125 studies found for:    "Neurotoxicity syndromes"
Show Display Options
Rank Status Study
1 Terminated A Pilot Study of Dextromethorphan for the Prevention and Treatment of Methotrexate Neurotoxicity
Condition: Neurotoxicity Syndromes
Intervention: Drug: Dextromethorphan
2 Unknown  Biomarkers in Predicting Neurotoxicity in Patients With Colorectal Cancer Receiving Oxaliplatin
Conditions: Chemotherapeutic Agent Toxicity;   Colorectal Cancer;   Neurotoxicity
Interventions: Drug: FOLFOX regimen;   Drug: fluorouracil;   Drug: leucovorin calcium;   Drug: oxaliplatin;   Genetic: gene expression analysis;   Genetic: protein expression analysis;   Genetic: proteomic profiling;   Other: laboratory biomarker analysis;   Other: pharmacogenomic studies
3 Unknown  Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy
Conditions: Chemotherapeutic Agent Toxicity;   Colorectal Cancer;   Neuropathy;   Neurotoxicity
Interventions: Drug: calcium gluconate;   Drug: magnesium sulfate;   Other: placebo
4 Completed
Has Results
Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity Caused By Oxaliplatin in Patients Receiving Combination Chemotherapy for Stage II, Stage III, or Stage IV Colorectal Cancer That Has Been Completely Removed By Surgery
Conditions: Colorectal Cancer;   Neurotoxicity
Interventions: Drug: calcium gluconate;   Drug: magnesium sulfate;   Other: placebo
5 Recruiting Study to Assess Prevention of Oxaliplatin-induced Neurotoxicity Through Vitamin D Pathway
Condition: Neurotoxicity
Intervention: Drug: Vitamin D3
6 Completed Protective Effect of Mangafodipir Against Oxaliplatin Neurotoxicity
Conditions: Neurotoxic Disorders;   Cancer
Intervention: Drug: Mangafodipir
7 Terminated Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial Cancer
Conditions: Cervical Cancer;   Endometrial Cancer;   Fallopian Tube Cancer;   Neurotoxicity;   Ovarian Cancer;   Primary Peritoneal Cavity Cancer;   Sarcoma
Interventions: Drug: amifostine trihydrate;   Drug: cisplatin;   Drug: paclitaxel
8 Recruiting Heavy Metal Exposure in Predicting Peripheral Neuropathy in Patients With Stage I-III Breast Cancer Undergoing Chemotherapy
Conditions: Male Breast Cancer;   Neurotoxicity;   Peripheral Neuropathy;   Stage IA Breast Cancer;   Stage IB Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
Interventions: Other: laboratory biomarker analysis;   Other: questionnaire administration
9 Unknown  Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
Conditions: Neurotoxicity Syndromes;   Pain;   Peripheral Neuropathy;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: duloxetine hydrochloride;   Other: placebo
10 Completed
Has Results
Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer
Conditions: Kidney Cancer;   Leukemia;   Lymphoma;   Neurotoxicity;   Peripheral Neuropathy;   Sarcoma
Interventions: Drug: glutamic acid;   Other: placebo
11 Unknown  Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer
Conditions: Chemotherapeutic Agent Toxicity;   Fallopian Tube Cancer;   Neurotoxicity;   Ovarian Cancer;   Pain;   Peripheral Neuropathy;   Primary Peritoneal Cavity Cancer
Interventions: Drug: carboplatin;   Drug: glutathione;   Drug: paclitaxel;   Other: placebo
12 Active, not recruiting Bortezomib, Thalidomide, and Dexamethasone After Melphalan and Stem Cell Transplant in Treating Patients With Stage I-III Multiple Myeloma
Conditions: Multiple Myeloma and Plasma Cell Neoplasm;   Neurotoxicity
Interventions: Drug: bortezomib;   Drug: dexamethasone;   Drug: melphalan;   Drug: thalidomide;   Genetic: cytogenetic analysis;   Genetic: fluorescence in situ hybridization;   Other: laboratory biomarker analysis;   Other: questionnaire administration;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: peripheral blood stem cell transplantation
13 Recruiting Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma
Conditions: Lymphoma;   Neurotoxicity;   Therapy-related Toxicity
Interventions: Biological: rituximab;   Drug: bendamustine hydrochloride;   Drug: bortezomib;   Drug: lenalidomide
14 Active, not recruiting Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors
Conditions: Cognitive/Functional Effects;   Metastatic Cancer;   Neurotoxicity;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: memantine hydrochloride;   Other: placebo;   Radiation: radiation therapy
15 Completed Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201
Conditions: Long-term Effects Secondary to Cancer Therapy in Children;   Neurotoxicity
Intervention: Procedure: management of therapy complications
16 Terminated Adderall XR Compared With Concerta in Treating Young Cancer Patients With Memory, Attention, and Depression
Conditions: Depression;   Neurotoxicity;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: Adderall-XR®;   Drug: Concerta®
17 Unknown  Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
Conditions: Neurotoxicity;   Pain;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: lamotrigine;   Procedure: quality-of-life assessment
18 Completed Amifostine in Treating Peripheral Neuropathy Caused by Paclitaxel in Patients With Solid Tumors
Conditions: Breast Cancer;   Lung Cancer;   Neurotoxicity;   Ovarian Cancer;   Prostate Cancer;   Unspecified Adult Solid Tumor, Protocol Specific
Intervention: Drug: Amifostine
19 Completed S0715: Acetyl-L-Carnitine in Preventing Neuropathy in Women With Stage I, Stage II, or Stage IIIA Breast Cancer Undergoing Chemotherapy
Conditions: Breast Cancer;   Chemotherapeutic Agent Toxicity;   Fatigue;   Neuropathy;   Neurotoxicity
Interventions: Dietary Supplement: acetyl-L-carnitine hydrochloride;   Other: placebo
20 Active, not recruiting Topical Amitriptyline and Ketamine Cream in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
Conditions: Neurotoxicity;   Pain;   Peripheral Neuropathy;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: ketamine/amitriptyline NP-H cream;   Other: placebo

   Previous Page Studies Shown (1-20) Next Page (21-40) Show next page of results    Last Page
Indicates status has not been verified in more than two years