22 studies found for:    "Devic disease"
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Rank Status Study
1 Completed
Has Results
An Open Label Study of the Effects of Eculizumab in Neuromyelitis Optica
Conditions: Neuromyelitis Optica;   Devic's Disease
Intervention: Drug: Eculizumab
2 Recruiting A Longitudinal Study of Neuromyelitis Optica and Transverse Myelitis
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder;   Transverse Myelitis;   Optic Neuritis
Intervention:
3 Recruiting Efficacy and Safety of Mitoxantrone in Patients With Refractory Neuromyelitis Optica and Spectrum Disorders
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorders
Intervention: Drug: Mitoxantrone
4 Recruiting Maintenance Plasma Exchange for Neuromyelitis Optica
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder;   Recurrent Idiopathic Longitudinally Extensive Transverse Myelitis
Intervention: Procedure: Plasma exchange (PLEX)
5 Recruiting A Double Blind Trial To Evaluate The Safety And Efficacy Of Eculizumab In Relapsing NMO Patients
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder
Intervention: Drug: Eculizumab
6 Not yet recruiting An Open Label Extension Trial of Eculizumab in Relapsing NMO Patients
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder
Intervention: Biological: eculizumab
7 Recruiting Efficacy of Bevacizumab (Avastin) in Treatment of Acute NMO Exacerbations
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder
Intervention: Drug: Bevacizumab
8 Completed A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic’s Disease)
Conditions: Neuromyelitis Optica;   Myelitis, Transverse;   Demyelinating Autoimmune Diseases, CNS;   Autoimmune Diseases of the Nervous System
Intervention: Drug: Mitoxantrone
9 Recruiting Hematopoietic Stem Cell Transplant in Devic's Disease
Condition: Devic's Disease
Intervention: Procedure: Hematopoietic stem cell transplantation
10 Completed
Has Results
C1-esterase Inhibitor (Cinryze) for Acute Treatment of Neuromyelitis Optica Exacerbation
Condition: Neuromyelitis Optica
Intervention: Drug: C1-esterase inhibitor (Cinryze)
11 Recruiting Autologous Hematopoietic Stem Cell Transplant in Neuromyelitis Optica
Condition: Neuromyelitis Optica (NMO)
Intervention: Procedure: AHSCT
12 Completed Safety and Tolerability of Rituximab in Neuromyelitis Optica
Condition: Neuromyelitis Optica
Intervention: Drug: Rituximab
13 Recruiting Phase II Clinical Trial of NPB-01 in Patients With Anti-aquaporin 4 Antibody Positive Neuromyelitis Optica Spectrum Disorder Not Provided Adequate Effect of Therapy to Steroids Plus Therapy.
Condition: Neuromyelitis Optica Spectrum Disorder
Intervention: Drug: NPB-01
14 Recruiting Pilot Study of alpha1-antitrypsin to Treat Neuromyelitis Optica Relapses
Condition: Neuromyelitis Optica
Interventions: Drug: Alpha1-antitrypsin;   Drug: methylprednisolone
15 Recruiting Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Progressive Multiple Sclerosis and Neuromyelitis Optica
Conditions: Progressive Multiple Sclerosis;   Neuromyelitis Optica.
Intervention: Biological: human umbilical cord mesenchymal stem cells
16 Unknown  Evaluation of Neural Loss in Multiple Sclerosis and Neuromyelitis Optica Using High Resolution Oct
Conditions: Multiple Sclerosis;   Neuromyelitis Optica
Intervention:
17 Recruiting Efficacy and Safety Study as Add-on Therapy of SA237 to Treat NMO and NMOSD
Conditions: Neuromyelitis Optica (NMO);   NMO Spectrum Disorder (NMOSD)
Intervention: Drug: SA237
18 Not yet recruiting Efficacy and Safety Study as Monotherapy of SA237 to Treat NMO and NMOSD
Condition: Neuromyelitis Optica (NMO) and NMO Spectrum Disorder (NMOSD)
Intervention: Drug: SA237
19 Enrolling by invitation Biobank For MS And Other Demyelinating Diseases
Conditions: Multiple Sclerosis;   Transverse Myelitis;   Neuromyelitis Optica;   Acute Disseminated Encephalomyelitis;   Optic Neuritis
Intervention:
20 Unknown  Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous Methylprednisolone
Conditions: Acute Disseminated Encephalomyelitis;   Devic's Syndrome;   Marburg's Variant of Multiple Sclerosis;   Balo's Concentric Sclerosis;   Acute Transverse Myelitis
Intervention: Procedure: Plasma exchange

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Indicates status has not been verified in more than two years