395 studies found for:    Open Studies | Exclude Unknown | "neurological disorders"OR"brain tumors"OR"attention-deficit/hyperactivity disorder"OR"epilepsy"OR"chronic pain"OR"spincal cord injury"OR"stroke" | United States | Phase 1, 2, 3, 0 | Industry
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Rank Status Study
21 Recruiting GORE® HELEX® Septal Occluder / GORE® Septal Occluder for Patent Foramen Ovale (PFO) Closure in Stroke Patients - The Gore REDUCE Clinical Study
Conditions: Stroke;   Transient Ischemic Attack
Intervention: Device: GORE® HELEX® Septal Occluder / GORE® Septal Occluder
22 Recruiting Evaluating Long Term Safety of Lacosamide (LCM) to Carbamazepine Controlled-release (CBZ-CR); Initial Monotherapy in Epilepsy Subjects 16 Years and Older
Conditions: Epilepsy;   Monotherapy
Interventions: Drug: Lacosamide;   Drug: Carbamazepine-Controlled Release (CBZ-CR)
23 Recruiting Phase 3, Randomized, Placebo-Controlled, Double-Blinded Trial of the Combined Lysis of Thrombus With Ultrasound and Systemic Tissue Plasminogen Activator (tPA) for Emergent Revascularization in Acute Ischemic Stroke
Condition: Acute Ischemic Stroke
Interventions: Device: Transcranial ultrasound as an adjunctive therapy to tPA;   Drug: Standard of care tPA therapy for acute ischemic stroke
24 Recruiting Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma or Progressive Secondary Brain Tumor
Conditions: Glioma;   Glioblastoma;   Glioblastoma Multiforme;   GBM;   Brain Cancer
Intervention: Drug: VAL-083
25 Recruiting Study to Evaluate the Safety and Efficacy of USL261 in Patients With Increased Bouts of Seizure Activity in the EMU
Condition: Epilepsy
Interventions: Drug: USL261;   Drug: Placebo
26 Recruiting A Multicenter, Open-Label Study To Investigate The Safety And Pharmacokinetics Of Lacosamide In Children With Partial Seizures
Condition: Epilepsy
Intervention: Drug: Lacosamide
27 Recruiting Study to Evaluate the Long-term Safety and Tolerability of USL261 in Patients With Seizure Clusters
Condition: Epilepsy
Intervention: Drug: USL261
28 Recruiting Stroke Feasibility Study
Conditions: Atrial Fibrillation;   AFib
Intervention: Device: AtriClip LAA Exclusion Device
29 Recruiting A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Trial of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures
Condition: Partial Epilepsy
Interventions: Drug: YKP3089;   Drug: Placebo
30 Recruiting A 12-Month Study To Evaluate The Safety And Tolerability Of Pregabalin As Add-On Therapy In Pediatric Subjects 1 Month To 16 Years Of Age With Partial Onset Seizures And Pediatric And Adult Subjects 5 To 65 Years Of Age With Primary Generalized Tonic-Clonic Seizures
Condition: Epilepsy, Partial Seizures
Intervention: Drug: Pregabalin
31 Recruiting A Study of the Efficacy and Safety of Pregabalin as Add-On Therapy for Partial Onset Seizures in Children Ages 4-16 Years
Condition: Epilepsy, Partial Seizures
Intervention: Drug: Pregabalin add-on therapy
32 Recruiting Modified Atkins Diet Plus KetoCal for Adult Epilepsy
Conditions: Epilepsy;   Seizure;   Medically Resistant Epilepsy;   Medically Resistant Seizures
Interventions: Dietary Supplement: Modified Atkins diet;   Dietary Supplement: KetoCal
33 Recruiting NT0102 in the Treatment of Children With Attention Deficit Hyperactivity Disorder (ADHD)
Condition: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: Drug: NT0102;   Drug: Placebo
34 Recruiting A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following Hospitalization for Heart Failure
Conditions: Heart Failure;   Coronary Artery Disease
Interventions: Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
35 Recruiting Safety of Intravenous Thrombolysis for Wake-up Stroke
Condition: Ischemic Stroke
Intervention: Drug: Alteplase (iv t-PA)
36 Recruiting Insulin Resistance Intervention After Stroke Trial
Conditions: Stroke;   Myocardial Infarction;   Diabetes
Interventions: Drug: pioglitazone;   Drug: placebo
37 Recruiting Safety of Intravenous Thrombolytics in Stroke on Awakening
Condition: Stroke
Intervention: Drug: rt-PA
38 Recruiting Cardiac Rhythm Abnormalities in Patients With Refractory Epilepsy at High Risk for Sudden Death
Conditions: Refractory Epilepsy;   Arrhythmia;   Sudden Death
Intervention: Device: Medtronic REVEAL
39 Not yet recruiting ASIS for Botox in Upper Limb Spasticity
Conditions: Upper Limb Spasticity Unilaterally in Adults With History of Stroke;   Increased Muscle Tone in Elbow, Wrist, Finger, and Thumb Flexors.
Interventions: Drug: Gadolinium;   Drug: Efficacy of Botox intramuscularly at Week 6;   Drug: Efficacy of Botox intramuscularly at Week 12,;   Drug: Efficacy of Botox intramuscularly at Week 18;   Drug: Efficacy of Botox intramuscularly at Week 24;   Drug: Efficacy of Botox intramuscularly at Week 30;   Drug: Efficacy of Botox subdermally at Week 6;   Drug: Efficacy of Botox subdermally at Week 12;   Drug: Efficacy of Botox subdermally at Week 18;   Drug: Efficacy of Botox subdermally at Week 24;   Drug: Efficacy of Botox subdermally at Week 30;   Drug: Adverse Reactions of Botox intramuscularly;   Drug: Adverse Reactions of Botox subdermally
40 Recruiting ANG1005 in Patients With Recurrent High-Grade Glioma
Conditions: Glioma;   Glioblastoma;   Brain Tumor, Recurrent
Interventions: Drug: ANG1005;   Drug: Bevacizumab

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Indicates status has not been verified in more than two years