288 studies found for:    "Brain tumor adult"
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Rank Status Study
1 Active, not recruiting A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas
Conditions: Adult Anaplastic Astrocytoma;   Recurrent Grade III Glioma;   Recurrent Grade IV Glioma;   Adult Anaplastic Oligodendroglioma;   Adult Brain Tumor;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Adult Mixed Glioma;   Recurrent Adult Brain Tumor;   Adult Anaplastic Oligoastrocytoma;   Recurrent High Grade Glioma
Interventions: Drug: flucytosine;   Other: polymerase chain reaction;   Other: immunohistochemistry staining method;   Biological: gene therapy;   Other: pharmacological study;   Other: 3-Tesla magnetic resonance imaging;   Other: laboratory biomarker analysis;   Procedure: therapeutic conventional surgery;   Biological: E. coli CD-expressing genetically modified neural stem cells
2 Completed Tandutinib in Treating Patients With Recurrent or Progressive Glioblastoma
Conditions: Adult Brain Tumor;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Procedure: conventional surgery;   Drug: tandutinib;   Other: pharmacological study;   Other: biopsy
3 Recruiting Viral Therapy in Treating Patients With Recurrent Glioblastoma Multiforme
Conditions: Adult Brain Tumor;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Biological: carcinoembryonic antigen-expressing measles virus;   Procedure: therapeutic conventional surgery;   Other: laboratory biomarker analysis
4 Completed Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas
Conditions: Adult Brain Tumor;   Adult Brain Stem Glioma;   Adult Diffuse Astrocytoma;   Adult Ependymoma;   Adult Grade II Meningioma;   Adult Melanocytic Lesion;   Adult Meningeal Hemangiopericytoma;   Adult Mixed Glioma;   Adult Oligodendroglioma;   Adult Pineal Gland Astrocytoma;   Adult Pineocytoma;   Recurrent Adult Brain Tumor
Interventions: Radiation: proton beam radiation therapy;   Procedure: quality-of-life assessment;   Other: questionnaire administration
5 Terminated
Has Results
Erlotinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma
Condition: Adult Brain Tumors
Intervention: Drug: erlotinib hydrochloride
6 Completed Gliadel Wafer and O6-Benzylguanine in Treating Patients With Recurrent Glioblastoma Multiforme
Condition: Recurrent Adult Brain Tumor
Intervention: Drug: Gliadel wafers in combination with O6-benzylguanine
7 Recruiting NovoTTF-100A With Bevacizumab (Avastin) in Patients With Recurrent Glioblastoma
Conditions: Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Biological: Bevacizumab;   Device: NovoTTF-l00A;   Other: Quality of Life Assessment
8 Recruiting Prevalence of Post-craniotomy Headache in Siriraj Hospital
Conditions: Adult Brain Tumor;   Headache
Intervention:
9 Active, not recruiting Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patients
Conditions: Recurrent Glioblastoma Multiforme;   Malignant Glioma;   Adult Brain Tumor
Interventions: Drug: Vorinostat;   Drug: Bevacizumab
10 Recruiting Light Sedation or Intubated General Anesthesia in Patients With Brain Cancer Undergoing Craniotomy
Condition: Adult Brain Tumor
Interventions: Procedure: Arm I (light sedation);   Procedure: Arm II (intubated general anesthesia);   Other: Arm II (intubated general anesthesia);   Other: Arm I (light sedation)
11 Recruiting 18F-FLT PET/CT in Measuring Cell Proliferation in Patients With Brain Tumors
Condition: Adult Brain Tumor
Interventions: Radiation: fluorine F 18 fluorothymidine;   Procedure: positron emission tomography;   Procedure: computed tomography
12 Recruiting Longitudinal Metabolomic and Epigenetic Profiling of Bodyfluids From Patients With Lung and Brain Cancer Receiving Radiation Therapy
Conditions: Adult Brain Tumor;   Lung Cancer;   Radiation Toxicity
Intervention: Other: laboratory biomarker analysis
13 Completed VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide
Conditions: Adult Anaplastic Astrocytoma;   Adult Anaplastic Oligodendroglioma;   Adult Giant Cell Glioblastoma;   Adult Gliosarcoma;   Adult Mixed Glioma;   Recurrent Adult Brain Tumor
Intervention: Biological: ziv-aflibercept
14 Active, not recruiting Bevacizumab With or Without Trebananib in Treating Patients With Recurrent Brain Tumors
Conditions: Adult Anaplastic Oligodendroglioma;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Adult Oligodendroglioma;   Recurrent Adult Brain Tumor
Interventions: Biological: bevacizumab;   Biological: trebananib;   Other: placebo;   Other: pharmacological study;   Other: laboratory biomarker analysis
15 Completed A Phase I/II Trial of BMS-247550 for Treatment of Patients With Recurrent High-Grade Gliomas
Conditions: Adult Anaplastic Astrocytoma;   Adult Giant Cell Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Drug: ixabepilone;   Other: pharmacological study
16 Completed Sorafenib Combined With Erlotinib, Tipifarnib, or Temsirolimus in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma
Conditions: Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Drug: sorafenib tosylate;   Drug: erlotinib hydrochloride;   Drug: tipifarnib;   Drug: temsirolimus
17 Completed
Has Results
Vorinostat and Bortezomib in Treating Patients With Progressive, Recurrent Glioblastoma Multiforme
Conditions: Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Drug: vorinostat;   Procedure: therapeutic conventional surgery;   Drug: bortezomib
18 Recruiting Carboplatin in Treating Patients With Recurrent High-Grade Gliomas
Conditions: Adult Anaplastic Astrocytoma;   Adult Anaplastic Oligodendroglioma;   Recurrent Adult Brain Tumor
Interventions: Drug: carboplatin;   Procedure: Surgery
19 Not yet recruiting Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas
Conditions: Adult Anaplastic Astrocytoma;   Adult Anaplastic Oligodendroglioma;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Biological: carboxylesterase-expressing allogeneic neural stem cells;   Drug: irinotecan hydrochloride;   Other: laboratory biomarker analysis;   Other: pharmacological study
20 Active, not recruiting Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Recurrent or Progressive Glioblastoma
Conditions: Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Recurrent Adult Brain Tumor
Interventions: Drug: gamma-secretase/Notch signalling pathway inhibitor RO4929097;   Procedure: therapeutic conventional surgery;   Other: pharmacological study;   Other: laboratory biomarker analysis

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Indicates status has not been verified in more than two years