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27 studies found for:    5-HT1A

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Rank Status Study
1 Recruiting Evaluation of [18F]MPPF as a Brain Tracer of Serotonin Receptor 5HT1a
Condition: Parkinson Disease
Intervention: Drug: [18F]MPPF
2 Withdrawn Imaging Serotonin 5HT1A Receptors in Patients With Major Depressive Disorder
Conditions: Major Depression;   Unipolar Depression;   Depression;   Anxiety Disorder
Intervention: Other: Antidepressant (SSRI)
3 Completed Brain Chemical Receptor Effects in Patients With Panic Disorder and Post-Traumatic Stress Disorder
Conditions: Panic Disorder;   Posttraumatic Stress Disorder;   Major Depressive Disorder
Intervention:
4 Completed Study Evaluating Safety, Tolerability, Pharmacokinetics and 5 HT1A Receptor Occupancy
Condition: Alzheimer's Disease
Intervention: Drug: SRA-444
5 Recruiting Investigation of the Serotoninergic System in Multiple System Atrophy: a Positron Emission Tomography (PET) Study
Condition: Multiple System Atrophy
Interventions: Radiation: PET (Positron Emission Tomography) Study;   Other: Brain MRI (magnetic resonance imaging);   Drug: Fluoxétine / Placebo
6 Completed Effects of Electroconvulsive Therapy (ECT) on Serotonin-1A Receptor Binding
Condition: Unipolar Depression
Intervention: Procedure: ECT
7 Completed PET Whole Body Distribution Studies Using [11C]CUMI
Conditions: Depression;   Major Depression;   Unipolar Depression;   Anxiety Disorder;   Anxiety Disorders
Intervention:
8 Completed PET Imaging of Brain 5-HT(1A) Receptors Using [(11)C](-)-RWAY
Condition: Healthy Volunteers
Intervention: Drug: [11C] (-)-RWAY
9 Completed Study Of Safety, Blood Levels, And Brain Receptor Occupancy Of GSK163090 Using PET Imaging In Healthy Males
Conditions: Healthy Subjects;   Depressive Disorder and Anxiety Disorders
Intervention: Drug: GSK163090
10 Enrolling by invitation The Effect of Neu-P11 on Symptoms in Patients With D-IBS
Condition: Diarrhea- Irritable Bowel Syndrome
Interventions: Drug: Neu-P11;   Drug: Placebo
11 Completed Examination of Brain Serotonin Receptors in Patients With Mood Disorders
Conditions: Mood Disorder;   Bipolar Disorder;   Depression
Intervention:
12 Recruiting Hormonal Causes of Menstrual-Related Mood Disorders
Conditions: Mood Disorders;   Premenstrual Syndrome;   PMS;   PMDD;   Depression;   Healthy
Intervention:
13 Completed Serotonin Receptors in Seizure Disorders
Condition: Partial Epilepsy
Intervention:
14 Not yet recruiting PET Trial to Assess the Receptor Occupancy of Brexpiprazole in Adult Subjects With Schizophrenia
Condition: Schizophrenia
Intervention: Drug: Brexpiprazole 1mg to 4mg
15 Recruiting (18F)FCWAY and the Blood-Brain Barrier
Condition: Drug Resistance
Intervention:
16 Terminated Fluoxetine Versus Fluoxetine Plus DU125530 in Major Depressive Disorder
Condition: Major Depression
Interventions: Drug: DU125530;   Drug: Placebo
17 Completed Citalopram Versus Citalopram Plus Pindolol in Major Depressive Disorder
Conditions: Major Depressive Disorder;   Antidepressant Treatment Response
Intervention: Drug: Pindolol
18 Completed Treatment-Resistant Depression, Hippocampus Atrophy and Serotonin Genetic Polymorphism
Condition: Major Depression
Intervention: Other: Open label pharmacotherapy
19 Completed Study Evaluating the Safety of Lecozotan SR in Healthy Young and Elderly Subjects
Condition: Alzheimer Disease
Intervention: Drug: Lecozotan SR
20 Completed FTIH Study With GSK958108
Condition: Premature Ejaculation
Intervention: Drug: GSK958108
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† Indicates status has not been verified in more than two years