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13 studies found for:    "Nevoid basal cell carcinoma syndrome"

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Rank Status Study
1 Recruiting Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome
Conditions: Basal Cell Carcinoma;   Gorlin Syndrome;   Nevoid Basal Cell Carcinoma Syndrome
Interventions: Drug: LDE225;   Drug: Placebo
2 Active, not recruiting The Purpose of This Study is to Determine The Efficacy and Safety of a Systemic Hedgehog Pathway Antagonist (GDC-0449) in Patients With Basal Cell Nevus Syndrome (BCNS)
Conditions: Basal Cell Nevus Syndrome;   Gorlin Syndrome
Intervention: Drug: GDC-0449
3 Terminated Two Studies to Determine if Verteporfin PDT is Effective & Safe in Treating Multiple Basal Cell Carcinoma of the Skin.
Conditions: Basal Cell Carcinoma;   Nevoid Basal Cell Carcinoma Syndrome;   Gorlin Syndrome
Intervention: Drug: verteporfin PDT
4 Completed A Trial to Evaluate the Safety, Local Tolerability, Pharmacokinetics and Pharmacodynamics of LDE225 on Skin Basal Cell Carcinomas in Gorlin Syndrome Patients
Condition: Treatment for Basal Cell Carcinomas (BCCs) in Gorlin Syndrome Patients
Interventions: Drug: Placebo;   Drug: LDE225;   Drug: LDE225 0.25%;   Drug: LDE225 0.75%
5 Recruiting Trial Comparing the Effects of Intermittent Vismodegib Versus Photodynamic Therapy in Patients With Multiple Basal Cell Carcinomas
Conditions: Basal Cell Nevus Syndrome;   Gorlin's Syndrome
Interventions: Drug: GDC-0449;   Procedure: Aminolevulinic acid %20 topical solution + blue light
6 Completed Use of an SPF30 Sunscreen and an After-sun-lotion in Skin Cancer Risk Patients
Conditions: Skin Cancer;   Xeroderma Pigmentosum;   Basal Cell Nevus Syndrome
Intervention:
7 Unknown † Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy Participants
Conditions: Neoplastic Syndrome;   Non-Melanomatous Skin Cancer
Interventions: Drug: sirolimus;   Genetic: comparative genomic hybridization;   Genetic: gene expression analysis;   Genetic: microarray analysis;   Genetic: protein expression analysis;   Genetic: proteomic profiling;   Other: laboratory biomarker analysis;   Other: mass spectrometry;   Procedure: biopsy
8 Completed Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the Face
Conditions: Neoplastic Syndrome;   Non-melanomatous Skin Cancer
Intervention: Drug: tazarotene
9 Completed Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the Chest and Back
Conditions: Neoplastic Syndrome;   Non-melanomatous Skin Cancer
Interventions: Drug: tazarotene;   Other: placebo
10 Completed Celecoxib in Preventing Basal Cell Carcinoma in Patients With Basal Cell Nevus Syndrome
Condition: Non-melanomatous Skin Cancer
Intervention: Drug: celecoxib
11 Completed Isotretinoin in Preventing Skin Cancer
Conditions: Melanoma (Skin);   Non-Melanomatous Skin Cancer
Intervention: Drug: isotretinoin
12 Completed A Clinical Trial of Dermacorder for Detecting Malignant Skin Lesions
Condition: Basal Cell Carcinoma
Intervention:
13 Completed Development of a Nanosecond Pulsed Electric Field System to Treat Skin Cancer
Condition: Basal Cell Carcinomas
Intervention: Device: PulseCure pulse generator and Derm-pulse electrode
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† Indicates status has not been verified in more than two years