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33 studies found for:    "Multiple system atrophy (MSA) with orthostatic hypotension"

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Rank Status Study
1 Completed Droxidopa in Treating Patients With Neurogenic Hypotension
Conditions: Shy-Drager Syndrome;   Orthostatic Hypotension
Intervention: Drug: droxidopa
2 Recruiting The Autonomic Nervous System and Obesity
Conditions: OBESITY;   HYPERTENSION;   PURE AUTONOMIC FAILURE;   SHY-DRAGER SYNDROME
Interventions: Drug: Trimethaphan;   Drug: Pseudoephedrine
3 Unknown † Fipamezole in Neurogenic Orthostatic Hypotension
Conditions: Symptomatic Neurogenic Orthostatic Hypotension (NOH);   Parkinson's Disease;   Multiple System Atrophy
Interventions: Drug: Placebo;   Drug: Fipamezole
4 Terminated Augmenting Effects of L-DOPS With Carbidopa and Entacapone
Conditions: Parkinson Disease;   Multiple System Atrophy;   Autonomic Nervous System Diseases
Intervention: Drug: L-DOPS
5 Recruiting Droxidopa / Pyridostigmine in Orthostatic Hypotension
Conditions: Orthostatic Hypotension;   Multiple System Atrophy
Interventions: Drug: Droxidopa;   Drug: Pyridostigmine Bromide
6 Enrolling by invitation Botulinum A Toxin in Patients With Parkinson's Disease
Conditions: Parkinson's Disease;   Multiple System Atrophy;   Detrusor Overactivity
Intervention: Drug: Intravesical injection of Botulinum A toxin
7 Recruiting Investigation of the Serotoninergic System in Multiple System Atrophy: a Positron Emission Tomography (PET) Study
Condition: Multiple System Atrophy
Interventions: Radiation: PET (Positron Emission Tomography) Study;   Other: Brain MRI (magnetic resonance imaging);   Drug: Fluoxétine / Placebo
8 Recruiting The Role of Endothelin in the Supine Hypertension of Autonomic Failure
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions: Drug: BQ123;   Drug: Bq123;   Drug: Saline
9 Completed Study of Rifampicin in Multiple System Atrophy
Condition: Multiple System Atrophy
Interventions: Drug: Rifampicin;   Drug: placebo
10 Terminated Neuroprotection and Natural History in Parkinson's Plus Syndromes (NNIPPS)
Conditions: Multiple System Atrophy;   Progressive Supranuclear Palsy
Intervention: Drug: Riluzole
11 Completed Fluoxetine in Multiple System Atrophy Patients
Condition: Multiple System Atrophy
Intervention: Drug: FLUOXETINE
12 Completed Diagnosis and Natural History Study of Patients With Neurological Conditions
Conditions: Alzheimer's Disease;   Dementia;   Movement Disorder;   Multiple System Atrophy;   Parkinson's Disease
Intervention:
13 Recruiting Oligomeric Alpha-synuclein in Multiple System Atrophy
Condition: Multiple System Atrophy (MSA)
Intervention:
14 Completed Assessment of Ambulatory Polygraphy in the Detection of Sleep Apnea in Multiple System Atrophy (SAMSA)
Conditions: Sleep Apnea Syndromes;   Multiple System Atrophy
Interventions: Device: Polysomnography;   Device: ambulatory polygraphy
15 Completed Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH)
Conditions: Neurogenic Orthostatic Hypotension;   Non-Diabetic Autonomic Neuropathy;   Multiple System Atrophy;   Dopamine Beta Hydroxylase Deficiency
Interventions: Drug: Droxidopa;   Drug: Placebo
16 Completed Trial of Autologous Mesenchymal Stem Cells in Patients With Multiple System Atrophy
Condition: Multiple System Atrophy
Interventions: Biological: autologous mesenchymal stem cells;   Biological: normal saline
17 Completed Clinical Trial to Assess Efficacy, Safety, and Tolerability of Rasagiline Mesylate 1 mg in Patients With Multiple System Atrophy of the Parkinsonian Subtype (MSA-P)
Condition: Multiple System Atrophy
Interventions: Drug: rasagiline mesylate;   Other: placebo
18 Recruiting Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension
Conditions: Orthostatic Hypotension;   Pure Autonomic Failure;   Multiple System Atrophy;   Parkinson's Disease
Intervention:
19 Active, not recruiting Treatment of Multiple System Atrophy Using Intravenous Immunoglobulins
Condition: Multiple System Atrophy
Intervention: Drug: intravenous immunoglobulin (IVIg)
20 Recruiting Magnetic Resonance Spectroscopy in Autonomic Failure
Conditions: Pure Autonomic Failure;   Multiple System Atrophy
Intervention: Procedure: Magnetic Resonance Spectroscopy Imaging
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† Indicates status has not been verified in more than two years