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395 studies found for:    "Neuroblastoma"

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Rank Status Study
1 Recruiting Vorinostat and Isotretinoin in Treating Patients With High-Risk Refractory or Recurrent Neuroblastoma
Conditions: Disseminated Neuroblastoma;   Localized Unresectable Neuroblastoma;   Recurrent Neuroblastoma;   Regional Neuroblastoma;   Stage 4S Neuroblastoma
Interventions: Drug: vorinostat;   Drug: isotretinoin;   Other: diagnostic laboratory biomarker analysis;   Other: pharmacological study
2 Active, not recruiting Study of Ch14.18 in Young Patients With High-Risk Neuroblastoma
Conditions: Disseminated Neuroblastoma;   Localized Resectable Neuroblastoma;   Localized Unresectable Neuroblastoma;   Neurotoxicity;   Pain;   Regional Neuroblastoma;   Stage 4S Neuroblastoma;   Therapy-related Toxicity
Interventions: Other: pharmacological study;   Biological: monoclonal antibody Ch14.18;   Biological: sargramostim;   Other: laboratory biomarker analysis
3 Completed R(+)XK469 in Treating Patients With Advanced Neuroblastoma
Conditions: Disseminated Neuroblastoma;   Localized Unresectable Neuroblastoma;   Recurrent Neuroblastoma;   Regional Neuroblastoma
Intervention: Drug: R(+)XK469
4 Active, not recruiting Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma
Conditions: Disseminated Neuroblastoma;   Localized Resectable Neuroblastoma;   Localized Unresectable Neuroblastoma;   Regional Neuroblastoma;   Stage 4S Neuroblastoma
Interventions: Biological: therapeutic immune globulin;   Other: clinical observation;   Drug: cyclophosphamide;   Drug: prednisone;   Procedure: magnetic resonance imaging;   Other: laboratory biomarker analysis
5 Recruiting Lenalidomide and Monoclonal Antibody With or Without Isotretinoin in Treating Younger Patients With Refractory or Recurrent Neuroblastoma
Conditions: Disseminated Neuroblastoma;   Localized Unresectable Neuroblastoma;   Recurrent Neuroblastoma;   Regional Neuroblastoma;   Stage 4S Neuroblastoma
Interventions: Drug: lenalidomide;   Biological: monoclonal antibody Ch14.18;   Drug: isotretinoin;   Other: pharmacological study;   Other: laboratory biomarker analysis
6 Recruiting Isotretinoin With or Without Monoclonal Antibody, Interleukin-2, and Sargramostim Following Stem Cell Transplantation in Treating Patients With Neuroblastoma
Conditions: Disseminated Neuroblastoma;   Localized Resectable Neuroblastoma;   Localized Unresectable Neuroblastoma;   Regional Neuroblastoma;   Stage 4S Neuroblastoma
Interventions: Drug: isotretinoin;   Biological: sargramostim;   Biological: monoclonal antibody Ch14.18;   Biological: aldesleukin;   Other: laboratory biomarker analysis;   Procedure: quality-of-life assessment;   Other: pharmacological study
7 Active, not recruiting Monoclonal Antibody Ch14.18, Sargramostim, Aldesleukin, and Isotretinoin After Autologous Stem Cell Transplant in Treating Patients With Neuroblastoma
Conditions: Disseminated Neuroblastoma;   Localized Resectable Neuroblastoma;   Localized Unresectable Neuroblastoma;   Regional Neuroblastoma;   Stage 4S Neuroblastoma
Interventions: Biological: aldesleukin;   Other: diagnostic laboratory biomarker analysis;   Biological: sargramostim;   Biological: monoclonal antibody Ch14.18;   Drug: isotretinoin
8 Suspended Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin
Conditions: Disseminated Neuroblastoma;   Localized Resectable Neuroblastoma;   Localized Unresectable Neuroblastoma;   Regional Neuroblastoma;   Stage 4S Neuroblastoma
Interventions: Drug: doxorubicin hydrochloride;   Drug: irinotecan hydrochloride;   Other: pharmacological study;   Other: questionnaire administration;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: in vitro-treated peripheral blood stem cell transplantation;   Procedure: therapeutic conventional surgery;   Radiation: 3-dimensional conformal radiation therapy;   Radiation: external beam radiation therapy;   Radiation: intensity-modulated radiation therapy;   Drug: cyclophosphamide;   Drug: topotecan hydrochloride;   Drug: cisplatin;   Drug: etoposide phosphate;   Drug: vincristine sulfate;   Radiation: iobenguane I 131;   Drug: busulfan;   Drug: melphalan;   Drug: isotretinoin
