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275 studies found for:    United States, Texas | United States, Texas | cook children's
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Rank Status Study
21 Recruiting Childhood Cancer Survivor Study
Condition: Cancer
Intervention:
22 Active, not recruiting Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma
Conditions: Disseminated Neuroblastoma;   Localized Resectable Neuroblastoma;   Localized Unresectable Neuroblastoma;   Regional Neuroblastoma;   Stage 4S Neuroblastoma
Interventions: Drug: cyclophosphamide;   Drug: topotecan hydrochloride;   Drug: cisplatin;   Drug: etoposide;   Drug: vincristine sulfate;   Drug: doxorubicin hydrochloride;   Radiation: external beam radiation therapy;   Drug: busulfan;   Drug: melphalan;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: peripheral blood stem cell transplantation;   Other: pharmacological study;   Other: laboratory biomarker analysis;   Biological: filgrastim;   Drug: mesna
23 Recruiting Fluorodopa F 18 in Congenital Hyperinsulinism
Condition: Congenital Hyperinsulinism
Intervention: Drug: Fluorodopa F 18
24 Recruiting Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Conditions: Adult Acute Megakaryoblastic Leukemia;   Adult Acute Monoblastic Leukemia;   Adult Acute Monocytic Leukemia;   Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11;   Adult Acute Myeloid Leukemia With Maturation;   Adult Acute Myeloid Leukemia With Minimal Differentiation;   Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11;   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1;   Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL;   Adult Acute Myeloid Leukemia Without Maturation;   Adult Acute Myelomonocytic Leukemia;   Adult Erythroleukemia;   Adult Pure Erythroid Leukemia;   Childhood Acute Erythroid Leukemia;   Childhood Acute Megakaryoblastic Leukemia;   Childhood Acute Monoblastic Leukemia;   Childhood Acute Monocytic Leukemia;   Childhood Acute Myeloid Leukemia With Maturation;   Childhood Acute Myeloid Leukemia Without Maturation;   Childhood Acute Myelomonocytic Leukemia;   Untreated Adult Acute Myeloid Leukemia;   Untreated Childhood Myeloid Neoplasm
Interventions: Drug: Asparaginase;   Drug: Daunorubicin Hydrochloride;   Drug: Mitoxantrone Hydrochloride;   Drug: Sorafenib Tosylate;   Drug: Cytarabine;   Drug: Etoposide;   Drug: Bortezomib;   Other: Pharmacological Study;   Other: Laboratory Biomarker Analysis;   Other: Questionnaire Administration;   Other: Quality-of-Life Assessment
25 Completed A Multicenter, Open-label Study of CMX001 Treatment of Serious Diseases or Conditions Caused by dsDNA Viruses
Conditions: Male or Female Patients With a Serious or Immediately Life-threatening;   Disease or Condition Caused by CMV, ADV, HSV, VAVC, VARV or;   Monkeypox Viruses(s) Who Have a Life Expectancy of ≥ 2 Weeks and for;   Whom no Comparable or Satisfactory Alternative Therapy is Available
Intervention: Drug: CMX001
26 Suspended A Trial of Temsirolimus With Etoposide and Cyclophosphamide in Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins Lymphoma
Conditions: Lymphoblastic Leukemia, Acute, Childhood;   Lymphoblastic Lymphoma;   Peripheral T-cell Lymphoma
Interventions: Drug: Temsirolimus;   Drug: Dexamethasone;   Drug: Etoposide;   Drug: Etoposide phosphate;   Drug: Cyclophosphamide;   Drug: Methotrexate;   Drug: Hydrocortisone;   Drug: Cytarabine
27 Active, not recruiting Natural History Study of Infants With Adrenal Masses Found on Prenatal and/or Neonatal Imaging
Conditions: Adrenocortical Carcinoma;   Localized Resectable Neuroblastoma;   Precancerous Condition
Interventions: Procedure: computed tomography;   Procedure: 3-Tesla magnetic resonance imaging;   Procedure: Abdominal Sonogram
28 Active, not recruiting Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Promyelocytic Leukemia
Conditions: Childhood Acute Promyelocytic Leukemia (M3);   Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies
Interventions: Drug: arsenic trioxide;   Drug: mitoxantrone hydrochloride;   Other: diagnostic laboratory biomarker analysis;   Drug: idarubicin;   Drug: tretinoin;   Drug: cytarabine;   Drug: mercaptopurine tablet;   Drug: methotrexate
29 Completed Evaluation of a Video Game for Adolescents and Young Adults With Cancer
Condition: Neoplasms
Intervention: Behavioral: Re-Mission
30 Completed Pentostatin for High Risk and Refractory Chronic Graft Versus Host Disease in Children
Condition: Graft vs Host Disease
Intervention: Drug: Pentostatin
31 Active, not recruiting Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma
Conditions: Localized Osteosarcoma;   Metastatic Osteosarcoma
Interventions: Drug: doxorubicin hydrochloride;   Drug: cisplatin;   Drug: methotrexate;   Procedure: therapeutic conventional surgery;   Biological: peginterferon alfa-2b;   Drug: ifosfamide;   Drug: etoposide;   Procedure: quality-of-life assessment;   Other: questionnaire administration
