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21 studies found for:    Dimebon Alzheimer's

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1 Withdrawn A Study Of Oral PF-01913539 In Patients With Mild To Moderate Alzheimer's Disease
Conditions: Alzheimer's Disease;   Dementia;   Dimebon;   Investigational Drug
Interventions: Drug: PF-01913539 5 mg;   Drug: Placebo
2 Completed A Safety and Efficacy Study of Oral Dimebon in Patients With Mild-To-Moderate Alzheimer's Disease
Condition: Alzheimer's Disease
Interventions: Drug: Dimebon;   Drug: Placebo
3 Completed
Has Results 		A Phase 3 Study To Evaluate The Safety And Tolerability Of Dimebon Patients With Mild To Moderate Alzheimer's Disease
Condition: Alzheimer's Disease
Interventions: Drug: Dimebon;   Drug: Placebo
4 Completed Safety and Efficacy Study Evaluating Dimebon in Patients With Mild to Moderate Alzheimer's Disease on Donepezil
Condition: Alzheimer's Disease
Interventions: Drug: Dimebon;   Drug: Placebo comparator
5 Unknown † Double-Blind, Placebo-Controlled Study of Oral Dimebon in Subjects With Mild to Moderate Alzheimer's Disease
Condition: Alzheimer's Disease
Intervention: Drug: Dimebon
6 Terminated
Has Results 		A Phase 3 Efficacy Study Of Dimebon In Patients With Moderate To Severe Alzheimer's Disease
Condition: Alzheimer Disease
Interventions: Drug: Dimebon 20 mg po TID;   Drug: Placebo po TID
7 Unknown † Safety and Tolerability of Dimebon in Patients on Memantine, and Memantine Plus Donepezil
Condition: Alzheimer's Disease
Interventions: Drug: Dimebon;   Drug: Placebo
8 Terminated
Has Results 		An Extension To The B1451006 Protocol To Evaluate The Safety and Efficacy of Dimebon In Subjects With Moderate-to-Severe Alzheimer's Disease
Condition: Alzheimer's Disease
Intervention: Drug: Dimebon tablet for oral administration
9 Unknown † Study of Combination Therapy With Dimebon and Donepezil (Aricept) in Patients With Alzheimer's Disease
Condition: Alzheimer's Disease
Intervention: Drug: dimebon
10 Terminated
Has Results 		An Extension To The B1451027 Protocol To Evaluate The Long Term Safety And Tolerability Of Dimebon In Patients With Alzheimer's Disease
Condition: Alzheimer's Disease
Intervention: Drug: Dimebon
11 Terminated A Safety and Efficacy Study Evaluating Dimebon (Latrepirdine) in Patients With Moderate to Severe Alzheimer's Disease
Condition: Moderate to Severe Alzheimer
Interventions: Drug: Dimebon (latrepirdine);   Drug: Placebo
12 Terminated An Extension of the CONCERT Protocol (DIM18)
Condition: Alzheimer's Disease
Intervention: Drug: Dimebon
13 Completed A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)
Conditions: Alzheimer's Disease;   Huntington Disease
Interventions: Drug: Dimebon IR Tablet;   Drug: Dimebon MR1;   Drug: Dimebon MR2;   Drug: Dimebon MR3;   Drug: Dimebon MR4
14 Completed A Study Evaluating The Absorption Of Dimebon Into The Body From A Dimebon Solution Applied To The Skin
Conditions: Alzheimer's Disease;   Huntington's Disease
Interventions: Drug: Dimebon IR;   Drug: Dimebon Transdermal
15 Completed A Phase 1, Randomized, Open-Label, Two-Way Crossover Study To Evaluate The Steady-State Effect Of Dimebon (PF 01913539) On The Single-Dose Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy Subjects
Conditions: Alzheimer's Disease;   Huntington's Disease
Interventions: Drug: Warfarin;   Drug: Dimebon
16 Completed A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers
Conditions: Alzheimer's Disease;   Huntington's Disease
Interventions: Drug: Dimebon alone;   Drug: Dimebon + Ketoconazole;   Drug: Dimebon + Omeprazole
17 Completed A Phase 1 Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF-01913539] In Japanese And Western Healthy Subjects
Conditions: Alzheimer's Disease;   Huntington's Disease
Intervention: Drug: Dimebon
18 Completed A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal Function
Conditions: Alzheimer's Disease;   Huntington's Disease
Intervention: Drug: Dimebon
19 Completed
Has Results 		A Study To Evaluate The Abuse Potential Of Single Oral Doses Of Dimebon (Latrepirdine) In Healthy Recreational Polydrug Users
Conditions: Alzheimer's Disease;   Huntington's Disease
Interventions: Drug: dimebon;   Drug: placebo;   Drug: alprazolam
20 Completed Dimebon (PF-01913539)-Digoxin Drug-Drug Interaction Study In Healthy Subjects
Conditions: Alzheimer Disease;   Huntington Disease
Interventions: Drug: digoxin;   Drug: dimebon
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† Indicates status has not been verified in more than two years