1198 studies found for:    ESR1
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Rank Status Study
1 Recruiting Validation of [18F]FES for Imaging of Brain Estrogen Receptors
Conditions: Psychiatric/Mood Disorder | Patient;   Estrogen Receptor Levels;   Premenopausal;   Postmenopausal
Intervention: Procedure: FES-PET
2 Completed
Has Results
A Study of the Effect of Estrogen on Estrogen Receptor Biomarkers in Healthy Postmenopausal Women (0000-094)(COMPLETED)
Condition: Postmenopause
Interventions: Drug: Comparator: placebo;   Drug: Comparator: Estrace
3 Active, not recruiting An Open Label Study of Postmenopausal Women With Oestrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Treated With Everolimus (RAD001) With Exemestane, With Exploratory Epigenetic Marker Analysis
Condition: Oestrogen Receptor Positive Advanced Breast Cancer
Interventions: Drug: RAD001;   Drug: Exemestane
4 Active, not recruiting Eribulin in Combination With Capecitabine for Adjuvant Treatment in Estrogen Receptor-Positive Early Stage Breast Cancer
Conditions: Estrogen Receptor Positive Tumor;   Breast Cancer
Intervention: Drug: E7389 (eribulin mesylate) and capecitabine
5 Active, not recruiting BKM120 and Fulvestrant for Treating Postmenopausal Patients With Estrogen Receptor-Positive Stage IV Breast Cancer
Conditions: Estrogen Receptor-positive Breast Cancer;   Recurrent Breast Cancer;   Stage IV Breast Cancer
Interventions: Drug: BKM120;   Drug: Fulvestrant;   Procedure: biopsy
6 Recruiting Tamoxifen Citrate in Treating Premenopausal Women With Estrogen Receptor-Positive Breast Cancer
Conditions: Estrogen Receptor-positive Breast Cancer;   Stage I Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer;   Stage IV Breast Cancer
Interventions: Drug: tamoxifen citrate;   Genetic: polymerase chain reaction;   Other: pharmacological study;   Genetic: gene expression analysis;   Other: immunohistochemistry staining method;   Other: pharmacogenomic studies;   Other: matrix-assisted laser desorption/ionization time of flight mass spectrometry;   Genetic: polymorphism analysis;   Procedure: therapeutic conventional surgery;   Genetic: nucleic acid sequencing;   Genetic: protein analysis
7 Active, not recruiting Ruxolitinib in Estrogen Receptor Positive Breast Cancer
Condition: Estrogen-receptor Positive Invasive Metastatic Breast Cancer
Intervention: Drug: Ruxolitinib
8 Recruiting Fluorestradiol (FES) PET/CT for Imaging Estrogen Receptor Status
Condition: Breast Cancer
Interventions: Drug: Fluorestradiol (FES);   Procedure: PET/CT Imaging
9 Not yet recruiting Adjuvant Endocrine Therapy for Estrogen Receptor-beta Positive Triple Negative Breast Cancer
Condition: Female Breast Cancer
Intervention: Drug: Toremifene; Anastrozole
10 Terminated Goserelin and Letrozole or Anastrozole in Premenopausal Patients With Stage II-III Estrogen Receptor-Positive Breast Cancer
Conditions: Estrogen Receptor-positive Breast Cancer;   HER2-negative Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
Interventions: Drug: goserelin acetate;   Drug: letrozole;   Drug: anastrozole;   Drug: chemotherapy;   Procedure: Surgery
11 Recruiting Broccoli Sprout Extract in Treating Patients With Estrogen Receptor-Positive Breast Cancer
Conditions: Estrogen Receptor-positive Breast Cancer;   Invasive Ductal Breast Carcinoma;   Invasive Lobular Breast Carcinoma;   Stage IA Breast Cancer;   Stage IB Breast Cancer;   Stage II Breast Cancer
Interventions: Drug: broccoli sprout extract;   Other: placebo;   Other: laboratory biomarker analysis
12 Completed Fulvestrant (FASLODEX™) as a Treatment in Postmenopausal Women With Estrogen Receptor Positive Breast Cancer
Condition: Breast Cancer
Intervention: Drug: Fulvestrant
13 Recruiting The Efficacy and Safety of a Selective Estrogen Receptor Beta Agonist (LY500307) for Negative Symptoms and Cognitive Impairment Associated With Schizophrenia
Condition: Schizophrenia
Interventions: Drug: LY500307 150mg;   Drug: LY500307 75mg;   Drug: Placebo
14 Completed Estrogen Receptor Beta Agonists (Eviendep) and Polyp Recurrence
Condition: Adenocarcinoma of Colon Recurrent
Interventions: Dietary Supplement: Eviendep (CM&D Pharma Limited, UK);   Dietary Supplement: Maltodextrins
15 Active, not recruiting
Has Results
Everolimus in Combination With Exemestane in the Treatment of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Who Are Refractory to Letrozole or Anastrozole
Condition: Breast Cancer
Interventions: Drug: Everolimus;   Drug: Placebo;   Drug: Exemestane
16 Recruiting Selective Estrogen Receptor Modulators - A Potential Treatment for Psychotic Symptoms of Schizophrenia
Conditions: Schizophrenia;   Schizoaffective Disorder;   Schizophreniform Disorder
Interventions: Drug: Raloxifene hydrochloride;   Other: Lactose Capsules
17 Completed Epidemiology Study in Postmenopausal Women With Estrogen Receptor Positive Breast Cancer
Condition: Hormon Receptor Positive Breast Cancer
Intervention:
18 Recruiting Selective Estrogen Receptor Modulators (SERMs) - A Potential Treatment for Psychotic Symptoms of Schizophrenia in Men?
Conditions: Schizophrenia;   Schizoaffective Disorder;   Schizophreniform Disorder
Interventions: Drug: Raloxifene Hydrochloride;   Drug: Placebo
19 Completed The Use of Selective Estrogen Receptor Modulators in the Treatment of Schizophrenia- a Pilot Study
Conditions: Schizophrenia;   Schizoaffective Disorder;   Schizophreniform Disorder
Interventions: Drug: Raloxifene;   Drug: Estradiol/dyhydroprogestrone
20 Not yet recruiting Estradiol-Receptor Blockade in Older Men and Women
Condition: Normal Healthy Volunteers
Interventions: Drug: Toremifene;   Drug: Placebo;   Drug: GHRH/Ghrelin combined Injection

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Indicates status has not been verified in more than two years