32 Recruiting Risk-Adapted Chemotherapy in Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia
Conditions: B-cell Childhood Acute Lymphoblastic Leukemia;   Philadelphia Chromosome Positive Childhood Precursor Acute Lymphoblastic Leukemia;   Untreated Adult Acute Lymphoblastic Leukemia;   Untreated Childhood Acute Lymphoblastic Leukemia
Interventions: Drug: doxorubicin hydrochloride;   Drug: cytarabine;   Drug: vincristine sulfate;   Drug: dexamethasone;   Drug: pegaspargase;   Drug: methotrexate;   Drug: mercaptopurine tablet;   Drug: leucovorin calcium;   Drug: cyclophosphamide;   Drug: thioguanine;   Procedure: quality-of-life assessment;   Other: questionnaire administration;   Other: laboratory biomarker analysis
33 Active, not recruiting
Has Results
Erwinia Asparaginase After Allergy to PEG-Asparaginase in Treating Young Patients With Acute Lymphoblastic Leukemia
Conditions: Adult Acute Lymphoblastic Leukemia;   Childhood Acute Lymphoblastic Leukemia
Interventions: Other: laboratory biomarker analysis;   Other: pharmacological study;   Drug: asparaginase
34 Active, not recruiting Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Conditions: Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34;q11.2); BCR-ABL1;   Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34;q11.2); BCR-ABL1;   Untreated Adult Acute Lymphoblastic Leukemia;   Untreated Childhood Acute Lymphoblastic Leukemia
Interventions: Drug: Asparaginase;   Drug: Dasatinib;   Drug: Daunorubicin Hydrochloride;   Drug: Prednisone;   Drug: Methylprednisolone;   Drug: Methotrexate;   Drug: Cytarabine;   Drug: Etoposide;   Drug: Ifosfamide;   Biological: Filgrastim;   Drug: Leucovorin Calcium;   Drug: Cyclophosphamide;   Drug: Pegaspargase;   Drug: Dexamethasone;   Drug: Mercaptopurine;   Radiation: Radiation Therapy;   Drug: Hydrocortisone Sodium Succinate;   Drug: Vincristine Sulfate;   Other: Laboratory Biomarker Analysis
35 Active, not recruiting Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete Remission
Conditions: B-cell Childhood Acute Lymphoblastic Leukemia;   Childhood Acute Lymphoblastic Leukemia in Remission;   Graft Versus Host Disease;   L1 Childhood Acute Lymphoblastic Leukemia;   L2 Childhood Acute Lymphoblastic Leukemia;   T-cell Childhood Acute Lymphoblastic Leukemia
Interventions: Drug: thiotepa;   Drug: cyclophosphamide;   Drug: tacrolimus;   Drug: methotrexate;   Drug: sirolimus;   Radiation: total body irradiation
36 Recruiting Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor
Conditions: Diffuse Hyperplastic Perilobar Nephroblastomatosis;   Stage I Wilms Tumor;   Stage II Wilms Tumor;   Stage III Wilms Tumor;   Stage IV Wilms Tumor;   Stage V Wilms Tumor
Interventions: Drug: doxorubicin hydrochloride;   Procedure: therapeutic conventional surgery;   Biological: dactinomycin;   Drug: cyclophosphamide;   Drug: carboplatin;   Drug: etoposide phosphate;   Drug: vincristine sulfate;   Procedure: adjuvant therapy;   Procedure: neoadjuvant therapy
37 Completed Pharmacokinetics (PK) and Safety Evaluation of Daptomycin in Children Ages 3-24 Months With Proven or Suspected Gram-positive Infections or Peri-Operative Subjects Receiving Prophylactic Antibiotics
Condition: Gram Positive Bacterial Infection
Intervention: Drug: Daptomycin
38 Active, not recruiting Sunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or Ependymoma
Conditions: Childhood Cerebral Astrocytoma/Malignant Glioma;   Childhood High-grade Cerebellar Astrocytoma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Infratentorial Ependymoma;   Childhood Mixed Glioma;   Childhood Oligodendroglioma;   Childhood Supratentorial Ependymoma;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Subependymal Giant Cell Astrocytoma
Interventions: Drug: sunitinib malate;   Other: diagnostic laboratory biomarker analysis;   Other: pharmacological study
39 Active, not recruiting Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma
Conditions: Childhood Alveolar Soft-part Sarcoma;   Childhood Angiosarcoma;   Childhood Epithelioid Sarcoma;   Childhood Fibrosarcoma;   Childhood Gliosarcoma;   Childhood Leiomyosarcoma;   Childhood Liposarcoma;   Childhood Neurofibrosarcoma;   Childhood Synovial Sarcoma;   Previously Treated Childhood Rhabdomyosarcoma;   Recurrent Childhood Rhabdomyosarcoma;   Recurrent Childhood Soft Tissue Sarcoma;   Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Recurrent Osteosarcoma
Interventions: Biological: cixutumumab;   Drug: temsirolimus;   Other: laboratory biomarker analysis
40 Completed
Has Results
Efficacy and Safety of Palonosetron Intravenous in Prevention of Chemotherapy Induced Nausea and Vomiting in Pediatric Patients
Condition: Chemotherapy-Induced Nausea and Vomiting
Interventions: Drug: Palonosetron;   Drug: Ondansetron;   Drug: Placebo to Ondansetron;   Drug: Placebo to Palonosetron

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