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402 studies found for:    Open Studies | Exclude Unknown | "heart disease"OR"stroke"OR"cardiovascular disease" | United States | Phase 1, 2, 3, 0 | Industry
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Rank Status Study
21 Recruiting A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following Hospitalization for Heart Failure
Conditions: Heart Failure;   Coronary Artery Disease
Interventions: Drug: Rivaroxaban;   Drug: Placebo;   Other: Standard of care for heart failure and coronary artery disease
22 Recruiting Pharmacokinetic/Pharmacodynamic Study of Udenafil in Adolescents
Condition: Single Ventricle Heart Disease After Fontan Surgery
Intervention: Drug: Udenafil
23 Recruiting Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia
Condition: Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)
Interventions: Drug: Epanova® (omega-3 carboxylic acids);   Drug: corn oil control
24 Recruiting A Study of the Efficacy and Safety of Activase (Alteplase) in Patients With Mild Stroke (PRISMS)
Condition: Brain Ischemia
Interventions: Drug: alteplase [Activase];   Drug: alteplase placebo;   Drug: aspirin;   Drug: aspirin placebo
25 Recruiting Clinical Evaluation of the Blazer Open-Irrigated Ablation Catheter for the Treatment of Paroxysmal Atrial Fibrillation
Condition: Paroxysmal Atrial Fibrillation (PAF)
Interventions: Device: Blazer Open-Irrigated Ablation Catheter (Boston Scientific);   Device: FDA Approved Open-Irrigated Ablation Catheter
26 Recruiting MR WITNESS: A Study of Intravenous Thrombolysis With Alteplase in MRI-Selected Patients
Condition: Acute Stroke
Intervention: Drug: IV rt-PA
27 Recruiting A Pivotal Trial to Establish the Efficacy and Long-term Safety of the Parachute Implant System
Conditions: Congestive Heart Failure;   Left Ventricular (LV) Systolic Dysfunction
Intervention: Device: CardioKinetix Parachute Implant and All Appropriate Medical Therapy (AAMT)
28 Recruiting The Randomized Evaluation of VAD InterVEntion Before Inotropic Therapy
Condition: Congestive Heart Failure
Interventions: Device: HM II® (HeartMate II® LVAD);   Other: OMM (Optimal Medical Management)
29 Recruiting GORE® HELEX® Septal Occluder / GORE® Septal Occluder for Patent Foramen Ovale (PFO) Closure in Stroke Patients - The Gore REDUCE Clinical Study
Conditions: Stroke;   Transient Ischemic Attack
Intervention: Device: GORE® HELEX® Septal Occluder / GORE® Septal Occluder
30 Recruiting Phase 3, Randomized, Placebo-Controlled, Double-Blinded Trial of the Combined Lysis of Thrombus With Ultrasound and Systemic Tissue Plasminogen Activator (tPA) for Emergent Revascularization in Acute Ischemic Stroke
Condition: Acute Ischemic Stroke
Interventions: Device: Transcranial ultrasound as an adjunctive therapy to tPA;   Drug: Standard of care tPA therapy for acute ischemic stroke
31 Recruiting A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60)
Condition: Acute Coronary Syndrome
Interventions: Drug: Losmapimod 7.5 mg twice daily;   Drug: Placebo twice daily
32 Recruiting Cardiovascular Risk Reduction Study (Reduction in Recurrent Major CV Disease Events)
Condition: Atherosclerosis
Interventions: Drug: Canakinumab;   Drug: Placebo
33 Recruiting Right to Left Cardiac Shunt Detection
Conditions: Right to Left Shunt;   Patent Foramen Ovale;   Atrial Septal Defect
Intervention: Device: Flow Detection System
34 Recruiting Walking Effect of Long Term Ticagrelor in Subjects With PAD Who Have Undergone EVR
Condition: Peripheral Artery Disease (PAD)
Interventions: Drug: Ticagrelor;   Drug: Comparator
35 Recruiting Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease
Condition: Prevention & Control
Interventions: Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
36 Recruiting Use of Dexmedetomidine in Acute Stroke and Cerebral Vasospasm Interventions
Conditions: Stroke;   Brain Ischemia;   Vasospasm, Intracranial;   Hemorrhage, Intracranial
Interventions: Drug: Dexmedetomidine;   Drug: Fentanyl;   Drug: Midazolam
37 Recruiting Study of Botulinum Toxin and Recovery of Hand Function After Stroke
Condition: Stroke With Hemiparesis
Intervention: Drug: Botulinum Toxin commonly known as BOTOX®
38 Recruiting Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure
Conditions: Atrial Fibrillation;   Atrial Flutter
Interventions: Drug: bucindolol hydrochloride;   Drug: metoprolol succinate
39 Recruiting Effects of Resveratrol Supplements on Vascular Health in Postmenopausal Women
Condition: Cardiovascular Disease
Interventions: Dietary Supplement: ResA;   Dietary Supplement: Resveratrol;   Dietary Supplement: Placebo
40 Recruiting BIOHELIX-I Bare Metal Stent Study
Condition: Coronary Arteries Disease
Intervention: Device: PRO-Kinetic Energy Stent

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