211 studies found for:    "Diffuse scleroderma"
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Rank Status Study
21 Completed Recombinant Human Relaxin in the Treatment of Diffuse Scleroderma
Condition: Systemic Sclerosis
Intervention: Drug: Relaxin
22 Completed Effectiveness and Safety of Lidocaine for Scleroderma
Condition: Scleroderma
Interventions: Drug: Lidocaine 2% without vessel constrictor;   Other: Placebo - physiological solution 0,9%
23 Unknown  Study of Ambrisentan With Antifibrotic Agent Combination Therapy in Diffuse Systemic Sclerosis
Conditions: Systemic Sclerosis;   Scleroderma
Intervention: Drug: Ambrisentan with an anti-fibrotic agent to assess benefit on skin.
24 Recruiting Scleroderma Lung: Role of Gastroesophageal Reflux, Microaspiration and Cough
Condition: Scleroderma Lung
Intervention:
25 Active, not recruiting A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic Sclerosis
Conditions: Pulmonary Arterial Hypertension;   Systemic Sclerosis;   Scleroderma Spectrum of Diseases;   Connective Tissue Disease;   Pulmonary Hypertension
Interventions: Drug: Tadalafil monotherapy;   Drug: Ambrisentan monotherapy;   Drug: tadalafil and ambrisentan
26 Completed Safety, Tolerability, and Pharmacokinetics of CAT-192 (Human Anti-TGF-Beta1 Monoclonal Antibody) in Patients With Early Stage Diffuse Systemic Sclerosis
Conditions: Systemic Sclerosis;   Scleroderma
Intervention: Drug: Human Anti-Transforming Growth Factor Beta-1 Monoclonal Antibody
27 Recruiting Rituximab in Systemic Sclerosis
Condition: Systemic Sclerosis
Interventions: Drug: Rituximab;   Drug: Placebo (NaCl)
28 Completed Premature Coronary Atherosclerosis in Scleroderma
Condition: Scleroderma
Intervention:
29 Completed Finger Hardness Measure in Scleroderma
Condition: Scleroderma
Intervention:
30 Completed Oral Type I Collagen for Relieving Scleroderma
Conditions: Scleroderma;   Connective Tissue Diseases
Interventions: Drug: Oral bovine type I collagen;   Drug: Placebo
31 Completed Morbidity and Mortality Follow Up for the Scleroderma Lung Study
Condition: Scleroderma
Intervention: Other: Followup survey
32 Terminated
Has Results
Placebo Controlled Trial of Bosentan in Scleroderma Patients
Conditions: Systemic Scleroderma;   Pulmonary Hypertension
Interventions: Drug: Bosentan;   Drug: Placebo
33 Recruiting Calcinosis in a Single-Center Scleroderma Population
Conditions: Scleroderma;   Calcinosis
Intervention:
34 Completed Sleep Disturbances and Pulmonary Artery/Aorta Diameter in Scleroderma Patient
Conditions: Scleroderma;   Pulmonary Hypertension
Intervention:
35 Unknown  AIMSPRO in Established Diffuse Cutaneous Systemic Sclerosis
Condition: Systemic Sclerosis
Interventions: Drug: Hyperimmune caprine serum;   Drug: Albumin
36 Active, not recruiting Comparison of Therapeutic Regimens for Scleroderma Interstitial Lung Disease (The Scleroderma Lung Study II)
Conditions: Scleroderma;   Interstitial Lung Disease
Interventions: Drug: Mycophenolate mofetil;   Drug: Cyclophosphamide;   Drug: Placebo
37 Not yet recruiting Efficacy of Botulinum Toxin In Scleroderma-Associated Raynaud's Syndrome
Conditions: Scleroderma;   Raynaud's Syndrome
Interventions: Drug: Onabotulinumtoxin A;   Drug: sterile saline solution
38 Recruiting Effect of Bosentan in Scleroderma Renal Crisis
Condition: Scleroderma Renal Crisis
Intervention: Drug: Bosentan
39 Completed A Randomized Control Trial to Assess the Efficacy of Tadalafil in Raynaud's Phenomenon in Scleroderma
Conditions: Raynaud's Phenomenon;   Digital Ulcers;   Scleroderma
Interventions: Drug: Tadalafil;   Drug: Placebo
40 Terminated Thalidomide for Decreasing Collagen Biosynthesis in People With Progressive Systemic Sclerosis
Condition: Scleroderma, Systemic
Interventions: Drug: Thalidomide;   Drug: Placebo thalidomide

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Indicates status has not been verified in more than two years