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34 studies found for:    "Camurati-Engelmann disease"

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Rank Status Study
1 Completed Angiotensin II Antagonism of TGF-Beta 1
Conditions: Diabetic Nephropathy;   Hypertension
Intervention: Drug: Candesartan
2 Unknown † Prognostic Value of Transforming Growth Factor-Beta 1 in Normal Pressure Hydrocephalus
Condition: Normal Pressure Hydrocephalus
Intervention: Other: CSF collection
3 Recruiting Her2 and TGFBeta CTLs in Treatment of Her2 Positive Malignancy
Condition: HER2 Positive Malignancies
Intervention: Genetic: TGFBeta resistant HER2/EBV-CTLs
4 Completed Safety, Tolerability, and Pharmacokinetics of CAT-192 (Human Anti-TGF-Beta1 Monoclonal Antibody) in Patients With Early Stage Diffuse Systemic Sclerosis
Conditions: Systemic Sclerosis;   Scleroderma
Intervention: Drug: Human Anti-Transforming Growth Factor Beta-1 Monoclonal Antibody
5 Recruiting Safety Study of Injections of Autologous/Allogeneic TGFbeta-resistant LMP2A-specific Cytotoxic T-lymphocytes (CTL)
Conditions: Lymphoma;   Hodgkin's Disease;   Relapse;   Lymphoma, Non-Hodgkin
Intervention: Genetic: TGF-b Resistant LMP2A-Specific Cytotoxic T-Lymphocytes
6 Recruiting TGF-(Beta) and Susceptibility to RSV
Conditions: Respiratory Syncytial Virus;   Asthma
Intervention:
7 Completed Anti-TGF-beta Therapy in Patients With Myelofibrosis
Conditions: Myelofibrosis;   Primary Myelofibrosis;   Post-polycythemia Vera Related Myelofibrosis;   Post-essential Thrombocythemia Related Myelofibrosis
Intervention: Biological: monoclonal antibody to TGF-beta
8 Completed Safety and Tolerability of AP 12009, Administered I.V. in Patients With Advanced Tumors Known to Overproduce TGF-beta-2
Conditions: Pancreatic Neoplasms;   Melanoma;   Colorectal Neoplasms
Intervention: Drug: AP 12009
9 Completed Growth Factor Levels in the Blood of Patients Undergoing Radiation Therapy for Epithelial Cancer
Conditions: Breast Cancer;   Colorectal Cancer;   Head and Neck Cancer;   Lung Cancer;   Prostate Cancer
Interventions: Procedure: venipuncture;   Radiation: radiation therapy
10 Recruiting Fresolimumab In Systemic Sclerosis
Condition: Diffuse Systemic Sclerosis
Intervention: Drug: Fresolimumab
11 Unknown † Radiation Therapy in Treating Women With Invasive Breast Cancer
Condition: Breast Cancer
Interventions: Other: laboratory biomarker analysis;   Procedure: adjuvant therapy;   Radiation: radiation therapy
12 Completed Phase II Study of Lucanix™ in Patients With Stages II-IV Non-Small Cell Lung Cancer
Conditions: Lung Neoplasm;   Carcinoma, Bronchogenic
Intervention: Biological: Lucanix
13 Completed Part 2 of Phase 1 Study of GC1008 to Treat Advanced Melanoma (Part 2 Will Only Accept and Treat Patients With Advanced Malignant Melanoma)
Condition: Renal Cell Carcinoma
Intervention: Drug: Anti-Transforming Growth Factor-beta (GC 1008)
14 Completed Effect of Montelukast on Remodelling Markers in Asthmatic Children
Condition: Asthma
Interventions: Drug: Montelukast;   Drug: placebo
15 Completed Assessment of the Effects of a DPP-4 Inhibitor (Sitagliptin) Januvia on Immune Function in Healthy Individuals
Conditions: Diabetes Mellitus Type 1;   Diabetes Mellitus Type 2
Intervention: Drug: Sitagliptin (Januvia)
16 Completed A Pilot Trial of Tamoxifen and 4-HPR (4-N-Hydroxyphenyl Retinamide) in Persons at High Risk for Developing Breast Cancer
Conditions: Breast Cancer;   Breast Neoplasms
Intervention: Drug: fenretinide
17 Recruiting Genetic Analysis of Familial Keloids
Condition: Keloid
Intervention:
18 Completed
Has Results 		Pirfenidone to Treat Kidney Disease (Focal Segmental Glomerulosclerosis)
Conditions: Fibrosis;   Focal Glomerulosclerosis;   Kidney Failure;   Nephrotic Syndrome;   Proteinuria
Intervention: Drug: Pirfenidone
19 Recruiting Fresolimumab and Radiotherapy in Metastatic Breast Cancer
Condition: Metastatic Breast Cancer
Interventions: Drug: fresolimumab (GC1008);   Radiation: Radiation Therapy
20 Completed The Role of Connective Tissue Growth Factor in the Development of Kidney Disease After Organ Transplantation
Condition: Kidney Transplantation
Intervention:
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† Indicates status has not been verified in more than two years