42 studies found for:    "Multiple system atrophy (MSA) with orthostatic hypotension"
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Study Details
Participant Details
Identifiers
Dates
Rank Status Study
1 Completed Droxidopa in Treating Patients With Neurogenic Hypotension
Conditions: Shy-Drager Syndrome;   Orthostatic Hypotension
Intervention: Drug: droxidopa
2 Not yet recruiting Water and Sudafed in Autonomic Failure
Conditions: Shy-Drager Syndrome;   Multiple System Atrophy
Interventions: Drug: Pseudoephedrine + 480 ml water;   Drug: Pseudoephedrine + 50 ml water;   Other: Placebo + 480 ml water;   Other: Placebo + 50 ml water
3 Recruiting The Autonomic Nervous System and Obesity
Conditions: OBESITY;   HYPERTENSION;   PURE AUTONOMIC FAILURE;   SHY-DRAGER SYNDROME
Interventions: Drug: Trimethaphan;   Drug: Pseudoephedrine
4 Unknown  Fipamezole in Neurogenic Orthostatic Hypotension
Conditions: Symptomatic Neurogenic Orthostatic Hypotension (NOH);   Parkinson's Disease;   Multiple System Atrophy
Interventions: Drug: Placebo;   Drug: Fipamezole
5 Recruiting PET Imaging Study of Neurochemical and Autonomic Disorders in Multiple System Atrophy (MSA)
Conditions: Multiple System Atrophy - Parkinsonian Subtype (MSA-P);   Multiple System Atrophy - Cerebellar Subtype (MSA-C)
Intervention:
6 Active, not recruiting Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension
Conditions: Orthostatic Hypotension;   Pure Autonomic Failure;   Multiple System Atrophy;   Parkinson's Disease
Intervention:
7 Recruiting Treatment of Parkinson Disease and Multiple System Atrophy Using Intranasal Insulin.
Conditions: Parkinson Disease;   Multiple System Atrophy
Intervention: Drug: Intranasal Insulin
8 Recruiting Biomarkers in Parkinsonian Syndromes
Conditions: Parkinsonian Syndromes;   Parkinson's Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy
Interventions: Other: CSF, blood and urine sampling;   Other: clinical measures of disease severity and progression
9 Not yet recruiting Study Assessing Safety and Therapeutic Activity of AFFITOPE® PD01A and PD03A in Patients With Early MSA
Conditions: Multiple System Atrophy;   Neurodegenerative Diseases
Interventions: Biological: AFFITOPE® PD01A + Adjuvant;   Biological: AFFITOPE® PD03A + Adjuvant;   Biological: Adjuvant without active component
10 Recruiting Contribution of Angiotensin II to Supine Hypertension in Autonomic Failure
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions: Drug: Losartan;   Drug: Captopril;   Drug: Placebo
11 Recruiting Defining Phenotypes of Movement Disorders :Parkinson's Plus Disorders, PD,Essential Tremor, (ET),Cortical Basal Degeneration, (CBD),Multiple Systems Atrophy (MSA), Magnetoencephalography
Conditions: Essential Tremor;   Multiple System Atrophy;   Corticobasal Degeneration;   Supranuclear Palsy, Progressive
Intervention:
12 Recruiting The Role of Endothelin in the Supine Hypertension of Autonomic Failure
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions: Drug: BQ123;   Drug: Bq123;   Drug: Saline
13 Completed Analysis of the Enteric Nervous System Using Colonic Biopsies
Conditions: Parkinson's Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy
Intervention: Procedure: colonoscopy or rectosigmoidoscopy
14 Unknown  Diagnostic and Prognostic Biomarkers in Parkinson Disease
Conditions: Parkinson Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy
Intervention:
15 Completed Fluoxetine in Multiple System Atrophy Patients
Condition: Multiple System Atrophy
Intervention: Drug: FLUOXETINE
16 Completed
Has Results
Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH)
Conditions: Neurogenic Orthostatic Hypotension;   Non-Diabetic Autonomic Neuropathy;   Multiple System Atrophy;   Dopamine Beta Hydroxylase Deficiency
Interventions: Drug: Droxidopa;   Drug: Placebo
17 Completed Evaluation of the Subjective and Objective Painful Threshold in Multiple System Atrophy Pain and Multiple System Atrophy
Conditions: Pain Threshold;   Multiple System Atrophy
Interventions: Drug: Levodopa test;   Procedure: determination of objective and subjective pain threshold
18 Completed Increased Gut Permeability to Lipopolysaccharides (LPS) in Parkinson's Disease
Conditions: Parkinson's Disease;   Multiple System Atrophy
Intervention:
19 Completed Treatment of Multiple System Atrophy Using Intravenous Immunoglobulins
Condition: Multiple System Atrophy
Intervention: Drug: intravenous immunoglobulin (IVIg)
20 Completed Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multiple System Atrophy
Conditions: Parkinson's Disease;   Multiple System Atrophy;   Orthostatic Hypotension
Interventions: Drug: Fludrocortisone;   Drug: Domperidone;   Behavioral: Conservative Measures for Orthostatic Hypotension

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Indicates status has not been verified in more than two years