61 studies found for:    "Fanconi anemia"
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Rank Status Study
1 Active, not recruiting Tissue Sample Collection From Patients With Fanconi Anemia
Conditions: Fanconi Anemia;   Unspecified Adult Solid Tumor, Protocol Specific;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Other: biologic sample preservation procedure;   Procedure: biopsy
2 Completed Oxandrolone for the Treatment of Bone Marrow Aplasia in Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Drug: Oxandrolone
3 Unknown  Research Study in Healthy Volunteers or Patients With Fanconi Anemia, Myeloproliferative Disorders, or Myeloma
Conditions: Chronic Myeloproliferative Disorders;   Fanconi Anemia;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic/Myeloproliferative Neoplasms
Interventions: Genetic: microarray analysis;   Genetic: polyacrylamide gel electrophoresis;   Genetic: polymerase chain reaction;   Genetic: protein expression analysis;   Genetic: reverse transcriptase-polymerase chain reaction;   Genetic: western blotting;   Other: chromatography;   Other: high performance liquid chromatography;   Other: immunoenzyme technique
4 Recruiting Cyclophosphamide, Fludarabine, and Antithymocyte Globulin Followed By Donor Stem Cell Transplant in Treating Patients With Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Biological: anti-thymocyte globulin;   Drug: cyclophosphamide;   Drug: fludarabine phosphate;   Procedure: hematopoietic stem cell transplantation;   Drug: methylprednisolone;   Drug: filgrastim;   Drug: cyclosporine;   Drug: Mycophenolate Mofetil
5 Recruiting Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Biological: anti-thymocyte globulin;   Biological: filgrastim;   Drug: busulfan;   Drug: cyclophosphamide;   Drug: fludarabine phosphate;   Drug: methylprednisolone;   Biological: Hematopoietic stem cell transplantation
6 Terminated
Has Results
Antibody Conditioning Regimen For Allogeneic Donor Stem Cell Transplantation Of Patients With Fanconi Anemia
Conditions: Fanconi Anemia;   Severe Aplastic Anemia
Interventions: Biological: CAMPATH-1H;   Biological: Anti-CD45;   Drug: Fludarabine;   Procedure: Stem cell infusion
7 Completed Pilot Study of Etanercept (Enbrel) in Children With Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Drug: Etanercept
8 Recruiting Hematopoietic Stem Cell Transplant for Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Device: CliniMACs device
9 Recruiting Quercetin in Children With Fanconi Anemia; a Pilot Study
Condition: Fanconi Anemia
Intervention: Drug: Quercetin (dietary supplement)
10 Terminated Gene Function in Bone Marrow Cells From Patients With Fanconi Anemia and From Healthy Participants
Condition: Fanconi Anemia
Interventions: Genetic: microarray analysis;   Procedure: biopsy
11 Available Use Massive Parallel Sequencing and Exome Capture Technology to Sequence the Exome of Fanconi Anemia Children and Their Patents
Conditions: Fanconi Anemia;   Autosomal or Sex Linked Recessive Genetic Disease;   Bone Marrow Hematopoiesis Failure, Multiple Congenital Abnormalities, and Susceptibility to Neoplastic Diseases.;   Hematopoiesis Maintainance.
Interventions: Genetic: human whole exome;   Genetic: whole genomic
12 Completed Cyclophosphamide in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Fanconi's Anemia
Condition: Fanconi Anemia
Interventions: Drug: cyclophosphamide;   Drug: cyclosporine;   Drug: methotrexate;   Procedure: allogeneic bone marrow transplantation;   Procedure: nonmyeloablative allogeneic hematopoietic stem cell transplantation
13 Terminated
Has Results
Stem Cell Transplantation for Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Procedure: Hematopoietic Stem Cell Transplant;   Procedure: Thymic Shielding During Radiation;   Procedure: Total Body Irradiation;   Drug: Cyclophosphamide, Fludarabine
14 Recruiting Gene Therapy for Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Procedure: harvest procedure;   Biological: genetically engineered lymphocyte therapy;   Other: laboratory biomarker analysis
15 Completed Bone Marrow Cell Gene Transfer in Individuals With Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Genetic: Retrovirus Construct
16 Recruiting TBI Dose De-escalation for Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Drug: Cyclophosphamide;   Drug: Fludarabine;   Procedure: Total Body Irradiation;   Procedure: Bone Marrow Transplantation;   Drug: Mycophenolate Mofetil;   Drug: Sirolimus
17 Completed Blood Cell Collection for Future Use in Individuals With Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Procedure: PBSC Collection;   Procedure: Bone Marrow Harvest;   Device: CliniMacs Cell Selection System
18 Active, not recruiting Low-Dose Total-Body Irradiation and Fludarabine Phosphate Followed by Unrelated Donor Stem Cell Transplant in Treating Patients With Fanconi Anemia
Conditions: Adult Acute Myeloid Leukemia in Remission;   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Childhood Acute Myeloid Leukemia in Remission;   Childhood Myelodysplastic Syndromes;   Fanconi Anemia;   Previously Treated Myelodysplastic Syndromes
Interventions: Drug: fludarabine phosphate;   Drug: cyclosporine;   Radiation: total-body irradiation;   Procedure: allogeneic bone marrow transplantation;   Procedure: allogeneic hematopoietic stem cell transplantation;   Procedure: peripheral blood stem cell transplantation;   Drug: mycophenolate mofetil
19 Recruiting Identification of de Novo Fanconi Anemia in Younger Patients With Newly Diagnosed Acute Myeloid Leukemia
Conditions: Childhood Acute Erythroleukemia (M6);   Childhood Acute Megakaryocytic Leukemia (M7);   Childhood Acute Minimally Differentiated Myeloid Leukemia (M0);   Childhood Acute Monoblastic Leukemia (M5a);   Childhood Acute Monocytic Leukemia (M5b);   Childhood Acute Myeloblastic Leukemia With Maturation (M2);   Childhood Acute Myeloblastic Leukemia Without Maturation (M1);   Childhood Acute Myelomonocytic Leukemia (M4);   Childhood Myelodysplastic Syndromes;   Chronic Myelomonocytic Leukemia;   de Novo Myelodysplastic Syndromes;   Fanconi Anemia;   Refractory Anemia;   Refractory Anemia With Excess Blasts;   Refractory Anemia With Excess Blasts in Transformation;   Refractory Anemia With Ringed Sideroblasts;   Secondary Myelodysplastic Syndromes;   Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies
Intervention: Other: laboratory biomarker analysis
20 Active, not recruiting Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant, Mycophenolate Mofetil, and Cyclosporine in Treating Patients With Fanconi Anemia
Conditions: Adult Acute Myeloid Leukemia in Remission;   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Childhood Acute Myeloid Leukemia in Remission;   Childhood Myelodysplastic Syndromes;   de Novo Myelodysplastic Syndromes;   Fanconi Anemia;   Previously Treated Myelodysplastic Syndromes
Interventions: Drug: fludarabine phosphate;   Drug: cyclophosphamide;   Radiation: total-body irradiation;   Procedure: allogeneic bone marrow transplantation;   Drug: mycophenolate mofetil;   Drug: cyclosporine;   Procedure: nonmyeloablative allogeneic hematopoietic stem cell transplantation

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Indicates status has not been verified in more than two years