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166 studies found for:    "Ewings family of tumors"

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1 Not yet recruiting Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed By Stem Cell Rescue in Treating Patients With Poor-Risk Ewing Sarcoma
Conditions: Adult Supratentorial Primitive Neuroectodermal Tumor (PNET);   Ewing Sarcoma of Bone;   Extraosseous Ewing Sarcoma;   Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor;   Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor
Interventions: Drug: etoposide;   Drug: ifosfamide;   Radiation: intensity-modulated radiation therapy;   Drug: topotecan hydrochloride;   Drug: busulfan;   Drug: melphalan;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: peripheral blood stem cell transplantation;   Procedure: autologous bone marrow transplantation
2 Recruiting 18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcoma
Conditions: Adult Supratentorial Primitive Neuroectodermal Tumor (PNET);   Ewing Sarcoma of Bone;   Extraosseous Ewing Sarcoma;   Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor
Interventions: Other: fluorine F 18 fluorothymidine;   Radiation: fludeoxyglucose F 18;   Procedure: positron emission tomography;   Procedure: diffusion-weighted magnetic resonance imaging;   Other: laboratory biomarker analysis
3 Recruiting Dasatinib and Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumors or Other Sarcomas That Cannot be Removed by Surgery or Are Metastatic
Conditions: Chondrosarcoma;   Clear Cell Sarcoma of the Kidney;   Endometrial Stromal Sarcoma;   Ewing Sarcoma of Bone;   Extraosseous Ewing Sarcoma;   Gastrointestinal Stromal Tumor;   Mast Cell Sarcoma;   Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Metastatic Osteosarcoma;   Ovarian Sarcoma;   Recurrent Adult Soft Tissue Sarcoma;   Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Recurrent Osteosarcoma;   Recurrent Uterine Sarcoma;   Stage III Adult Soft Tissue Sarcoma;   Stage III Uterine Sarcoma;   Stage IV Adult Soft Tissue Sarcoma;   Stage IV Uterine Sarcoma
Interventions: Drug: dasatinib;   Biological: ipilimumab;   Other: laboratory biomarker analysis;   Other: pharmacological study
4 Completed Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of Chemotherapy
Conditions: Ewing's Sarcoma;   Primitive Neuroectodermal Tumor (PNET);   Askin's Tumor of the Chest Wall;   Extraosseous Ewing's Sarcoma (EOE)
Intervention: Drug: Zalypsis
5 Active, not recruiting Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor
Conditions: Solid Tumor;   Adult Central Nervous System Germ Cell Tumor;   Adult Rhabdomyosarcoma;   Childhood Central Nervous System Germ Cell Tumor;   Childhood Soft Tissue Sarcoma;   Ewing Sarcoma;   Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Ovarian Mixed Germ Cell Tumor;   Previously Untreated Childhood Rhabdomyosarcoma;   Recurrent Adult Brain Tumor;   Recurrent Adult Soft Tissue Sarcoma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Malignant Germ Cell Tumor;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Pineoblastoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma;   Recurrent Childhood Visual Pathway Glioma;   Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Recurrent Extragonadal Germ Cell Tumor;   Recurrent Extragonadal Non-seminomatous Germ Cell Tumor;   Recurrent Malignant Testicular Germ Cell Tumor;   Recurrent Neuroblastoma;   Recurrent Ovarian Germ Cell Tumor;   Recurrent Wilms Tumor and Other Childhood Kidney Tumors;   Unspecified Adult Solid Tumor, Protocol Specific;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: busulfan;   Drug: melphalan;   Drug: topotecan hydrochloride;   Other: laboratory biomarker analysis;   Biological: filgrastim;   Procedure: autologous hematopoietic stem cell transplantation;   Other: pharmacological study;   Procedure: autologous bone marrow transplantation
