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37 studies found for:    "Chronic granulomatous disease"

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Rank Status Study
21 Recruiting Non-Invasive Assessment of Atherosclerosis in Patients With CGD and Other Disorders of the Immune System
Conditions: Chronic Granulomatous Disease (CGD);   Atherosclerosis;   Immune Deficiencies;   Inflammatory Bowel Disease
Intervention:
22 Completed Itraconazole for the Prevention of Fungal Infections in Chronic Granulomatous Disease
Condition: Mycoses
Intervention: Drug: itraconazole
23 Completed Diagnostic Effectiveness of Virtual Bronchoscopy
Conditions: Bronchogenic Carcinoma;   Chronic Granulomatous Disease;   Job's Syndrome;   Mycobacterium Infection;   Wegener's Granulomatosis
Intervention: Device: virtual bronchoscopy
24 Recruiting Detection and Characterization of Infections and Infection Susceptibility
Conditions: Immune Disorders;   Chronic Granulomatous Disease;   Genetic Immunological Deficiencies;   Hyperimmunoglobulin-E Recurrent Infection Syndrome;   Recurrent Infections
Intervention:
25 Recruiting Immune Disorder HSCT Protocol
Conditions: Immune Deficiency Disorders:;   Severe Combined Immunodeficiency;   Chronic Granulomatous Disease;   X-linked Aggamaglobulinemia;   Wiskott-Aldrich Syndrome;   Hyper-IgM;   DiGeorge Syndrome;   Chediak-Higashi Syndrome;   Common Variable Immune Deficiency;   Immune Dysregulatory Disorder:;   Hemophagocytic Lymphohistiocytosis;   IPEX;   Autoimmune Lymphoproliferative Syndrome;   X-linked Lymphoproliferative Syndrome
Intervention: Drug: Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan
26 Recruiting Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies
Conditions: Severe Combined Immunodeficiency;   Omenn's Syndrome;   Reticular Dysgenesis;   Wiskott-Aldrich Syndrome;   Bare Lymphocyte Syndrome;   MHC Class II Deficiency;   Common Variable Immunodeficiency;   Chronic Granulomatous Disease;   CD40 Ligand Deficiency;   Hyper IgM Syndrome;   X-linked Lymphoproliferative Disease;   Hemophagocytic Lymphohistiocytosis;   Combined Immune Deficiencies;   Griscelli Syndrome;   Chediak-Higashi Syndrome;   Langerhan's Cell Histiocytosis
Interventions: Drug: Alemtuzumab 0.3 mg;   Drug: Cyclophosphamide;   Drug: Busulfan;   Biological: Stem Cell Transplantation;   Drug: Fludarabine phosphate 40 mg;   Drug: Melphalan;   Drug: Alemtuzumab 0.2 mg;   Drug: Fludarabine phosphate 30 mg;   Drug: MESNA
27 Suspended Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation
Conditions: Thalassemia;   Sickle Cell Disease;   Glanzmann Thrombasthenia;   Wiskott-Aldrich Syndrome;   Chronic-granulomatous Disease;   Severe Congenital Neutropenia;   Leukocyte Adhesion Deficiency;   Schwachman-Diamond Syndrome;   Diamond-Blackfan Anemia;   Fanconi Anemia;   Dyskeratosis-congenita;   Chediak-Higashi Syndrome;   Severe Aplastic Anemia
Intervention: Drug: Alefacept
28 Not yet recruiting Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases
Conditions: Severe Combined Immunodeficiency (SCID);   Immunodeficiency With Predominant T-cell Defect, Unspecified;   Severe Chronic Neutropenia;   Chronic Granulomatous Disease (CGD);   Hyper IgE Syndromes;   Hyper IgM Deficiencies;   Wiskott-Aldrich Syndrome;   Mendelian Susceptibility to Mycobacterial Disease;   Common Variable Immune Deficiency (CVID)
Intervention: Biological: CD3/CD19 negative allogeneic hematopoietic stem cells
29 Recruiting Collection of Lung Fluid and Tissue Samples for Research
Conditions: Mycobacterium Infections, Atypical;   Granulomatous Disease, Chronic;   Job's Syndrome;   Influenza, Human
Intervention:
30 Unknown † Study of Total Body Irradiation and Fludarabine Followed By Allogeneic Peripheral Blood Stem Cell or Bone Marrow Transplantation in Combination With Cyclosporine and Mycophenolate Mofetil in Patients With Inherited Disorders
Conditions: Metabolism, Inborn Errors;   Granulomatous Disease, Chronic
Interventions: Drug: cyclosporine;   Drug: fludarabine;   Drug: mycophenolate mofetil
31 Completed Posaconazole to Treat Invasive Fungal Infections
Conditions: Granulomatous Disease, Chronic;   Job's Syndrome;   Infection
Intervention: Drug: Posaconazole
32 Recruiting Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells
Conditions: Sickle Cell Disease;   Thalassemia;   Anemia;   Granuloma;   Wiskott-Aldrich Syndrome;   Chediak Higashi Syndrome;   Osteopetrosis;   Neutropenia;   Thrombocytopenia;   Hurler Disease;   Niemann-Pick Disease;   Fucosidosis
Intervention: Procedure: Hematopoietic stem cell transplantation
33 Completed Use of Busulfan as Conditioning Agent for a Second Stem Cell Transplant
Conditions: Granulomatous Disease;   Chronic
Intervention: Drug: Busulfan
34 Active, not recruiting Genetic Disorders of Mucociliary Clearance in Nontuberculous Mycobacterial Lung Disease
Conditions: Mycobacteria, Atypical;   Cystic Fibrosis;   Ciliary Disorders;   Pseudohypoaldosteronism;   Bronchiectasis
Intervention:
35 Recruiting Evaluation of Patients With Immune Function Abnormalities
Condition: Immune System Diseases
Intervention:
36 Recruiting Studies of Disorders With Increased Susceptibility to Fungal Infections
Conditions: Primary Immune Deficiency;   Candida;   Autoimmune Polyendocrinopathy Candidiasis Ectodermal;   Chronic Mucocutaneous Candidiasis (CMC);   Fungal Infection
Intervention:
37 Recruiting Treosulfan and Fludarabine Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders
Condition: Nonmalignant Neoplasm
Interventions: Procedure: umbilical cord blood transplantation;   Procedure: peripheral blood stem cell transplantation;   Procedure: allogeneic bone marrow transplantation;   Drug: fludarabine phosphate;   Drug: treosulfan;   Radiation: total-body irradiation;   Drug: tacrolimus;   Drug: methotrexate;   Drug: cyclosporine;   Drug: mycophenolate mofetil;   Genetic: DNA analysis;   Other: laboratory biomarker analysis;   Genetic: cytogenetic analysis;   Biological: anti-thymocyte globulin
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† Indicates status has not been verified in more than two years