421 studies found for:    Open Studies | Exclude Unknown | "heart disease"OR"stroke"OR"cardiovascular disease" | United States | Phase 1, 2, 3, 0 | Industry
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Open Studies | Exclude Unknown | "heart disease"OR"stroke"OR"cardiovascular disease" | United States | Phase 1, 2, 3, 0 | Industry
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Rank Status Study
1 Recruiting AMES Treatment of the Impaired Leg in Chronic Stroke Patients
Conditions: Stroke;   Cerebrovascular Accident;   Hemiparesis
Intervention: Device: AMES- Leg therapy
2 Recruiting A Study of Allogeneic Mesenchymal Bone Marrow Cells in Subjects With Ischemic Stroke
Condition: Ischemic Stroke
Intervention: Biological: Allogeneic adult mesenchymal bone marrow stem cells
3 Recruiting Study to Examine the Effects of MultiStem in Ischemic Stroke
Condition: Ischemic Stroke
Interventions: Biological: MultiStem;   Biological: Placebo
4 Recruiting A Randomized, Concurrent Controlled Trial to Assess the Safety and Effectiveness of the Separator 3D as a Component of the Penumbra System in the Revascularization of Large Vessel Occlusion in Acute Ischemic Stroke
Condition: Acute Ischemic Stroke From Large Vessel Occlusion
Interventions: Device: Penumbra System with Separator 3D;   Device: Penumbra System alone
5 Recruiting Efficacy and Safety Study of Desmoteplase to Treat Acute Ischemic Stroke (DIAS-4)
Condition: Stroke
Interventions: Drug: Desmoteplase;   Drug: Placebo
6 Recruiting Efficacy and Safety Study of GM602 in Patients With Acute Middle Cerebral Artery Ischemic Stroke Within 18 Hours
Condition: Stroke
Interventions: Drug: GM602;   Drug: Matching Placebo (Bacteriostatic Saline) for GM602
7 Recruiting [SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES]
Conditions: Acute Ischaemic Stroke;   Transient Ischaemic Attack.
Interventions: Drug: ticagrelor;   Drug: Acetylsalicylic acid (ASA)
8 Recruiting GORE® HELEX® Septal Occluder / GORE® Septal Occluder for Patent Foramen Ovale (PFO) Closure in Stroke Patients - The Gore REDUCE Clinical Study
Conditions: Stroke;   Transient Ischemic Attack
Intervention: Device: GORE® HELEX® Septal Occluder / GORE® Septal Occluder
9 Recruiting Effect of Natalizumab on Infarct Volume in Acute Ischemic Stroke
Condition: Acute Ischemic Stroke
Interventions: Biological: BG00002 (Natalizumab);   Drug: Placebo
10 Recruiting Glyburide Advantage in Malignant Edema and Stroke - Remedy Pharmaceuticals
Conditions: Ischemic Stroke;   Malignant Edema
Intervention: Drug: RP-1127 (Glyburide for Injection)
11 Recruiting POC in Patients With Ischaemic Stroke
Condition: Cerebrovascular Accident
Interventions: Drug: GSK249320 100/mg;   Drug: Placebo
12 Recruiting Implant for Augmentation of Cerebral Blood Flow Trial, Effectiveness and Safety in a 24 Hour Window
Condition: Ischemic Stroke
Interventions: Device: The Ischemic Stroke System;   Device: Sham control
13 Recruiting Stroke Feasibility Study
Conditions: Atrial Fibrillation;   AFib
Intervention: Device: AtriClip LAA Exclusion Device
14 Recruiting Phase 3, Randomized, Placebo-Controlled, Double-Blinded Trial of the Combined Lysis of Thrombus With Ultrasound and Systemic Tissue Plasminogen Activator (tPA) for Emergent Revascularization in Acute Ischemic Stroke
Condition: Acute Ischemic Stroke
Interventions: Device: Transcranial ultrasound as an adjunctive therapy to tPA;   Drug: Standard of care tPA therapy for acute ischemic stroke
15 Recruiting A Study of Rivaroxaban (JNJ-39039039) on the Venous Thromboembolic Risk in Post-Hospital Discharge Patients
Conditions: Heart Failure;   Respiratory Insufficiency;   Stroke Acute;   Infectious Diseases;   Rheumatic Diseases
Interventions: Drug: Rivaroxaban, 10 mg;   Drug: Rivaroxaban, 7.5 mg;   Drug: Placebo
16 Recruiting A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following Hospitalization for Heart Failure
Conditions: Heart Failure;   Coronary Artery Disease
Interventions: Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
17 Recruiting Intracardiac CrYoablation for AtrioVentricular Nodal Reentrant Tachycardia
Conditions: AtrioVentricular Nodal Reentrant Tachycardia;   Supraventricular Tachycardia;   Heart Disease
Intervention: Device: Freezor Xtra Cryoablation Catheter
18 Recruiting Safety of Intravenous Thrombolysis for Wake-up Stroke
Condition: Ischemic Stroke
Intervention: Drug: Alteplase (iv t-PA)
19 Recruiting Safety of Intravenous Thrombolytics in Stroke on Awakening
Condition: Stroke
Intervention: Drug: rt-PA
20 Not yet recruiting ASIS for Botox in Upper Limb Spasticity
Conditions: Upper Limb Spasticity Unilaterally in Adults With History of Stroke;   Increased Muscle Tone in Elbow, Wrist, Finger, and Thumb Flexors.
Interventions: Drug: Gadolinium;   Drug: Efficacy of Botox intramuscularly at Week 6;   Drug: Efficacy of Botox intramuscularly at Week 12,;   Drug: Efficacy of Botox intramuscularly at Week 18;   Drug: Efficacy of Botox intramuscularly at Week 24;   Drug: Efficacy of Botox intramuscularly at Week 30;   Drug: Efficacy of Botox subdermally at Week 6;   Drug: Efficacy of Botox subdermally at Week 12;   Drug: Efficacy of Botox subdermally at Week 18;   Drug: Efficacy of Botox subdermally at Week 24;   Drug: Efficacy of Botox subdermally at Week 30;   Drug: Adverse Reactions of Botox intramuscularly;   Drug: Adverse Reactions of Botox subdermally

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Indicates status has not been verified in more than two years