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76 studies found for:    "Neurofibromatosis"

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Rank Status Study
1 Active, not recruiting Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas
Conditions: Neurofibromatosis Type 1;   Plexiform Neurofibroma;   Neurofibromatoses
Intervention: Drug: RAD001: Everolimus
2 Completed Adaptation and Quality of Life Among Adults With Neurofibromatosis Type I
Conditions: Neurofibromatosis Type 1;   Von Recklinghausen Disease;   NF1
Intervention:
3 Recruiting AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors
Conditions: Neurofibromatosis 1;   Neurofibromatosis Type 1;   NF 1;   Neurofibroma, Plexiform
Intervention: Drug: AZD6244 hyd sulfate
4 Recruiting Neurofibromatosis Type 1 Patient Registry
Condition: Neurofibromatosis Type 1
Intervention:
5 Completed
Has Results 		R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas
Conditions: Neurofibroma, Plexiform;   Neurofibromatosis Type I
Interventions: Drug: tipifarnib;   Other: placebo
6 Recruiting Whole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in Neurofibromatosis
Conditions: Whole Body Imaging;   Magnetic Resonance Imaging;   Neurofibromatosis 1;   Diffusion Magnetic Resonance Imaging;   Peripheral Nerve Sheath Tumors, Malignant
Intervention: Other: Additional imaging or surgery
7 Recruiting Modifying Genes in Neurofibromatosis 1
Condition: Neurofibromatosis 1
Intervention: Other: No intervention
8 Suspended PTC299 for Treatment of Neurofibromatosis Type 2
Condition: Neurofibromatosis 2
Intervention: Drug: PTC299
9 Unknown † Neurofibromatosis Type 1 (NF1) and Tibial Dysplasia
Conditions: Neurofibromatosis Type 1;   Tibial Dysplasia
Intervention:
10 Completed Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1
Conditions: Dermal Neurofibromas;   Neurofibromatosis Type 1
Intervention:
11 Active, not recruiting Spinal Abnormalities in Neurofibromatosis Type 1 (NF1)
Condition: Neurofibromatosis Type 1
Intervention:
12 Recruiting Neuropsychological Impairment and Quality of Life in Neurofibromatosis Type 1
Condition: Neurofibromatosis Type 1
Intervention: Other: Neuropsychological examination and quality of life measures
13 Recruiting How Neurofibromatosis Type 1 (NF1) Affects Schoolwork and Self-Esteem
Condition: Neurofibromatosis Type 1
Intervention:
14 Suspended Study of Disease Severity in Adults With Neurofibromatosis Type 1 (NF1)
Condition: Neurofibromatosis Type I
Intervention:
15 Recruiting Natural History Study of Patients With Neurofibromatosis Type I
Conditions: Neurofibromatosis Type 1;   Malignant Peripheral Nerve Sheath Tumor;   Plexiform Neurofibroma;   Optic Glioma;   Neurofibroma
Intervention:
16 Completed Pirfenidone in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas
Conditions: Neurofibromatosis Type 1;   Precancerous Condition
Intervention: Drug: pirfenidone
17 Completed Sirolimus to Treat Plexiform Neurofibromas in Patients With Neurofibromatosis Type I
Conditions: Neurofibromatosis Type 1;   Plexiform Neurofibromas;   Paraspinal Plexiform Neurofibromas
Intervention: Drug: Sirolimus
18 Completed
Has Results 		Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform Neurofibromas
Conditions: Neurofibromatosis 1;   Neurofibroma, Plexiform
Intervention: Drug: Pirfenidone
19 Recruiting Trial to Evaluate the Safety of Lovastatin in Individuals With Neurofibromatosis Type I (NF1)
Condition: Neurofibromatosis 1
Interventions: Drug: Lovastatin;   Drug: placebo pill
20 Recruiting A Randomized Placebo-Controlled Study of Lovastatin in Children With Neurofibromatosis Type 1
Condition: Neurofibromatosis Type 1
Interventions: Drug: Lovastatin ™;   Device: placebo
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† Indicates status has not been verified in more than two years