6 Recruiting Study in Localized and Disseminated Ewing Sarcoma
Condition: Ewing's Sarcoma
Interventions: Drug: Zoledronic acid;   Drug: Busulfan;   Drug: Treosulfan
7 Recruiting PK/PD of XM22 in Children With Ewing Family of Tumors or Rhabdomyosarcoma
Condition: Ewing Family of Tumors, Rhabdomyosarcoma
Intervention: Drug: Lipegfilgrastim
8 Completed Aerosol L9-NC and Temozolomide in Ewing's Sarcoma
Condition: Ewing's Sarcoma
Interventions: Drug: Temozolomide;   Drug: L9-NC
9 Active, not recruiting Vincristine, Doxorubicin, Cyclophosphamide and Dexrazoxane (VACdxr) in High Risk Ewing's Sarcoma Patients
Condition: Ewing's Sarcoma
Interventions: Drug: Vincristine;   Drug: Doxorubicin;   Drug: Cyclophosphamide;   Drug: Dexrazoxane;   Biological: ImmTher
10 Completed Prognostic Value of a Positive RT-PCR Test in Patients With Ewing Sarcoma
Condition: Non-Metastatic Ewings Sarcoma
Intervention:
11 Recruiting Study of Intensive Chemotherapy, Surgery and Radiotherapy to Treat Ewing's Sarcoma in Children and Young Adults
Condition: Ewing's Sarcoma
Interventions: Drug: Chemotherapy;   Procedure: Surgery;   Radiation: Radiotherapy
12 Terminated Study on VCD/IE in the Patients With Ewing's Sarcoma Family of Tumors (ESFT)
Condition: Ewing's Sarcoma
Intervention: Drug: VCR, CTX, ADM; IFO, VP-16
13 Not yet recruiting Phase I Study of Olaprib and Temozolomide for Ewings Sarcoma
Condition: Ewing Sarcoma
Interventions: Drug: Olaparib;   Drug: Temozolomide
14 Recruiting Cyclophosphamide, Doxorubicin, Vincristine w/ Irinotecan and Temozolomide in Ewings Sarcoma
Conditions: Bone Cancer;   Ewing's Sarcoma
Interventions: Drug: Irinotecan;   Drug: Vincristine;   Drug: Temozolomide;   Drug: Doxorubicin;   Drug: Cytoxan;   Drug: Pegfilgrastim;   Drug: Mesna
15 Recruiting Mithramycin for Children and Adults With Solid Tumors or Ewing Sarcoma
Conditions: Ewing Sarcoma;   Sarcoma
Intervention: Drug: Mithramycin
16 Active, not recruiting Olaparib in Adults With Recurrent/Metastatic Ewing's Sarcoma
Condition: Ewing's Sarcoma
Intervention: Drug: Olaparib
17 Recruiting Osteosarcoma and Ewing Sarcoma Treatment Response Assessment With Functional MRI Imaging in Children and Young Adults
Conditions: Ewing Sarcoma;   Osteosarcoma
Intervention: Other: MRI
18 Recruiting Post-operative Radiotherapy in Poor Responders Ewing's Sarcoma Patients
Condition: Ewing's Sarcoma
Intervention: Radiation: External Beam Radiotherapy
19 Completed New Therapeutic Strategies for Patients With Ewing's Sarcoma Family of Tumors, High Risk Rhabdomyosarcoma, and Neuroblastoma
Conditions: Ewing's Sarcoma;   Neuroblastoma;   Rhabdomyosarcoma
Interventions: Drug: ADR-529;   Drug: Topotecan;   Drug: G-CSF
20 Active, not recruiting A Phase 2 Study of AMG 479 in Relapsed or Refractory Ewing's Family Tumor and Desmoplastic Small Round Cell Tumors
Conditions: Askin's Tumors;   Desmoplastic Small Round Cell Tumors;   Estraosseous Ewing's Tumor;   Ewing's Family Tumor;   Ewing's Sarcoma;   Primitive Neuroectodermal Tumors (PNETs);   Sarcoma
Intervention: Drug: AMG 479
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† Indicates status has not been verified in more than two years