34 studies found for:    FAMILIAL ADENOMATOUS POLYPOSIS 1
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Rank Status Study
1 Completed
Has Results
Chemoprevention Trial in Familial Adenomatous Polyposis (FAP) Coli Using EPA
Conditions: Familial Adenomatous Polyposis Coli;   FAP
Interventions: Drug: Eicosapentanoic Acid (EPA);   Procedure: Endoscopy;   Procedure: Biopsies taken;   Drug: Placebo
2 Terminated Trial In Pediatric Patients With Familial Adenomatous Polyposis (FAP)
Condition: Adenomatous Polyposis Coli
Interventions: Drug: Celecoxib;   Drug: Placebo
3 Terminated A Study of Rofecoxib in Familial Adenomatous Polyposis (FAP)
Condition: Adenomatous Polyposis Coli
Interventions: Drug: MK0966; rofecoxib / Duration of Treatment: 24 weeks;   Drug: Comparator: placebo / Duration of Treatment: 24 weeks
4 Recruiting Registry With Information About Colitis Ulcerosa and Familial Adenomatous Polyposis Patients
Conditions: Colitis,Ulcerative;   Adenomatous Polyposis Coli;   Reservoir, Ileoanal
Intervention:
5 Unknown  Influence of Sulindac and Probiotics on the Development of Pouch Adenomas in Patients With Familial Adenomatous Polyposis
Condition: Adenomatous Polyposis Coli
Interventions: Drug: Sulindac (drug);   Drug: VSL#3 (probiotic);   Drug: Inulin (probiotic)
6 Recruiting Molecular Fluorescence Endoscopy in Patients With Familial Adenomatous Polyposis, Using Bevacizumab-IRDye800CW
Condition: Adenomatous Polyposis Coli
Interventions: Drug: Bevacizumab-IRDye800CW;   Device: Near infrared fluorescence endoscopy platform
7 Active, not recruiting A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients
Condition: Adenomatous Polyposis Coli
Interventions: Drug: Erlotinib;   Drug: Sulindac;   Drug: Placebo A;   Drug: Placebo B
8 Unknown  Ursodeoxycholic Acid in the Treatment of Duodenal Adenomas in Familial Adenomatous Polyposis (FAP) Patients
Condition: Adenomatous Polyposis Coli, Familial
Interventions: Drug: Ursodeoxycholic acid;   Drug: Placebo
9 Recruiting Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutations in Familial Adenomatous Polyposis
Condition: FAP-Familial Adenomatous Polyposis
Intervention: Drug: Erythromycin
10 Completed Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis
Conditions: Colorectal Cancer;   Familial Adenomatous Polyposis
Interventions: Drug: celecoxib;   Other: placebo;   Drug: eflornithine;   Other: laboratory biomarker analysis;   Other: questionnaire administration
11 Completed A Cohort Study of Patients Treated With Brachytherapy for Selected Desmoid Patients in Gardner Syndrome
Conditions: Gardner Syndrome;   Colorectal Carcinoma;   Desmoid Tumor
Intervention:
12 Completed Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis
Conditions: Familial Adenomatous Polyposis;   Duodenal Neoplasms;   Duodenal Polyps
Interventions: Drug: Celecoxib;   Drug: Ursodeoxycholic acid;   Drug: Placebo
13 Active, not recruiting Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers
Condition: Familial Adenomatous Polyposis
Interventions: Drug: Celecoxib;   Procedure: Colonoscopy Biopsy
14 Withdrawn Use of Curcumin in the Lower Gastrointestinal Tract in Familial Adenomatous Polyposis Patients
Condition: Familial Adenomatous Polyposis
Intervention: Drug: curcumin
15 Recruiting Preliminary Evaluation of Septin9 in Patients With Hereditary Colon Cancer Syndromes
Conditions: Familial Adenomatous Polyposis;   Map Syndrome;   Lynch Syndrome;   Hnpcc;   Colorectal Cancer
Intervention: Other: Epi proColon Testing
16 Unknown  Adenoma Detection Rate:NBI, AFI, Chromoscopic or Standard Endoscopy
Condition: Familial Adenomatous Polyposis
Intervention: Procedure: flexible sigmoidoscopy
17 Terminated
Has Results
Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal Anastomoses
Conditions: Rectal Cancer;   Ulcerative Colitis;   Familial Adenomatous Polyposis;   Diverticulitis
Interventions: Device: GORE SEAMGUARD® Bioabsorbable Staple Line Reinforcement;   Procedure: Staple line without reinforcement
18 Withdrawn Exisulind in Preventing Polyps in Patients With Familial Adenomatous Polyposis
Conditions: Colorectal Cancer;   Small Intestine Cancer
Intervention: Drug: exisulind
19 Completed Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis
Conditions: Colorectal Cancer;   Precancerous Condition
Interventions: Drug: celecoxib;   Other: placebo
20 Recruiting The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study
Condition: Familial Adenomatous Polyposis
Intervention: Drug: metformin

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Indicates status has not been verified in more than two years