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United States, Texas | United States, Texas | cook children's (267 records)
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Rank Status Study
1 Recruiting National Marrow Donor Program Long-Term Donor Follow-Up
Condition: Hematologic Neoplasms
Intervention:
2 Recruiting A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)
Conditions: Hematological Malignancies;   Certain Lysosomal Storage and Peroxisomal Enzyme Deficiency Disorders;   Hurler Syndrome (MPS I);   Krabbe Disease (Globoid Leukodystrophy);   X-linked Adrenoleukodystrophy;   Primary Immunodeficiency Diseases;   Bone Marrow Failure;   Beta-thalassemia
Intervention: Drug: A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs)
3 Unknown † Study of Weekly ALTU-238 Compared With Daily Nutropin AQ in Prepubertal Children With Growth Hormone Deficiency
Condition: Growth Hormone Deficiency
Intervention: Drug: Somatropin
4 Unknown † Patient Plasma Response and Outcome in Septic Shock With Thrombocytopenia Associated Multiple Organ Failure in Children
Conditions: Septic Shock;   Thrombocytopenia;   Multiple Organ Failure
Intervention:
5 Recruiting Evaluation of the Duration of Therapy for Thrombosis in Children
Condition: Venous Thrombosis
Interventions: Other: Shortened duration (6 weeks) of anticoagulant therapy;   Other: Conventional duration (3 months) of anticoagulant therapy;   Other: No Intervention;   Drug: Dalteparin
6 Completed Study of Bendamustine Hydrochloride for the Treatment of Pediatric Patients With Relapsed or Refractory Acute Leukemia
Condition: Leukemia
Intervention: Drug: Bendamustine
7 Recruiting Defibrotide for Patients With Hepatic Veno-occlusive Disease: A Treatment IND Study
Condition: Hepatic Veno-Occlusive Disease
Intervention: Drug: Defibrotide
8 Completed Chart Review of Antivirals for Influenza in Infants
Condition: Influenza
Intervention:
9 Recruiting Safety and Efficacy Study of Daptomycin in Pediatric Subjects (2-17 Years)With Skin and Skin Structure Infections
Condition: Skin Diseases, Infectious
Interventions: Drug: Daptomycin;   Drug: Vancomycin, Clindamycin or semi-synthetic Penicillins
10 Recruiting Protocol for Collecting, Banking and Distributing Human Tissue Samples: St. Jude Children's Research Hospital Tissue Resources Core Facility
Condition: Normal and Diseased Tissue and Body Fluids Samples
Intervention:
11 Recruiting Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma
Conditions: Contiguous Stage II Adult Lymphoblastic Lymphoma;   Noncontiguous Stage II Adult Lymphoblastic Lymphoma;   Stage II Adult T-cell Leukemia/Lymphoma;   Stage II Childhood Lymphoblastic Lymphoma;   Stage III Adult Lymphoblastic Lymphoma;   Stage III Adult T-cell Leukemia/Lymphoma;   Stage III Childhood Lymphoblastic Lymphoma;   Stage IV Adult Lymphoblastic Lymphoma;   Stage IV Adult T-cell Leukemia/Lymphoma;   Stage IV Childhood Lymphoblastic Lymphoma;   T-cell Adult Acute Lymphoblastic Leukemia;   T-cell Childhood Acute Lymphoblastic Leukemia;   Untreated Adult Acute Lymphoblastic Leukemia;   Untreated Childhood Acute Lymphoblastic Leukemia
Interventions: Drug: doxorubicin hydrochloride;   Drug: cytarabine;   Drug: daunorubicin hydrochloride;   Drug: prednisone;   Drug: pegaspargase;   Drug: methotrexate;   Drug: leucovorin calcium;   Drug: cyclophosphamide;   Drug: mercaptopurine;   Drug: nelarabine;   Drug: asparaginase;   Drug: dexamethasone;   Drug: thioguanine;   Drug: vincristine sulfate;   Radiation: radiation therapy;   Other: laboratory biomarker analysis
12 Unknown † Rituximab to Treat Severe Hemophilia A
Condition: Hemophilia A
Intervention: Drug: Rituximab
13 Active, not recruiting
Has Results 		Study of Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Homozygous for the F508del-CFTR Mutation
Condition: Cystic Fibrosis
Interventions: Drug: Ivacaftor;   Drug: Placebo
14 Enrolling by invitation Littlears Auditory Questionnaire: Validation Study in CI Children
Condition: Hearing Loss
Intervention:
15 Active, not recruiting Phase I Study of GNKG168 in Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia
Conditions: Relapsed Acute Lymphoblastic Leukemia;   Relapsed Acute Myelogenous Leukemia
Intervention: Drug: GNKG168
16 Active, not recruiting Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Conditions: Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia;   Philadelphia Chromosome Positive Childhood Precursor Acute Lymphoblastic Leukemia;   Untreated Adult Acute Lymphoblastic Leukemia;   Untreated Childhood Acute Lymphoblastic Leukemia
Interventions: Drug: asparaginase;   Drug: dasatinib;   Drug: daunorubicin hydrochloride;   Drug: prednisone;   Drug: methylprednisolone;   Drug: methotrexate;   Drug: cytarabine;   Drug: etoposide;   Drug: ifosfamide;   Biological: filgrastim;   Drug: leucovorin calcium;   Drug: cyclophosphamide;   Drug: pegaspargase;   Drug: dexamethasone;   Drug: mercaptopurine;   Radiation: radiation therapy;   Drug: hydrocortisone sodium succinate;   Drug: vincristine sulfate;   Other: laboratory biomarker analysis
17 Recruiting Sorafenib Tosylate in Treating Younger Patients With Relapsed or Refractory Rhabdomyosarcoma, Wilms Tumor, Liver Cancer, or Thyroid Cancer
Conditions: Childhood Hepatocellular Carcinoma;   Papillary Thyroid Cancer;   Previously Treated Childhood Rhabdomyosarcoma;   Recurrent Childhood Liver Cancer;   Recurrent Childhood Rhabdomyosarcoma;   Recurrent Thyroid Cancer;   Recurrent Wilms Tumor and Other Childhood Kidney Tumors
Interventions: Drug: sorafenib tosylate;   Other: pharmacological study;   Other: laboratory biomarker analysis
18 Active, not recruiting
Has Results 		Therapy for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia
Condition: Lymphoblastic Leukemia, Acute
Interventions: Drug: Prednisone, Dexamethasone, Vincristine, Daunorubicin;   Drug: Doxorubicin, L-asparaginase, PEG-L-asparaginase, Erwinia asparaginase;   Drug: Methotrexate, Cyclophosphamide, Cytarabine, Etoposide;   Drug: Mercaptopurine, Imatinib;   Procedure: chemotherapy, intrathecal chemotherapy;   Procedure: steroid therapy, hematopoietic stem cell transplantation
19 Recruiting Isotretinoin With or Without Monoclonal Antibody, Interleukin-2, and Sargramostim Following Stem Cell Transplantation in Treating Patients With Neuroblastoma
Conditions: Disseminated Neuroblastoma;   Localized Resectable Neuroblastoma;   Localized Unresectable Neuroblastoma;   Regional Neuroblastoma;   Stage 4S Neuroblastoma
Interventions: Drug: isotretinoin;   Biological: sargramostim;   Biological: monoclonal antibody Ch14.18;   Biological: aldesleukin;   Other: laboratory biomarker analysis;   Procedure: quality-of-life assessment;   Other: pharmacological study
20 Recruiting International Pediatric Adrenocortical Tumor Registry
Condition: Adrenocortical Tumor
Intervention:
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† Indicates status has not been verified in more than two years