63 studies found for:    "Congenital aplastic anemia"
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Study Details
Participant Details
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Dates
Rank Status Study
1 Completed Tissue Sample Collection From Patients With Fanconi Anemia
Conditions: Fanconi Anemia;   Unspecified Adult Solid Tumor, Protocol Specific;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Other: biologic sample preservation procedure;   Procedure: biopsy
2 Enrolling by invitation Unrelated HSCT in Patients With Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Biological: CD34+ selected cells
3 Completed Oxandrolone for the Treatment of Bone Marrow Aplasia in Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Drug: Oxandrolone
4 Completed Cyclophosphamide in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Fanconi's Anemia
Condition: Fanconi Anemia
Interventions: Drug: cyclophosphamide;   Drug: cyclosporine;   Drug: methotrexate;   Procedure: allogeneic bone marrow transplantation;   Procedure: nonmyeloablative allogeneic hematopoietic stem cell transplantation
5 Active, not recruiting Research Study in Healthy Volunteers or Patients With Fanconi Anemia, Myeloproliferative Disorders, or Myeloma
Conditions: Chronic Myeloproliferative Disorders;   Fanconi Anemia;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic/Myeloproliferative Neoplasms
Interventions: Genetic: microarray analysis;   Genetic: polyacrylamide gel electrophoresis;   Genetic: polymerase chain reaction;   Genetic: protein expression analysis;   Genetic: reverse transcriptase-polymerase chain reaction;   Genetic: western blotting;   Other: chromatography;   Other: high performance liquid chromatography;   Other: immunoenzyme technique
6 Recruiting Cytoxan, Fludara, and Antithymocyte Globulin Conditioning Followed By Stem Cell Transplant in Treating Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Biological: anti-thymocyte globulin;   Drug: cyclophosphamide;   Drug: fludarabine phosphate;   Procedure: hematopoietic stem cell transplantation;   Drug: methylprednisolone;   Drug: filgrastim;   Drug: cyclosporine;   Drug: Mycophenolate Mofetil
7 Recruiting Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Biological: anti-thymocyte globulin;   Biological: filgrastim;   Drug: busulfan;   Drug: cyclophosphamide;   Drug: fludarabine phosphate;   Drug: methylprednisolone;   Biological: Hematopoietic stem cell transplantation
8 Terminated
Has Results
Antibody Conditioning Regimen For Allogeneic Donor Stem Cell Transplantation Of Patients With Fanconi Anemia
Conditions: Fanconi Anemia;   Severe Aplastic Anemia
Interventions: Biological: CAMPATH-1H;   Biological: Anti-CD45;   Drug: Fludarabine;   Procedure: Stem cell infusion
9 Completed Pilot Study of Etanercept (Enbrel) in Children With Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Drug: Etanercept
10 Recruiting Hematopoietic Stem Cell Transplant for Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Device: CliniMACs device
11 Recruiting Quercetin in Children With Fanconi Anemia; a Pilot Study
Condition: Fanconi Anemia
Intervention: Drug: Quercetin (dietary supplement)
12 Terminated Gene Function in Bone Marrow Cells From Patients With Fanconi Anemia and From Healthy Participants
Condition: Fanconi Anemia
Interventions: Genetic: microarray analysis;   Procedure: biopsy
13 Available Use Massive Parallel Sequencing and Exome Capture Technology to Sequence the Exome of Fanconi Anemia Children and Their Patents
Conditions: Fanconi Anemia;   Autosomal or Sex Linked Recessive Genetic Disease;   Bone Marrow Hematopoiesis Failure, Multiple Congenital Abnormalities, and Susceptibility to Neoplastic Diseases.;   Hematopoiesis Maintainance.
Interventions: Genetic: human whole exome;   Genetic: whole genomic
14 Completed Gene Therapy for the Treatment of Fanconi's Anemia Type C
Conditions: Fanconi's Anemia;   Pancytopenia
Intervention: Drug: Transduced CD34+ Cells
15 Unknown  Phase I Pilot Study of CD34 Enriched, Fanconi's Anemia Complementation Group C Gene Transduced Autologous Peripheral Blood Stem Cell Transplantation in Patients With Fanconi's Anemia
Condition: Fanconi's Anemia
Interventions: Drug: filgrastim;   Genetic: Autologous stem cells transduced with FACC retroviral vector;   Procedure: Autologous Stem Cell Transplantation
16 Terminated
Has Results
Stem Cell Transplantation for Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Procedure: Hematopoietic Stem Cell Transplant;   Procedure: Thymic Shielding During Radiation;   Procedure: Total Body Irradiation;   Drug: Cyclophosphamide, Fludarabine
17 Recruiting Gene Therapy for Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Procedure: harvest procedure;   Biological: genetically engineered lymphocyte therapy;   Other: laboratory biomarker analysis
18 Completed Bone Marrow Cell Gene Transfer in Individuals With Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Genetic: Retrovirus Construct
19 Recruiting TBI Dose De-escalation for Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Drug: Cyclophosphamide;   Drug: Fludarabine;   Procedure: Total Body Irradiation;   Procedure: Bone Marrow Transplantation;   Drug: Mycophenolate Mofetil;   Drug: Sirolimus
20 Completed Blood Cell Collection for Future Use in Individuals With Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Procedure: PBSC Collection;   Procedure: Bone Marrow Harvest;   Device: CliniMacs Cell Selection System

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Indicates status has not been verified in more than two years