47 studies found for:    "Severe combined immunodeficiency"
Show Display Options
RSS Create an RSS feed from your search for:
"Severe combined immunodeficiency"
Need help? See RSS Feeds
Choose a feed type:
Show studies first received on any dateShow studies that were first received in the last 14 days
Show studies last updated date on any dateShow studies that were added or modified in the last 14 days
Rank Status Study
1 Completed Transplantation of Hematopoietic Cells in Children With Severe Combined Immunodeficiency Syndrome
Condition: Severe Combined Immunodeficiency
Interventions: Procedure: Stem cell transplant;   Drug: Filgrastim, Alemtuzumab;   Device: Miltenyi CliniMACS
2 Not yet recruiting Generalized Neonatal Screening of Severe Combined Immunodeficiencies
Condition: Severe Combined Immunodeficiency, Atypical
Intervention: Biological: SCID screening
3 Recruiting Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
Conditions: X-linked Severe Combined Immunodeficiency;   XSCID;   SCID-X1;   Gamma C-Deficient SCID
Intervention: Other: Gene Transfer
4 Active, not recruiting Gene Therapy for X-linked Severe Combined Immunodeficiency
Condition: X-linked Severe Combined Immunodeficiency
Intervention: Other: Gene transfer
5 Completed Treatment for Growth Failure in Patients With X-Linked Severe Combined Immunodeficiency: Phase 2 Study of Insulin-Like Growth Factor-1
Conditions: Growth Failure;   X-linked Severe Combined Immunodeficiency (XSCID);   Growth Hormone Resistence
Interventions: Drug: Increlex;   Procedure: Arginine Provocation Test;   Procedure: Clonidine Provocation Test;   Procedure: IGF-1 Generation Test;   Drug: IVIG;   Procedure: Haplo-Identical Bone Marrow Transplant
6 Completed Stem Cell Gene Therapy to Treat X-Linked Severe Combined Immunodeficiency (XSCID)
Condition: Severe Combined Immunodeficiency
Intervention: Drug: Gene-Transduced Autologous CD34+ Stem Cells
7 Not yet recruiting Clinical Characteristics and Genetic Profiles of Severe Combined Immunodeficiency in China
Condition: Severe Combined Immunodeficiency
Intervention: Genetic: gene sequencing
8 Active, not recruiting Total-Body Irradiation Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Severe Combined Immunodeficiency Undergoing Donor Bone Marrow Transplant
Conditions: Immune System Disorder;   Severe Combined Immunodeficiency
Interventions: Drug: cyclosporine;   Drug: mycophenolate mofetil;   Radiation: total-body irradiation;   Procedure: allogeneic bone marrow transplantation;   Procedure: nonmyeloablative allogeneic hematopoietic stem cell transplantation;   Other: laboratory biomarker analysis
9 Recruiting Gene Transfer for X-Linked Severe Combined Immunodeficiency in Newly Diagnosed Infants
Condition: Severe Combined Immunodeficiency Disease, X-linked
Interventions: Genetic: CL20-4i-EF/a-hyc-OPT;   Drug: Busulfan
10 Recruiting Autologous Transplant of EFS-ADA Modified Bone Marrow Cells for ADA-Deficient Severe Combined Immunodeficiency (SCID)
Condition: Severe Combined Immunodeficiency Due to Adenosine Deaminase Deficiency
Intervention: Genetic: EFS-ADA transduced CD34+ cells from the bone marrow
11 Recruiting Gene Transfer for Severe Combined Immunodeficiency, X-linked (SCID-X1) Using a Self-inactivating (SIN) Gammaretroviral Vector
Condition: Severe Combined Immunodeficiency
Intervention: Biological: Gene transfer
12 Completed Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency: A Natural History Study
Condition: Severe Combined Immunodeficiency
Interventions: Drug: ADA PBSC;   Drug: ADA Umbilical Cord Blood Cells;   Drug: Transduced Lymphocytes
13 Unknown  Gene Therapy for X-linked Severe Combined Immunodeficiency (SCID-X1)
Condition: X-linked Severe Combined Immunodeficiency
Intervention: Genetic: Single infusion of autologous CD34+ cells transduced with the self-inactivating (SIN) gammaretroviral vector pSRS11.EFS.IL2RG.pre
14 Recruiting Sirolimus Prophylaxis for aGVHD in TME SCID
Conditions: Severe Combined Immunodeficiency;   Transplacental Maternal Engraftment;   Stem Cell Transplant
Intervention: Drug: Sirolimus
15 Terminated
Has Results
Allogeneic SCT Of Pts With SCID And Other Primary Immunodeficiency Disorders
Conditions: Severe Combined Immunodeficiency Disease;   Severe Primary Immunodeficiency Disorder;   Undefined T Cell Deficiency Disorder;   Wiskott-Aldrick Syndrome
Interventions: Biological: Campath -1H;   Drug: Fludarabine;   Biological: Anti-CD45;   Procedure: Stem cell infusion
16 Completed Newborn Screening for Severe Combined Immunodeficiency (SCID) in a High-Risk Population
Conditions: Severe Combined Immunodeficiency;   T Cell Lymphocytopenia
Intervention:
17 Completed Influences on Female Adolescents' Decisions Regarding Testing for Carrier Status of XSCID
Condition: Severe Combined Immunodeficiency
Intervention:
18 Terminated Hematopoietic Stem Cell Transplantation (HSCT) for Children With SCID Utilizing Alemtuzumab, Plerixafor & Filgrastim
Condition: Severe Combined Immunodeficiency
Interventions: Drug: Transplant Conditioning with Mobilization Only;   Drug: Transplant Conditioning with Mobilization and Alemtuzumab
19 Active, not recruiting MND-ADA Transduction of CD34+ Cells From Children With ADA-SCID
Condition: Severe Combined Immunodeficiency
Intervention: Biological: ADA gene transfer
20 Recruiting Establishing Fibroblast-Derived Cell Lines From Skin Biopsies of Patients With Immunodeficiency or Immunodysregulation Disorders
Conditions: Lymphohistiocytosis, Hemophagocytic;   Common Variable Immunodeficiency;   Severe Combined Immunodeficiency
Intervention:

   Previous Page Studies Shown (1-20) Next Page (21-40) Show next page of results    Last Page
Indicates status has not been verified in more than two years