203 studies found for:    "Diffuse scleroderma"
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Rank Status Study
21 Unknown  Study of Ambrisentan With Antifibrotic Agent Combination Therapy in Diffuse Systemic Sclerosis
Conditions: Systemic Sclerosis;   Scleroderma
Intervention: Drug: Ambrisentan with an anti-fibrotic agent to assess benefit on skin.
22 Completed Safety, Tolerability, and Pharmacokinetics of CAT-192 (Human Anti-TGF-Beta1 Monoclonal Antibody) in Patients With Early Stage Diffuse Systemic Sclerosis
Conditions: Systemic Sclerosis;   Scleroderma
Intervention: Drug: Human Anti-Transforming Growth Factor Beta-1 Monoclonal Antibody
23 Active, not recruiting A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic Sclerosis
Conditions: Pulmonary Arterial Hypertension;   Systemic Sclerosis;   Scleroderma Spectrum of Diseases;   Connective Tissue Disease;   Pulmonary Hypertension
Interventions: Drug: Tadalafil monotherapy;   Drug: Ambrisentan monotherapy;   Drug: tadalafil and ambrisentan
24 Active, not recruiting Comparison of Therapeutic Regimens for Scleroderma Interstitial Lung Disease (The Scleroderma Lung Study II)
Conditions: Scleroderma;   Interstitial Lung Disease
Interventions: Drug: Mycophenolate mofetil;   Drug: Cyclophosphamide;   Drug: Placebo
25 Completed Recombinant Human Relaxin in the Treatment of Diffuse Scleroderma
Condition: Systemic Sclerosis
Intervention: Drug: Relaxin
26 Completed
Has Results
Pulmonary Involvement in Scleroderma: A Clinical Study of the Safety and Efficacy of Mycophenolate Mofetil in Scleroderma Patients With Lung Involvement
Condition: Scleroderma, Systemic
Intervention: Drug: Mycophenolate mofetil
27 Completed
Has Results
High Dose Cyclophosphamide for Treatment of Scleroderma
Condition: Scleroderma
Intervention: Drug: IV Cyclophosphamide
28 Unknown  Effectiveness of UVA1-irradiation in the Treatment of Early Skin Fibrosis in Patients Suffering From Systemic Sclerosis
Conditions: Systemic Scleroderma;   Systemic Sclerosis
Interventions: Radiation: UVA1;   Other: UVA1
29 Terminated Proof of Concept Trial of Gleevec (Imatinib) in Active Diffuse Scleroderma
Condition: Scleroderma
Interventions: Drug: Imatinib mesylate;   Other: Placebo
30 Unknown  Genesis of Scleroderma: Role of Environmental Factors in 100 Patients With Scleroderma and 300 Controls
Condition: Scleroderma
Intervention:
31 Recruiting Divalproex Sodium in the Treatment of the Cutaneous Manifestations of Scleroderma
Conditions: Scleroderma;   Systemic Sclerosis
Intervention: Drug: Divalproex sodium
32 Terminated Treatment of Early Systemic Sclerosis by Bosentan
Condition: Systemic Sclerosis (Scleroderma)
Intervention: Drug: bosentan
33 Recruiting Autologous Stem Cell Systemic Sclerosis Immune Suppression Trial
Condition: Scleroderma
Interventions: Procedure: Cytoxan rATG/Fludarabine/HSCT;   Procedure: Cytoxan rATG/HSCT
34 Recruiting Neuropsychiatric Scleroderma Study: Systematic Evaluation of Neuropsychiatric Involvement in Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention: Other: Magnetic resonance Imaging
35 Completed Scleroderma Lung Study
Conditions: Lung Diseases;   Pulmonary Fibrosis;   Systemic Scleroderma;   Scleroderma, Systemic
Interventions: Drug: cyclophosphamide;   Drug: azathioprine
36 Recruiting Scleroderma Registry & Repository at the Hospital for Special Surgery
Condition: Scleroderma
Intervention:
37 Completed Effectiveness and Safety of Lidocaine for Scleroderma
Condition: Scleroderma
Interventions: Drug: Lidocaine 2% without vessel constrictor;   Other: Placebo - physiological solution 0,9%
38 Unknown  AIMSPRO in Established Diffuse Cutaneous Systemic Sclerosis
Condition: Systemic Sclerosis
Interventions: Drug: Hyperimmune caprine serum;   Drug: Albumin
39 Terminated
Has Results
Placebo Controlled Trial of Bosentan in Scleroderma Patients
Conditions: Systemic Scleroderma;   Pulmonary Hypertension
Interventions: Drug: Bosentan;   Drug: Placebo
40 Recruiting Rituximab in Systemic Sclerosis
Condition: Systemic Sclerosis
Interventions: Drug: Rituximab;   Drug: Placebo (NaCl)

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Indicates status has not been verified in more than two years