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811 studies found for:    ESR1

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Rank Status Study
1 Not yet recruiting Validation of [18F]FES for Imaging of Brain Estrogen Receptors
Conditions: Psychiatric/Mood Disorder / Patient;   Estrogen Receptor Levels;   Premenopausal;   Postmenopausal
Intervention: Procedure: FES-PET
2 Recruiting An Open Label Study of Postmenopausal Women With Oestrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Treated With Everolimus (RAD001) With Exemestane, With Exploratory Epigenetic Marker Analysis
Condition: Oestrogen Receptor Positive Advanced Breast Cancer
Interventions: Drug: RAD001;   Drug: Exemestane
3 Active, not recruiting Eribulin in Combination With Capecitabine for Adjuvant Treatment in Estrogen Receptor-Positive Early Stage Breast Cancer
Conditions: Estrogen Receptor Positive Tumor;   Breast Cancer
Intervention: Drug: E7389 (eribulin mesylate) and capecitabine
4 Recruiting BKM120 and Fulvestrant for Treating Postmenopausal Patients With Estrogen Receptor-Positive Stage IV Breast Cancer
Conditions: Estrogen Receptor-positive Breast Cancer;   Recurrent Breast Cancer;   Stage IV Breast Cancer
Interventions: Drug: PI3K inhibitor BKM120;   Drug: fulvestrant;   Procedure: biopsy
5 Completed
Has Results 		A Study of the Effect of Estrogen on Estrogen Receptor Biomarkers in Healthy Postmenopausal Women
Condition: Postmenopause
Interventions: Drug: Comparator: placebo;   Drug: Comparator: Estrace
6 Recruiting Broccoli Sprout Extract in Treating Patients With Estrogen Receptor-Positive Breast Cancer
Conditions: Estrogen Receptor-positive Breast Cancer;   Invasive Ductal Breast Carcinoma;   Invasive Lobular Breast Carcinoma;   Stage IA Breast Cancer;   Stage IB Breast Cancer;   Stage II Breast Cancer
Interventions: Drug: broccoli sprout extract;   Other: placebo;   Other: laboratory biomarker analysis
7 Recruiting Tamoxifen Citrate in Treating Premenopausal Women With Estrogen Receptor-Positive Breast Cancer
Conditions: Estrogen Receptor-positive Breast Cancer;   Stage I Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer;   Stage IV Breast Cancer
Interventions: Drug: tamoxifen citrate;   Genetic: polymerase chain reaction;   Other: pharmacological study;   Genetic: gene expression analysis;   Other: immunohistochemistry staining method;   Other: pharmacogenomic studies;   Other: matrix-assisted laser desorption/ionization time of flight mass spectrometry;   Genetic: polymorphism analysis;   Procedure: therapeutic conventional surgery;   Genetic: nucleic acid sequencing;   Genetic: protein analysis
8 Recruiting Ruxolitinib in Estrogen Receptor Positive Breast Cancer
Condition: Estrogen-receptor Positive Invasive Metastatic Breast Cancer
Intervention: Drug: Ruxolitinib
9 Suspended Goserelin and Letrozole or Anastrozole in Premenopausal Patients With Stage II-III Estrogen Receptor-Positive Breast Cancer
Conditions: Estrogen Receptor-positive Breast Cancer;   HER2-negative Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
Interventions: Drug: goserelin acetate;   Drug: letrozole;   Drug: anastrozole;   Drug: chemotherapy;   Procedure: Surgery
10 Completed Fulvestrant (FASLODEX™) as a Treatment in Postmenopausal Women With Estrogen Receptor Positive Breast Cancer
Condition: Breast Cancer
Intervention: Drug: Fulvestrant
11 Active, not recruiting Epidemiology Study in Postmenopausal Women With Estrogen Receptor Positive Breast Cancer
Condition: Hormon Receptor Positive Breast Cancer
Intervention:
12 Active, not recruiting
Has Results 		Everolimus in Combination With Exemestane in the Treatment of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Who Are Refractory to Letrozole or Anastrozole
Condition: Breast Cancer
Interventions: Drug: Everolimus;   Drug: Placebo;   Drug: Exemestane
13 Unknown † Selective Estrogen Receptor Modulators - A Potential Treatment for Psychotic Symptoms of Schizophrenia
Conditions: Schizophrenia;   Schizoaffective Disorder;   Schizophreniform Disorder
Interventions: Drug: Raloxifene hydrochloride;   Other: Lactose Capsules
14 Recruiting Selective Estrogen Receptor Modulators (SERMs) - A Potential Treatment for Psychotic Symptoms of Schizophrenia in Men?
Conditions: Schizophrenia;   Schizoaffective Disorder;   Schizophreniform Disorder
Interventions: Drug: Raloxifene Hydrochloride;   Drug: Placebo
15 Completed The Use of Selective Estrogen Receptor Modulators in the Treatment of Schizophrenia- a Pilot Study
Conditions: Schizophrenia;   Schizoaffective Disorder;   Schizophreniform Disorder
Interventions: Drug: Raloxifene;   Drug: Estradiol/dyhydroprogestrone
16 Recruiting Gene-polymorphisms Relating to Human Subfertility
Conditions: Estradiol Receptor Polymorphism;   Progesterone Receptor Polymorphism;   IVF;   Subfertility
Intervention:
17 Active, not recruiting
Has Results 		Comparison of Fulvestrant (FASLODEX™) 250 mg and 500 mg in Postmenopausal Women With Oestrogen Receptor Positive Advanced Breast Cancer Progressing or Relapsing After Previous Endocrine Therapy.
Condition: Breast Cancer
Intervention: Drug: Fulvestrant
18 Recruiting A Study of BYL719 in Adult Patients With Advanced Solid Malignancies, Whose Tumors Have an Alteration of the PIK3CA Gene
Conditions: Advanced Solid Tumors With an Alteration of the PIK3CA Gene;   Estrogen Receptor Positive Breast Cancer
Interventions: Drug: BYL719;   Drug: Fulvestrant
19 Completed Estrogen Receptor Gene Mutations
Conditions: Mutations;   Hormones
Intervention:
20 Recruiting Raloxifene and Rimostil for Perimenopause-Related Depression
Conditions: Perimenopausal Depression;   Depression
Interventions: Drug: Raloxefine (Evista);   Drug: Rimostil;   Drug: Evista, Rimostil, Alora
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† Indicates status has not been verified in more than two years