125 studies found for:    "Neurotoxicity syndromes"
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Rank Status Study
1 Terminated A Pilot Study of Dextromethorphan for the Prevention and Treatment of Methotrexate Neurotoxicity
Condition: Neurotoxicity Syndromes
Intervention: Drug: Dextromethorphan
2 Unknown  Biomarkers in Predicting Neurotoxicity in Patients With Colorectal Cancer Receiving Oxaliplatin
Conditions: Chemotherapeutic Agent Toxicity;   Colorectal Cancer;   Neurotoxicity
Interventions: Drug: FOLFOX regimen;   Drug: fluorouracil;   Drug: leucovorin calcium;   Drug: oxaliplatin;   Genetic: gene expression analysis;   Genetic: protein expression analysis;   Genetic: proteomic profiling;   Other: laboratory biomarker analysis;   Other: pharmacogenomic studies
3 Unknown  Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy
Conditions: Chemotherapeutic Agent Toxicity;   Colorectal Cancer;   Neuropathy;   Neurotoxicity
Interventions: Drug: calcium gluconate;   Drug: magnesium sulfate;   Other: placebo
4 Completed
Has Results
Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity Caused By Oxaliplatin in Patients Receiving Combination Chemotherapy for Stage II, Stage III, or Stage IV Colorectal Cancer That Has Been Completely Removed By Surgery
Conditions: Colorectal Cancer;   Neurotoxicity
Interventions: Drug: calcium gluconate;   Drug: magnesium sulfate;   Other: placebo
5 Recruiting Study to Assess Prevention of Oxaliplatin-induced Neurotoxicity Through Vitamin D Pathway
Condition: Neurotoxicity
Intervention: Drug: Vitamin D3
6 Completed Protective Effect of Mangafodipir Against Oxaliplatin Neurotoxicity
Conditions: Neurotoxic Disorders;   Cancer
Intervention: Drug: Mangafodipir
7 Terminated Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial Cancer
Conditions: Cervical Cancer;   Endometrial Cancer;   Fallopian Tube Cancer;   Neurotoxicity;   Ovarian Cancer;   Primary Peritoneal Cavity Cancer;   Sarcoma
Interventions: Drug: amifostine trihydrate;   Drug: cisplatin;   Drug: paclitaxel
8 Recruiting Heavy Metal Exposure in Predicting Peripheral Neuropathy in Patients With Stage I-III Breast Cancer Undergoing Chemotherapy
Conditions: Male Breast Cancer;   Neurotoxicity;   Peripheral Neuropathy;   Stage IA Breast Cancer;   Stage IB Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
Interventions: Other: laboratory biomarker analysis;   Other: questionnaire administration
9 Unknown  Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
Conditions: Neurotoxicity Syndromes;   Pain;   Peripheral Neuropathy;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: duloxetine hydrochloride;   Other: placebo
10 Active, not recruiting Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer
Conditions: Breast Cancer;   Chemotherapeutic Agent Toxicity;   Cognitive/Functional Effects;   Fatigue;   Long-term Effects Secondary to Cancer Therapy in Adults;   Neurotoxicity;   Psychosocial Effects of Cancer and Its Treatment
Interventions: Biological: trastuzumab;   Drug: aromatase inhibition therapy;   Drug: carboplatin;   Drug: cyclophosphamide;   Drug: docetaxel;   Drug: doxorubicin hydrochloride;   Other: metabolic assessment;   Other: questionnaire administration;   Other: study of socioeconomic and demographic variables;   Procedure: cognitive assessment;   Procedure: positron emission tomography;   Radiation: fludeoxyglucose F 18
11 Completed Nerve Changes in Patients Who Are Undergoing Chemotherapy or Biological Therapy for Cancer
Conditions: Neurotoxicity;   Unspecified Adult Solid Tumor, Protocol Specific
Intervention: Procedure: management of therapy complications
12 Terminated Adderall XR Compared With Concerta in Treating Young Cancer Patients With Memory, Attention, and Depression
Conditions: Depression;   Neurotoxicity;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: Adderall-XR®;   Drug: Concerta®
13 Recruiting Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma
Conditions: Chemotherapeutic Agent Toxicity;   Cognitive/Functional Effects;   Lymphoma;   Neurotoxicity;   Radiation Toxicity
Interventions: Biological: rituximab;   Drug: cytarabine;   Drug: methotrexate;   Drug: procarbazine hydrochloride;   Drug: vincristine sulfate;   Radiation: whole-brain radiation therapy
14 Completed Combination Chemotherapy in Treating Patients With Metastatic Ovarian Cancer or Non-small Cell Lung Cancer
Conditions: Lung Cancer;   Neurotoxicity;   Ovarian Cancer
Interventions: Drug: amifostine trihydrate;   Drug: carboplatin;   Drug: paclitaxel
15 Completed Nerve Function in Older Diabetic Patients Who Are Undergoing Chemotherapy for Metastatic Solid Tumors
Conditions: Neurotoxicity;   Unspecified Adult Solid Tumor, Protocol Specific
Intervention: Procedure: management of therapy complications
16 Completed
Has Results
Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer
Conditions: Kidney Cancer;   Leukemia;   Lymphoma;   Neurotoxicity;   Peripheral Neuropathy;   Sarcoma
Interventions: Drug: glutamic acid;   Other: placebo
17 Completed Gabapentin in Treating Peripheral Neuropathy in Cancer Patients Undergoing Chemotherapy
Conditions: Neurotoxicity;   Pain
Interventions: Drug: gabapentin;   Procedure: quality-of-life assessment
18 Completed Dimesna in Treating Patients With Solid Tumors Who Are Undergoing Treatment With Cisplatin and Paclitaxel
Conditions: Head and Neck Cancer;   Lung Cancer;   Neurotoxicity;   Ovarian Cancer
Interventions: Drug: cisplatin;   Drug: dimesna;   Drug: paclitaxel
19 Unknown  Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
Conditions: Chronic Myeloproliferative Disorders;   Leukemia;   Lymphoma;   Lymphoproliferative Disorder;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Neoplasms;   Neurotoxicity;   Pain;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: baclofen/amitriptyline/ketamine gel;   Other: placebo
20 Active, not recruiting
Has Results
Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain
Conditions: Brain and Central Nervous System Tumors;   Cognitive/Functional Effects;   Long-term Effects Secondary to Cancer Therapy in Children;   Neurotoxicity;   Psychosocial Effects of Cancer and Its Treatment;   Radiation Toxicity
Intervention: Drug: Donepezil

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Indicates status has not been verified in more than two years