9 Completed Monoclonal Antibody Therapy With Sargramostim and Interleukin-2 in Treating Children With Neuroblastoma
Conditions: Disseminated Neuroblastoma;   Recurrent Neuroblastoma;   Regional Neuroblastoma
Interventions: Biological: monoclonal antibody Ch14.18;   Drug: isotretinoin;   Biological: aldesleukin;   Biological: sargramostim
10 Completed A Trial Using Molecular-Guided Therapy in Patients With Refractory or Recurrent Neuroblastoma
Conditions: Refractory Neuroblastoma;   Relapsed Neuroblastoma
Intervention:
11 Completed ABT-751 in Treating Children With Neuroblastoma That Has Relapsed or Not Responded to Previous Treatment
Conditions: Disseminated Neuroblastoma;   Recurrent Neuroblastoma
Interventions: Drug: ABT-751;   Other: pharmacological study;   Procedure: quality-of-life assessment
12 Terminated Pyrazoloacridine and Stem Cell or Bone Marrow Transplantation in Treating Young Patients With High-Risk Neuroblastoma
Conditions: Disseminated Neuroblastoma;   Recurrent Neuroblastoma
Interventions: Drug: pyrazoloacridine;   Biological: filgrastim;   Procedure: autologous bone marrow transplantation;   Procedure: peripheral blood stem cell transplantation;   Other: laboratory biomarker analysis;   Other: pharmacological study
13 Withdrawn High-Dose Iodine I 131 Metaiodobenzylguanidine, Topotecan, and Peripheral Stem Cell Transplant in Treating Young Patients With Relapsed Stage 4 Neuroblastoma or Primary Resistant High-Risk Neuroblastoma
Condition: Neuroblastoma
Interventions: Drug: iodine I 131 metaiodobenzylguanidine;   Drug: topotecan hydrochloride;   Procedure: chemotherapy;   Procedure: peripheral blood stem cell transplantation;   Procedure: radioisotope therapy;   Procedure: radionuclide imaging;   Procedure: radiosensitization;   Procedure: total-body irradiation
14 Active, not recruiting Allogeneic Neuroblastoma Cells for Relapsed/ Refractory Neuroblastoma, CYCHEALL
Condition: Neuroblastoma
Intervention: Biological: Injection of allogeneic neuroblastoma cells
15 Terminated
Has Results 		Neuroblastoma Protocol 2008: Therapy for Children With Advanced Stage High Risk Neuroblastoma
Condition: Neuroblastoma
Interventions: Drug: Temsirolimus;   Drug: Irinotecan;   Procedure: Surgical Resection of Primary Tumor;   Drug: Cyclophosphamide;   Drug: Doxorubicin;   Drug: Etoposide;   Drug: Cisplatin;   Drug: Topotecan;   Procedure: PBSC;   Radiation: Radiation Therapy;   Drug: 13-cis-retinoic acid
16 Completed Gene Modified Allogeneic Neuroblastoma Cells For Treatment of Relapsed/Refractory Neuroblastoma
Condition: Neuroblastoma
Intervention: Drug: Interleukin-2
17 Unknown † Genetic Biomarkers in Children With Neuroblastoma (Also Known as Neuroblastoma Epidemiology in North America [NENA])
Condition: Neuroblastoma
Interventions: Genetic: DNA analysis;   Genetic: cytogenetic analysis;   Genetic: polymerase chain reaction;   Genetic: polymorphism analysis;   Other: questionnaire administration;   Other: study of socioeconomic and demographic variables
18 Completed Using Gene Modified Neuroblastoma Cells for the Treatment of Relapsed/Refractory Neuroblastoma
Condition: Neuroblastoma
Interventions: Procedure: Skin Biopsy;   Genetic: Gene Modified Neuroblastoma Cells
19 Unknown † Chemotherapy and Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma
Condition: Neuroblastoma
Interventions: Biological: filgrastim;   Drug: carboplatin;   Drug: cisplatin;   Drug: cyclophosphamide;   Drug: dacarbazine;   Drug: doxorubicin hydrochloride;   Drug: etoposide;   Drug: ifosfamide;   Drug: melphalan;   Drug: tretinoin;   Drug: vincristine sulfate;   Drug: vindesine;   Procedure: autologous bone marrow transplantation;   Procedure: conventional surgery;   Procedure: peripheral blood stem cell transplantation;   Radiation: radiation therapy
20 Unknown † Topotecan, Vincristine, and Doxorubicin in Treating Young Patients With Refractory Stage 4 Neuroblastoma
Condition: Neuroblastoma
Interventions: Biological: filgrastim;   Drug: doxorubicin hydrochloride;   Drug: topotecan hydrochloride;   Drug: vincristine sulfate
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† Indicates status has not been verified in more than two years