1806 studies found for:    "Sphingolipidosis"
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Rank Status Study
1 Unknown  Genetic Origin of Lipid Disorders
Condition: Lipid Disorder
Intervention:
2 Recruiting Natural History Study of Children With Metachromatic Leukodystrophy
Conditions: Leukodystrophy, Metachromatic;   Hereditary Central Nervous System Demyelinating Diseases;   Brain Diseases, Metabolic, Inborn;   Brain Diseases, Metabolic;   Brain Diseases;   Central Nervous System Diseases;   Nervous System Diseases;   Sulfatidosis;   Sphingolipidoses;   Lysosomal Storage Diseases, Nervous System;   Leukoencephalopathies;   Demyelinating Diseases;   Metabolism, Inborn Errors;   Genetic Diseases, Inborn;   Lipidoses;   Lipid Metabolism, Inborn Errors;   Lysosomal Storage Diseases;   Metabolic Diseases;   Lipid Metabolism Disorders
Intervention: Other: Natural History Study of Children With Metachromatic Leukodystrophy
3 Completed The Effect of Fibrate Therapy in Two Patients With Neutral Lipid Storage Disease With Myopathy (NLSDM)
Condition: Neutral Lipid Storage Disease
Intervention: Drug: Fibrate treatment
4 Terminated
Has Results
Hematopoietic Stem Cell Transplantation (HCT) for Inborn Errors of Metabolism
Conditions: Hurler's Syndrome;   Maroteaux-Lamy Syndrome;   Sly Syndrome;   Alpha Mannosidosis;   Fucosidosis;   Aspartylglucosaminuria;   Sphingolipidoses;   Krabbe Disease;   Wolman's Disease;   Niemann-Pick Disease Type B;   Niemann-Pick Disease, Type C
Interventions: Procedure: Stem Cell Transplantation;   Drug: Cyclophosphamide;   Drug: Campath-1H;   Drug: Busulfan
5 Recruiting Biomarker for Gaucher Disease
Conditions: Lysosomal Storage Diseases;   Gaucher Disease;   Sphingolipidoses
Intervention:
6 Recruiting Biomarker for Metachromatic Leukodystrophy Disease
Conditions: Leukodystrophy, Metachromatic;   Hereditary Central Nervous System Demyelinating Diseases;   Brain Diseases, Metabolic, Inborn;   Sphingolipidoses;   Lysosomal Storage Diseases, Nervous System
Intervention:
7 Recruiting Allogeneic Bone Marrow Transplant for Inherited Metabolic Disorders
Conditions: Mucopolysaccharidosis;   Hurler Syndrome;   Hunter Syndrome;   Maroteaux-Lamy Syndrome;   Sly Syndrome;   Alpha Mannosidosis;   Fucosidosis;   Aspartylglucosaminuria;   Adrenoleukodystrophy (ALD);   Globoid Cell Leukodystrophy (GLD);   Krabbe Disease;   Metachromatic Leukodystrophy (MLD);   Sphingolipidoses;   Peroxisomal Disorders
Interventions: Drug: Campath-1H;   Drug: Cyclophosphamide;   Drug: Busulfan;   Procedure: Allogeneic stem cell transplantation;   Drug: Cyclosporine A;   Drug: Mycophenolate Mofetil
8 Active, not recruiting A Clinical Study to Evaluate the Safety,Tolerability and PK of ZYT1, Following Oral Administration in Healthy Volunteers
Conditions: Obesity;   Lipid Disorders
Interventions: Drug: ZYT1;   Drug: Placebo tablets
9 Active, not recruiting Physical Activity and Nutrition in Children Study
Conditions: Overweight;   Glucose Metabolism Disorders;   Lipid Metabolism Disorders;   Blood Pressure;   Fitness
Intervention: Behavioral: lifestyle counseling
10 Completed
Has Results
Lipid Management in Clinical Practice (MK-0524A-115)
Condition: Lipid Metabolism Disorder
Intervention:
11 Completed Regulation of Lipoprotein Transport in Metabolic Syndrome
Conditions: Obesity;   Lipid Disorders;   Cardiovascular Disease
Interventions: Drug: GW501516;   Drug: placebo pill
12 Completed Pharmacological Regulation of Fat Transport in Metabolic Syndrome
Conditions: Obesity;   Lipid Disorders;   Hypertriglyceridemia;   Cardiovascular Disease
Intervention: Drug: Atorvastatin and fenofibrate
13 Recruiting Familial Hypercholesterolemia Canada / Hypercholesterolemie Familiale Canada
Conditions: Familial Hypercholesterolemia;   Lipid Disorder
Intervention:
14 Active, not recruiting An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemia
Conditions: Lipid Metabolism, Inborn Errors;   Hypercholesterolemia, Autosomal Dominant;   Hyperlipidemias;   Metabolic Diseases;   Hyperlipoproteinemia Type II;   Metabolism, Inborn Errors;   Genetic Diseases, Inborn;   Infant, Newborn, Diseases;   Metabolic Disorder;   Congenital Abnormalities;   Hypercholesterolemia;   Hyperlipoproteinemias;   Dyslipidemias;   Lipid Metabolism Disorders
Intervention: Drug: mipomersen sodium
15 Active, not recruiting Pilot Study To Assess CAT-2003 in Patients With Severe Hypertriglyceridemia
Conditions: Hyperlipidemias;   Hypertriglyceridemia;   Dyslipidemias;   Lipid Metabolism Disorders;   Metabolic Diseases
Interventions: Drug: CAT-2003;   Drug: Placebo
16 Active, not recruiting Study of the Long-term Effects of Exercise on Heath Indicators in Older People
Conditions: Hypertension With Complications and Secondary Hypertension;   Overweight and Obesity;   Lipid Metabolism Disorders;   Sarcopenia;   Osteoporosis;   Personal Satisfaction
Intervention: Behavioral: Exercise training
17 Recruiting Influence of Caloric Restriction and Resveratrol in the Sirtuin System in Women and Men Aged 55 to 65 Years
Conditions: Vascular System Injuries;   Lipid Metabolism Disorders;   Endothelial Disfunction
Interventions: Drug: Resveratrol;   Behavioral: Caloric restriction
18 Completed
Has Results
Safety and Efficacy Study of ISIS 301012 (Mipomersen) Administration in High Risk Statin Intolerant Subjects
Conditions: Metabolic Diseases;   Hyperlipidemias;   Metabolic Disorder;   Hypercholesterolemia;   Dyslipidemias;   Lipid Metabolism Disorders
Interventions: Drug: mipomersen;   Drug: placebo
19 Completed Open Label Study Evaluating The Use Of Combination Therapy Of Ezetimibe And Statins In Patients With Dyslipidemia In Colombia
Condition: Lipid Metabolism Disorder
Intervention: Drug: ezetimibe
20 Recruiting Effect of Age on Glucose and Lipid Metabolism
Conditions: Glucose Metabolism Disorders;   Lipid Metabolism Disorders;   Metabolic Diseases
Intervention: Behavioral: Aerobic Exercise

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Indicates status has not been verified in more than two years