113 studies found for:    "Lipodystrophy"
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Rank Status Study
1 Active, not recruiting Trial of Leptin Replacement Therapy in Patients With Lipodystrophy
Conditions: Hypoleptinemia;   Generalized Lipodystrophy;   Partial Lipodystrophy;   Insulin Resistance
Interventions: Drug: Leptin;   Drug: Placebo
2 Recruiting Therapeutic Approaches to HAART-Induced Lipodystrophy
Conditions: HIV Infections;   Lipodystrophy
Intervention: Drug: Metreleptin  (Leptin)
3 Active, not recruiting Leptin to Treat Lipodystrophy
Condition: Lipodystrophy
Intervention: Drug: Metreleptin
4 Completed Corticosteroid-induced Lipodystrophy and Adipokines
Condition: Lipodystrophy
Intervention: Other: Samples and procedures
5 Recruiting Identification of a New Gene Involved in Hereditary Lipodystrophy
Condition: Lipodystrophy
Interventions: Genetic: Amplification by PCR and direct sequencing on the entire coding sequence and intron-exons boundaries of the candidate gene;   Biological: Perform blood cells and fibroblasts biochemical and immuno-labeled investigations
6 Recruiting Short-term Effects of Leptin in People With Lipodystrophy
Condition: Lipodystrophy
Intervention: Biological: Metreleptin
7 Unknown  Autologous Adipose-Derived Stem Cell Transplantation in Patients With Lipodystrophy
Condition: Lipodystrophy
Intervention: Procedure: autologous transplantation of liposuction material enriched with adipose-derived stem cells
8 Active, not recruiting An Open-Label Treatment Protocol to Provide Metreleptin for the Treatment of Diabetes Mellitus and/or Hypertriglyceridemia Associated With Lipodystrophy
Condition: Lipodystrophy
Intervention: Drug: metreleptin
9 Recruiting Clinical Protocol to Investigate the Efficacy of Recombinant Human Leptin (Metreleptin) in Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) Associated With Lipodystrophy
Conditions: Fatty Liver Disease, Nonalcoholic;   Nonalcoholic Steatohepatitis;   Lipodystrophy
Intervention: Drug: Metreleptin
10 Completed Strategies of Interruption/Reinitiation of Antiretroviral Therapy in HIV-Infected Patients With Lipodystrophy
Condition: HIV-Associated Lipodystrophy Syndrome
Interventions: Drug: Standard continuous antiretroviral therapy;   Drug: CD-4 guided therapy interruption;   Drug: Viral load driven treatment interruption
11 Terminated Facial Lipoatrophy Trial: Immediate Versus Deferred Injections of Poly-L-Lactic Acid for HIV Facial Lipoatrophy
Conditions: HIV-Associated Lipodystrophy;   HIV Infections
Intervention: Device: poly-L-lactic acid
12 Withdrawn Clinical Trial to Determine the Efficacy of Sculptra™ Dermal Filler for the Correction of Contour Deformities Caused by Lipoatrophy
Conditions: Lipodystrophy;   Emaciation
Intervention: Device: Sculptra Injection
13 Terminated Study Evaluating the Impact on Fat Distribution of Nucleoside Reverse Transcriptase Inhibitor (NRTI)-Sparing Regimens in Antiretroviral Experienced Patients With Lipoatrophy
Conditions: HIV Infections;   HIV Lipodystrophy Syndrome
Interventions: Drug: non-nucleoside reverse transcriptase inhibitors;   Drug: nucleoside reverse transcriptase inhibitors;   Drug: protease inhibitors
14 Unknown  Randomized, Placebo-Controlled Study of Leptin for the Treatment of HIV Lipodystrophy and Metabolic Syndrome
Condition: HAART-induced Lipodystrophy and Metabolic Syndrome
Intervention: Drug: r-metHuLeptin
15 Terminated Evaluation of the Occurrence of Lipoatrophy in HIV-1 Infected Naive Patients
Conditions: HIV Infections;   HIV-Associated Lipodystrophy Syndrome
Interventions: Drug: non-nucleoside reverse transcriptase inhibitors;   Drug: nucleoside reverse transcriptase inhibitors;   Drug: protease inhibitor
16 Terminated Effect of Pioglitazone on HIV-1 Related Lipoatrophy: a Randomized, Double Blind, Placebo-Controlled Trial in 130 Patients
Conditions: HIV-Associated Lipodystrophy Syndrome;   HIV Infections
Intervention: Drug: Pioglitazone
17 Completed Safety and Efficacy of Intradermal Injections of Newfill Versus Eutrophill in the Treatment of Facial Lipoatrophy in HIV-infected Patients ANRS 132 SMILE
Condition: HIV-Associated Lipodystrophy Syndrome
Interventions: Device: Newfill;   Device: Eutrophill
18 Completed Leptin for Abnormal Lipid Kinetics in HIV Lipodystrophy Syndrome
Condition: HIV Lipodystrophy
Interventions: Drug: Human recombinant leptin ("metreleptin");   Drug: Placebo
19 Completed
Has Results
Study of Reyataz in HIV-infected Patients With Lipodystrophy Syndrome
Condition: HIV-Associated Lipodystrophy Syndrome
Interventions: Drug: Atazanavir (ATV) + ritonavir (RTV), continuation of backbone 2 nucleoside reverse transcriptase inhibitor (NRTIs);   Drug: continuation of current HAART (boosted protease inhibitor [PI] combination + 2 NRTIs)
20 Completed Leptin to Treat Lipodystrophy
Condition: Lipodystrophy
Intervention: Drug: hu Leptin (A-100)

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