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31 studies found for:    "Lynch syndrome"

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Rank Status Study
21 Completed Phase I-II Multiple-Dose Safety and Efficacy Study of a Selective Inhibitor of Cyclooxygenase - 2 (SC-58635) in Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Patients and Carriers
Conditions: Colorectal Neoplasm;   Hereditary Nonpolyposis
Intervention: Drug: Celecoxib (SC-58635)
22 Completed CHROENDOHNPCC: Early Detection of Pre-cancer Lesions in Adults With Hereditary Nonpolyposis Colorectal Cancer Syndrome
Condition: Colorectal Neoplasms, Hereditary Nonpolyposis
Intervention: Procedure: Colonoscopy with chromoscopy
23 Unknown † Collecting Information From Patients and Family Members With Hereditary Colorectal Cancer Syndromes or Who Are at High Risk of Developing Colorectal Cancer
Conditions: Colorectal Cancer;   Hereditary Nonpolyposis Colorectal Cancer;   Precancerous Condition
Interventions: Other: study of socioeconomic and demographic variables;   Procedure: evaluation of cancer risk factors;   Procedure: study of high risk factors
24 Completed Educational CD-ROM Compared With Standard Informed Consent for Patients With Colorectal Cancer or a Family History of Colorectal Cancer
Conditions: Colorectal Cancer;   Hereditary Non-polyposis Colon Cancer
Interventions: Genetic: microsatellite instability analysis;   Genetic: mutation analysis;   Genetic: polymerase chain reaction;   Other: counseling intervention;   Other: educational intervention;   Other: immunohistochemistry staining method;   Other: laboratory biomarker analysis
25 Unknown † Biomarkers in Samples From Patients With Endometrial Cancer
Conditions: Endometrial Cancer;   Hereditary Non-polyposis Colon Cancer
Interventions: Genetic: DNA analysis;   Genetic: DNA methylation analysis;   Genetic: gene expression analysis;   Genetic: molecular genetic technique;   Genetic: mutation analysis;   Genetic: polymorphism analysis;   Genetic: reverse transcriptase-polymerase chain reaction;   Genetic: western blotting;   Other: immunohistochemistry staining method;   Other: laboratory biomarker analysis
26 Completed Hormone Therapy in Preventing Endometrial Cancer in Patients With a Genetic Risk For Hereditary Nonpolyposis Colon Cancer
Condition: Endometrial Cancer
Interventions: Drug: medroxyprogesterone;   Drug: ethinyl estradiol;   Drug: norgestrel;   Other: laboratory biomarker analysis
27 Unknown † Study of the Results of Education and Counseling for Persons Undergoing Genetic Testing for Hereditary Nonpolyposis Colon Cancer
Condition: Colorectal Cancer
Interventions: Genetic: loss of heterozygosity analysis;   Genetic: microsatellite instability analysis;   Genetic: mutation analysis;   Other: counseling intervention
28 Active, not recruiting Combined Colon and Endometrial Cancer Screening in Women With HNPCC
Condition: Colon Cancer
Intervention: Behavioral: Interview
29 Recruiting A Social Media Approach to Improve Genetic Risk Communication Phase I
Condition: Hereditary Diseases
Interventions: Behavioral: Audiotaped Focus Group;   Behavioral: Demographic Questionnaire;   Behavioral: Audiotaped Interview;   Behavioral: WAMMI Inventory
30 Recruiting Ileal Pouch-Anal Anastomosis Registry
Condition: Ileal Pouch-Anal Anastomosis
Intervention:
31 Unknown † Establishing Effective Screening Methods for Diagnosing Hereditary Nonpolypoisis Colorectal Cancer
Condition: Colonic Neoplasms
Intervention:
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† Indicates status has not been verified in more than two years