonary Disease (COPD);   Emphysema
Intervention: Drug: Doxycycline
4 Completed Endobronchial Valve for Emphysema Palliation Trial (VENT)
Conditions: Chronic Obstructive Pulmonary Disease;   Emphysema
Intervention: Procedure: Emphasys Endobronchial Valve and procedure
5 Completed
Has Results
Alpha-1-Antitrypsin (AAT) To Treat Emphysema In AAT-Deficient Patients (EXACTLE)
Condition: Alpha 1-Antitrypsin Deficiency
Interventions: Drug: Alpha1-Proteinase Inhibitor (Human);   Drug: Albumin (Human) 20%, United States Pharmacopeia (USP)
6 Terminated Endobronchial Valve for Emphysema PalliatioN Trial (VENT) Cost-effectiveness Sub-Study
Conditions: Emphysema;   Chronic Obstructive Pulmonary Disease
Intervention: Device: Emphasys Endobronchial Valve (EBV) Device and Procedure
7 Enrolling by invitation LVRC IDE Crossover Study (Crossover From IDE Trial CLN0009)
Condition: Emphysema
Intervention: Device: LVRC System
8 Unknown  The Value of Bronchoscopic Lung Volume Reduction by Endobronchial Valves in Patients With Single Lung Transplantation and Overinflation of the Native Lung
Condition: Native Lung Overinflation in Patients That Underwent Single Lung Transplantation Due to Emphysema
Intervention: Device: lung volume reduction using the Zephyr device
9 Completed National Emphysema Treatment Trial (NETT)
Conditions: Emphysema;   Lung Diseases;   Lung Diseases, Obstructive;   Chronic Obstructive Pulmonary Disease
Intervention: Procedure: Lung volume reduction surgery
10 Unknown  EASE Trial: Exhale Airway Stents for Emphysema
Condition: Emphysema
Interventions: Device: Exhale® Drug-Eluting Stent;   Device: Sham control
11 Recruiting To Improve Lung Function and Symptoms for Emphysema Patients Using Zephyr EBV
Conditions: COPD;   Heterogeneous Emphysema
Intervention: Device: ELVR (Endoscopic Lung Volume Reduction) with Zephyr valve
12 Recruiting Endoscopic Lung Volume Reduction After Catheter-based CV Measurement in Patients With Heterogeneous Emphysema and Complete Interlobar Fissures
Condition: Heterogeneous Emphysema
Intervention: Device: Implantation of valves (IBV)
13 Recruiting Clinical Study of the Efficacy and Safety of the Application of Allogeneic Mesenchymal (Stromal) Cells of Bone Marrow, Cultured Under the Hypoxia in the Treatment of Patients With Severe Pulmonary Emphysema
Condition: Pulmonary Emphysema
Interventions: Biological: Mesenchymal stem cells;   Other: Reference therapy: 400 mL of 0.9% NaCl solution
14 Completed
Has Results
Add-on Effects of Tiotropium Over Formoterol in Exercise Tolerance on Chronic Obstructive Pulmonary Disease Patients
Conditions: Pulmonary Disease, Chronic Obstructive;   Chronic Bronchitis;   Pulmonary Emphysema
Interventions: Drug: Formoterol plus Placebo (Tiotropium);   Drug: Formoterol plus Tiotropium
15 Completed Aclidinium/Formoterol Fixed Combination Dose Finding Study
Condition: Chronic Obstructive Pulmonary Disease
Interventions: Drug: Aclidinium bromide and formoterol;   Drug: Aclidinium bromide and formoterol placebo
16 Completed Feasibility of Retinoic Acid Treatment in Emphysema (FORTE)
Conditions: Emphysema;   Lung Diseases;   Lung Diseases, Obstructive;   Chronic Obstructive Pulmonary Disease
Interventions: Drug: all trans retinoic acid;   Drug: 13 cis retinoic acid;   Drug: placebo
17 Recruiting ART - Alveolar Recruitment for Acute Respiratory Distress Syndrome Trial
Condition: Respiratory Distress Syndrome, Adult
Interventions: Other: ART Strategy;   Other: ARDSNet Strategy
18 Recruiting Sustained Aeration of Infant Lungs Trial
Conditions: Preterm Birth;   Extreme Prematurity
Interventions: Procedure: Sustained Inflation;   Procedure: Standard of Care
19 Completed Very Early Surfactant and NCPAP for Premature Infants With RDS
Conditions: Respiratory Distress Syndrome;   Pneumothorax/Pulmonary Intersticial Emphysema;   Chronic Lung Disease
Interventions: Other: Very early surfactant and bubble NCPAP;   Other: bubble NCPAP
20 Unknown  AeriSeal System in Patients With Advanced Upper Lobe Predominant Emphysema and Collateral Ventilation
Conditions: Pulmonary Emphysema;   COPD;   Lung Diseases
Intervention: Device: AeriSeal System

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Indicates status has not been verified in more than two years