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276 studies found for:    United States, Texas | United States, Texas | cook children's
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Rank Status Study
21 Active, not recruiting Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors
Conditions: Childhood Embryonal Tumor;   Childhood Extracranial Germ Cell Tumor;   Childhood Extragonadal Germ Cell Tumor;   Childhood Malignant Ovarian Germ Cell Tumor;   Childhood Malignant Testicular Germ Cell Tumor;   Childhood Teratoma;   Ovarian Embryonal Carcinoma;   Ovarian Yolk Sac Tumor;   Stage II Malignant Testicular Germ Cell Tumor;   Stage IIA Ovarian Germ Cell Tumor;   Stage IIB Ovarian Germ Cell Tumor;   Stage IIC Ovarian Germ Cell Tumor;   Stage III Malignant Testicular Germ Cell Tumor;   Stage IIIA Ovarian Germ Cell Tumor;   Stage IIIB Ovarian Germ Cell Tumor;   Stage IIIC Ovarian Germ Cell Tumor;   Testicular Choriocarcinoma and Yolk Sac Tumor;   Testicular Embryonal Carcinoma
Interventions: Procedure: conventional surgery;   Drug: cisplatin;   Drug: etoposide;   Biological: bleomycin sulfate;   Other: laboratory biomarker analysis
22 Active, not recruiting Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN #0601) (The SCURT Study)
Condition: Sickle Cell Disease
Intervention: Biological: Hematopoietic Stem Cell Transplantation
23 Active, not recruiting Combination Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin Lymphoma
Conditions: Childhood Nodular Lymphocyte Predominant Hodgkin Lymphoma;   Stage III Childhood Hodgkin Lymphoma;   Stage IV Childhood Hodgkin Lymphoma
Interventions: Biological: bleomycin sulfate;   Drug: doxorubicin hydrochloride;   Drug: liposomal vincristine sulfate;   Drug: vinorelbine tartrate;   Drug: cyclophosphamide;   Drug: etoposide phosphate;   Drug: prednisone;   Biological: filgrastim;   Drug: ifosfamide
24 Recruiting Pediatric Obesity Weight Evaluation Registry (POWER) Study
Conditions: Overweight;   Obesity
Intervention:
25 Active, not recruiting Inhaled Nitric Oxide (INO) for the Prevention of Bronchopulmonary Dysplasia (BPD) in Preterm Infants
Condition: Bronchopulmonary Dysplasia
Interventions: Drug: Inhaled Nitric Oxide;   Drug: Placebo
26 Recruiting Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma
Conditions: Recurrent Childhood Acute B-lymphoblastic Leukemia;   Recurrent Childhood B-lymphoblastic Lymphoma
Interventions: Drug: dexamethasone;   Drug: vincristine sulfate;   Biological: rituximab;   Drug: clofarabine;   Drug: cyclophosphamide;   Drug: etoposide;   Biological: aldesleukin;   Drug: pegaspargase;   Drug: methotrexate;   Drug: mercaptopurine;   Drug: cytarabine;   Drug: mitoxantrone;   Drug: teniposide;   Drug: vinblastine;   Biological: natural killer cell infusion;   Other: laboratory biomarker analysis;   Drug: therapeutic hydrocortisone;   Procedure: allogeneic hematopoietic stem cell transplantation
27 Recruiting Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Conditions: B-cell Adult Acute Lymphoblastic Leukemia;   B-cell Childhood Acute Lymphoblastic Leukemia;   T-cell Adult Acute Lymphoblastic Leukemia;   T-cell Childhood Acute Lymphoblastic Leukemia;   Untreated Adult Acute Lymphoblastic Leukemia;   Untreated Childhood Acute Lymphoblastic Leukemia
Interventions: Other: laboratory biomarker analysis;   Other: cytology specimen collection procedure
28 Recruiting Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma
Conditions: Untreated Childhood Medulloblastoma;   Untreated Childhood Pineoblastoma;   Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor
Interventions: Radiation: radiation therapy;   Drug: vincristine sulfate;   Drug: carboplatin;   Drug: cisplatin;   Drug: cyclophosphamide;   Biological: filgrastim;   Drug: isotretinoin;   Other: laboratory biomarker analysis;   Other: quality-of-life assessment
29 Active, not recruiting Cisplatin-Based Chemotherapy and/or Surgery in Treating Young Patients With Adrenocortical Tumor
Conditions: Stage I Adrenocortical Carcinoma;   Stage II Adrenocortical Carcinoma;   Stage III Adrenocortical Carcinoma;   Stage IV Adrenocortical Carcinoma
Interventions: Drug: doxorubicin hydrochloride;   Procedure: conventional surgery;   Drug: cisplatin;   Drug: mitotane;   Drug: etoposide;   Biological: filgrastim
30 Recruiting Childhood Cancer Survivor Study
Condition: Cancer
Intervention:
31 Recruiting Study of Kidney Tumors in Young Patients
