56 studies found for:    "Optic neuritis"
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Rank Status Study
21 Unknown  Longitudinal Optic Neuritis Study (LONS)
Conditions: Multiple Sclerosis;   Optic Neuritis
Interventions: Drug: Methylprednisolone;   Drug: Prednisone
22 Recruiting Amiloride Hydrochlorothiazide as Treatment of Acute Inflammation of the Optic Nerve
Condition: Acute Autoimmune Optic Neuritis
Interventions: Drug: Amiloride hydrochlorothiazide;   Drug: Sugar pill
23 Withdrawn Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event.
Conditions: Demyelinating Disorders;   Multiple Sclerosis;   Optic Neuritis;   Myelitis;   Neuritis
Interventions: Drug: interferon beta 1a;   Drug: methotrexate;   Drug: methylprednisolone
24 Recruiting Manganese-Enhanced Magnetic Resonance Imaging in Healthy Volunteers and People With Multiple Sclerosis
Conditions: Multiple Sclerosis;   Optic Neuritis
Intervention: Drug: Mangafodipir (Teslascan)
25 Enrolling by invitation Biobank For MS And Other Demyelinating Diseases
Conditions: Multiple Sclerosis;   Transverse Myelitis;   Neuromyelitis Optica;   Acute Disseminated Encephalomyelitis;   Optic Neuritis
Intervention:
26 Recruiting A Longitudinal Study of Neuromyelitis Optica and Transverse Myelitis
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder;   Transverse Myelitis;   Optic Neuritis
Intervention:
27 Completed Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis
Conditions: Multiple Sclerosis;   Optic Neuritis;   Transverse Myelitis;   Acute Brainstem/Cerebellar Syndrome
Intervention: Drug: interferon beta 1a 30 ug IM once weekly
28 Recruiting Natural History of Optic Neuritis
Condition: Multiple Sclerosis
Intervention:
29 Recruiting A Phase IV Trial of Neuroprotection With ACTH in Acute Optic Neuritis
Condition: Multiple Sclerosis
Interventions: Drug: ACTHAR Gel (ACTH);   Drug: IV steroids with oral taper
30 Completed Optical Coherence Tomography in Multiple Sclerosis Patients
Conditions: Multiple Sclerosis;   Optic Neuritis
Intervention:
31 Recruiting MOdification of VIsual Outcomes After Optic Neuritis in CIS or MS by Gilenya (MOVING Study)
Condition: Multiple Sclerosis
Interventions: Drug: Verum arm receiving Gilenya®;   Drug: Active Comparator receiving Extavia®
32 Completed Safety and Tolerability of Rituximab in Neuromyelitis Optica
Condition: Neuromyelitis Optica
Intervention: Drug: Rituximab
33 Recruiting Efficacy of Bevacizumab (Avastin) in Treatment of Acute NMO Exacerbations
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder
Intervention: Drug: Bevacizumab
34 Recruiting Pilot Study of alpha1-antitrypsin to Treat Neuromyelitis Optica Relapses
Condition: Neuromyelitis Optica
Interventions: Drug: Alpha1-antitrypsin;   Drug: methylprednisolone
35 Not yet recruiting An Open Label Extension Trial of Eculizumab in Relapsing NMO Patients
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder
Intervention: Biological: eculizumab
36 Recruiting A Double Blind Trial To Evaluate The Safety And Efficacy Of Eculizumab In Relapsing NMO Patients
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder
Intervention: Drug: Eculizumab
37 Unknown  Evaluation of Neural Loss in Multiple Sclerosis and Neuromyelitis Optica Using High Resolution Oct
Conditions: Multiple Sclerosis;   Neuromyelitis Optica
Intervention:
38 Unknown  Optical Coherence Tomography: Glatiramer in Clinically Isolated Syndrome or Early Relapsing Remitting Multiple Sclerosis (MS)
Condition: Multiple Sclerosis
Intervention: Drug: glatiramer acetate
39 Completed
Has Results
C1-esterase Inhibitor (Cinryze) for Acute Treatment of Neuromyelitis Optica Exacerbation
Condition: Neuromyelitis Optica
Intervention: Drug: C1-esterase inhibitor (Cinryze)
40 Recruiting Hematopoietic Stem Cell Transplant in Devic's Disease
Condition: Devic's Disease
Intervention: Procedure: Hematopoietic stem cell transplantation

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Indicates status has not been verified in more than two years