874 studies found for:    "Glioblastoma"
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Rank Status Study
1 Recruiting A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma
Conditions: Glioblastoma;   Small Cell Glioblastoma;   Giant Cell Glioblastoma;   Gliosarcoma;   Glioblastoma With Oligodendroglial Component;   Recurrent Glioblastoma;   Relapsed Glioblastoma
Interventions: Drug: Bevacizumab;   Drug: Rindopepimut (CDX-110) with GM-CSF;   Drug: KLH
2 Recruiting Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma
Conditions: Glioblastoma;   Small Cell Glioblastoma;   Giant Cell Glioblastoma;   Gliosarcoma;   Glioblastoma With Oligodendroglial Component
Interventions: Drug: Rindopepimut (CDX-110) with GM-CSF;   Drug: Temozolomide;   Drug: KLH
3 Recruiting Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma
Conditions: Glioblastoma;   Glioblastoma Multiforme;   Glioma;   Astrocytoma;   Brain Tumor
Interventions: Biological: Dendritic cell vaccination, in addition to standard temozolomide chemotherapy and involved field radiation therapy;   Biological: Dendritic cell vaccination, with optional bevacizumab treatment for patients previously treated with bevacizumab
4 Recruiting Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma
Conditions: Giant Cell Glioblastoma;   Glioblastoma;   Gliosarcoma
Interventions: Biological: bevacizumab;   Drug: temozolomide;   Other: laboratory biomarker analysis;   Other: immunohistochemistry staining method;   Genetic: microarray analysis;   Genetic: DNA methylation analysis
5 Recruiting NovoTTF-100A With Bevacizumab (Avastin) in Patients With Recurrent Glioblastoma
Conditions: Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Biological: Bevacizumab;   Device: NovoTTF-l00A;   Other: Quality of Life Assessment
6 Active, not recruiting Safety Study of XL184 (Cabozantinib) in Combination With Temozolomide and Radiation Therapy in the Initial Treatment of Adults With Glioblastoma
Conditions: Glioblastoma;   Giant Cell Glioblastoma;   Gliosarcoma
Interventions: Drug: XL184;   Drug: temozolomide;   Radiation: Radiation Therapy
7 Not yet recruiting A Pilot Trial Testing the Feasibility of Molecular Profiling in Recurrent/Progressive Glioblastoma
Conditions: Recurrent Glioblastoma;   Progressive Glioblastoma
Intervention:
8 Recruiting Efficacy, Safety and CNS Exposure of G-202 in Patients With Recurrent or Progressive Glioblastoma
Conditions: Recurrent Glioblastoma;   Progressive Glioblastoma
Intervention: Drug: G-202
9 Not yet recruiting Safety and Efficacy Study of Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme
Conditions: Adult Brain Glioblastoma;   Glioblastoma Multiforme
Interventions: Biological: SL-701; Imiquimod Cream 5%; Leukine 150 micrograms;   Drug: Imiquimod Cream 5%;   Drug: Leukine 150 micrograms
10 Recruiting WEE1 Inhibitor MK-1775, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme
Conditions: Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Drug: WEE1 inhibitor MK-1775;   Radiation: radiation therapy;   Drug: temozolomide;   Other: pharmacological study;   Other: laboratory biomarker analysis
11 Recruiting Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer
Conditions: Glioblastoma Multiforme;   Glioblastoma;   GBM;   Grade IV Astrocytoma;   Glioma;   Brain Cancer;   Brain Tumor
Intervention: Drug: Dendritic cell immunotherapy
12 Completed Pazopanib in Treating Patients With Recurrent Glioblastoma
Conditions: Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Drug: pazopanib hydrochloride;   Other: laboratory biomarker analysis
13 Recruiting PF-00299804 in Adult Patients With Relapsed/Recurrent Glioblastoma
Conditions: Glioblastoma;   GBM;   Glioblastoma Multiforme
Intervention: Drug: PF-00299804
14 Active, not recruiting Sorafenib and Temsirolimus in Treating Patients With Recurrent Glioblastoma
Conditions: Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Drug: sorafenib tosylate;   Drug: temsirolimus;   Procedure: conventional surgery
15 Active, not recruiting Cediranib Maleate and Cilengitide in Treating Patients With Progressive or Recurrent Glioblastoma
Conditions: Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Drug: cediranib maleate;   Drug: cilengitide;   Other: laboratory biomarker analysis
16 Completed Tandutinib in Treating Patients With Recurrent or Progressive Glioblastoma
Conditions: Adult Brain Tumor;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Procedure: conventional surgery;   Drug: tandutinib;   Other: pharmacological study;   Other: biopsy
17 Enrolling by invitation Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma
Conditions: Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma
Interventions: Drug: temozolomide;   Biological: malignant glioma tumor lysate-pulsed autologous dendritic cell vaccine;   Other: laboratory biomarker analysis
18 Recruiting Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma
Conditions: Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Biological: bevacizumab;   Radiation: intensity-modulated radiation therapy;   Radiation: 3-dimensional conformal radiation therapy;   Radiation: proton beam radiation therapy
19 Recruiting A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme
Conditions: Glioblastoma;   GBM;   Glioblastoma Multiforme
Interventions: Drug: Ascorbate;   Drug: Temozolomide;   Radiation: Radiation therapy
20 Active, not recruiting Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Recurrent or Progressive Glioblastoma
Conditions: Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Drug: gamma-secretase/Notch signalling pathway inhibitor RO4929097;   Procedure: therapeutic conventional surgery;   Other: pharmacological study;   Other: laboratory biomarker analysis

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Indicates status has not been verified in more than two years