Conditions: Clear Cell Sarcoma of the Kidney;   Congenital Mesoblastic Nephroma;   Diffuse Hyperplastic Perilobar Nephroblastomatosis;   Rhabdoid Tumor of the Kidney;   Stage I Renal Cell Cancer;   Stage I Wilms Tumor;   Stage II Renal Cell Cancer;   Stage II Wilms Tumor;   Stage III Renal Cell Cancer;   Stage III Wilms Tumor;   Stage IV Renal Cell Cancer;   Stage IV Wilms Tumor;   Stage V Wilms Tumor
Interventions: Other: laboratory biomarker analysis;   Other: cytology specimen collection procedure
32 Active, not recruiting Fludarabine-based Conditioning for Severe Aplastic Anemia
Condition: Anemia, Aplastic
Intervention: Drug: Cyclophosphamide
33 Active, not recruiting Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes
Conditions: Childhood Acute Basophilic Leukemia;   Childhood Acute Eosinophilic Leukemia;   Childhood Acute Erythroleukemia (M6);   Childhood Acute Megakaryocytic Leukemia (M7);   Childhood Acute Minimally Differentiated Myeloid Leukemia (M0);   Childhood Acute Monoblastic Leukemia (M5a);   Childhood Acute Monocytic Leukemia (M5b);   Childhood Acute Myeloblastic Leukemia With Maturation (M2);   Childhood Acute Myeloblastic Leukemia Without Maturation (M1);   Childhood Acute Myelomonocytic Leukemia (M4);   Childhood Myelodysplastic Syndromes;   de Novo Myelodysplastic Syndromes;   Secondary Acute Myeloid Leukemia;   Secondary Myelodysplastic Syndromes;   Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies
Interventions: Drug: asparaginase;   Drug: daunorubicin hydrochloride;   Drug: cytarabine;   Drug: thioguanine;   Drug: etoposide;   Other: laboratory biomarker analysis
34 Recruiting A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma
Condition: Medulloblastoma
Interventions: Radiation: Craniospinal Irradiation with boost to the primary tumor site;   Drug: Cyclophosphamide;   Drug: Cisplatin;   Drug: Vincristine;   Drug: Vismodegib;   Drug: Pemetrexed;   Drug: Gemcitabine;   Other: Aerobic Training;   Other: Neurocognitive Remediation
35 Completed Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia
Conditions: Childhood Hepatoblastoma;   Previously Treated Childhood Rhabdomyosarcoma;   Recurrent Childhood Acute Lymphoblastic Leukemia;   Recurrent Childhood Acute Myeloid Leukemia;   Recurrent Childhood Malignant Germ Cell Tumor;   Recurrent Childhood Rhabdomyosarcoma;   Recurrent Childhood Soft Tissue Sarcoma;   Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Recurrent Neuroblastoma;   Recurrent Osteosarcoma;   Recurrent Wilms Tumor and Other Childhood Kidney Tumors
Interventions: Drug: alisertib;   Other: pharmacological study;   Other: laboratory biomarker analysis
36 Completed
Has Results
RI-001 in Immunosuppressed Respiratory Syncytial Virus (RSV) Infected Patients at Risk of Lower Tract RSV Illness
Conditions: Upper Respiratory Tract Infection;   Lower Respiratory Tract Infection
Intervention: Biological: RI-001
37 Active, not recruiting Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma
Conditions: Adult Rhabdomyosarcoma;   Alveolar Childhood Rhabdomyosarcoma;   Embryonal Childhood Rhabdomyosarcoma;   Metastatic Childhood Soft Tissue Sarcoma;   Previously Untreated Childhood Rhabdomyosarcoma;   Stage IV Adult Soft Tissue Sarcoma
Interventions: Biological: cixutumumab;   Drug: doxorubicin hydrochloride;   Drug: irinotecan hydrochloride;   Drug: liposomal vincristine sulfate;   Drug: ifosfamide;   Drug: etoposide;   Drug: cyclophosphamide;   Biological: dactinomycin;   Drug: temozolomide;   Other: laboratory biomarker analysis
38 Recruiting International Pediatric Adrenocortical Tumor Registry
Condition: Adrenocortical Tumor
Intervention:
39 Recruiting Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma
Conditions: Adult Rhabdomyosarcoma;   Childhood Desmoplastic Small Round Cell Tumor;   Chordoma;   Desmoid Tumor;   Metastatic Childhood Soft Tissue Sarcoma;   Nonmetastatic Childhood Soft Tissue Sarcoma;   Previously Treated Childhood Rhabdomyosarcoma;   Previously Untreated Childhood Rhabdomyosarcoma;   Recurrent Adult Soft Tissue Sarcoma;   Recurrent Childhood Rhabdomyosarcoma;   Recurrent Childhood Soft Tissue Sarcoma;   Stage I Adult Soft Tissue Sarcoma;   Stage II Adult Soft Tissue Sarcoma;   Stage III Adult Soft Tissue Sarcoma;   Stage IV Adult Soft Tissue Sarcoma
Interventions: Other: biologic sample preservation procedure;   Other: laboratory biomarker analysis
40 Active, not recruiting The EPIC Observational Study
Condition: Cystic Fibrosis
Intervention:

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