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125 studies found for:    "Neurotoxicity syndromes"
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Rank Status Study
1 Terminated A Pilot Study of Dextromethorphan for the Prevention and Treatment of Methotrexate Neurotoxicity
Condition: Neurotoxicity Syndromes
Intervention: Drug: Dextromethorphan
2 Unknown  Biomarkers in Predicting Neurotoxicity in Patients With Colorectal Cancer Receiving Oxaliplatin
Conditions: Chemotherapeutic Agent Toxicity;   Colorectal Cancer;   Neurotoxicity
Interventions: Drug: FOLFOX regimen;   Drug: fluorouracil;   Drug: leucovorin calcium;   Drug: oxaliplatin;   Genetic: gene expression analysis;   Genetic: protein expression analysis;   Genetic: proteomic profiling;   Other: laboratory biomarker analysis;   Other: pharmacogenomic studies
3 Unknown  Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy
Conditions: Chemotherapeutic Agent Toxicity;   Colorectal Cancer;   Neuropathy;   Neurotoxicity
Interventions: Drug: calcium gluconate;   Drug: magnesium sulfate;   Other: placebo
4 Completed
Has Results
Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity Caused By Oxaliplatin in Patients Receiving Combination Chemotherapy for Stage II, Stage III, or Stage IV Colorectal Cancer That Has Been Completely Removed By Surgery
Conditions: Colorectal Cancer;   Neurotoxicity
Interventions: Drug: calcium gluconate;   Drug: magnesium sulfate;   Other: placebo
5 Recruiting Study to Assess Prevention of Oxaliplatin-induced Neurotoxicity Through Vitamin D Pathway
Condition: Neurotoxicity
Intervention: Drug: Vitamin D3
6 Completed Protective Effect of Mangafodipir Against Oxaliplatin Neurotoxicity
Conditions: Neurotoxic Disorders;   Cancer
Intervention: Drug: Mangafodipir
7 Terminated Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial Cancer
Conditions: Cervical Cancer;   Endometrial Cancer;   Fallopian Tube Cancer;   Neurotoxicity;   Ovarian Cancer;   Primary Peritoneal Cavity Cancer;   Sarcoma
Interventions: Drug: amifostine trihydrate;   Drug: cisplatin;   Drug: paclitaxel
8 Recruiting Heavy Metal Exposure in Predicting Peripheral Neuropathy in Patients With Stage I-III Breast Cancer Undergoing Chemotherapy
Conditions: Male Breast Cancer;   Neurotoxicity;   Peripheral Neuropathy;   Stage IA Breast Cancer;   Stage IB Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
Interventions: Other: laboratory biomarker analysis;   Other: questionnaire administration
9 Unknown  Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
Conditions: Neurotoxicity Syndromes;   Pain;   Peripheral Neuropathy;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: duloxetine hydrochloride;   Other: placebo
10 Active, not recruiting Hearing Loss and Dizziness in Patients Receiving Oxaliplatin for Solid Tumors
Conditions: Neurotoxicity;   Unspecified Adult Solid Tumor, Protocol Specific
Intervention: Procedure: management of therapy complications
11 Recruiting Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma
Conditions: Lymphoma;   Neurotoxicity;   Therapy-related Toxicity
Interventions: Biological: rituximab;   Drug: bendamustine hydrochloride;   Drug: bortezomib;   Drug: lenalidomide
12 Active, not recruiting Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors
Conditions: Cognitive/Functional Effects;   Metastatic Cancer;   Neurotoxicity;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: memantine hydrochloride;   Other: placebo;   Radiation: radiation therapy
13 Withdrawn Acetyl-L-Carnitine Hydrochloride in Preventing Peripheral Neuropathy in Patients With Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer Undergoing Chemotherapy
Conditions: Fallopian Tube Cancer;   Fatigue;   Neuropathy;   Neurotoxicity;   Ovarian Cancer;   Pain;   Primary Peritoneal Cavity Cancer
Interventions: Dietary Supplement: acetyl-L-carnitine hydrochloride;   Drug: carboplatin;   Drug: cisplatin;   Drug: paclitaxel;   Other: placebo
14 Terminated Molecular-Genetic Mechanisms Associated With Chemotherapy-Induced Nerve Damage
Conditions: Peripheral Neuropathic Pain;   Neurotoxicity;   Cancer
Intervention:
15 Terminated Adderall XR Compared With Concerta in Treating Young Cancer Patients With Memory, Attention, and Depression
Conditions: Depression;   Neurotoxicity;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: Adderall-XR®;   Drug: Concerta®
16 Completed Nerve Changes in Patients Who Are Undergoing Chemotherapy or Biological Therapy for Cancer
Conditions: Neurotoxicity;   Unspecified Adult Solid Tumor, Protocol Specific
Intervention: Procedure: management of therapy complications
17 Completed Gabapentin in Treating Peripheral Neuropathy in Cancer Patients Undergoing Chemotherapy
Conditions: Neurotoxicity;   Pain
Interventions: Drug: gabapentin;   Procedure: quality-of-life assessment
18 Completed Dimesna in Treating Patients With Solid Tumors Who Are Undergoing Treatment With Cisplatin and Paclitaxel
Conditions: Head and Neck Cancer;   Lung Cancer;   Neurotoxicity;   Ovarian Cancer
Interventions: Drug: cisplatin;   Drug: dimesna;   Drug: paclitaxel
19 Unknown  Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Treated on Clinical Trial CCLG-GC-1979-01 or CCLG-GC-1989-01
Conditions: Childhood Germ Cell Tumor;   Extragonadal Germ Cell Tumor;   Gastrointestinal Complications;   Infertility;   Long-term Effects Secondary to Cancer Therapy in Children;   Neurotoxicity;   Ovarian Cancer;   Pulmonary Complications;   Sexual Dysfunction;   Urinary Complications
Interventions: Procedure: assessment of therapy complications;   Procedure: quality-of-life assessment
20 Recruiting Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery
Conditions: Cognitive/Functional Effects;   Metastatic Cancer;   Neurotoxicity;   Radiation Toxicity;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Radiation: stereotactic radiosurgery;   Radiation: whole-brain radiation therapy

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Indicates status has not been verified in more than two years