99 studies found for:    "Beta-thalassemia"
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Rank Status Study
21 Unknown  Genetic Factors Affecting the Severity of Beta Thalassemia
Condition: Beta Thalassemia
Intervention:
22 Unknown  Zoledronic Acid for the Prevention of Bone Loss Post-bone Marrow Transplantation for Thalassemia Major Patients
Conditions: Beta-Thalassemia;   Bone Marrow Transplantation
Interventions: Drug: Zoledronic acid;   Drug: Placebo
23 Recruiting Study to Determine the Safety and Tolerability of Sotatercept (ACE-011) in Adults With Beta( β)- Thalassemia.
Conditions: Beta Thalassemia Major;   Beta Thalassemia Intermedia
Interventions: Drug: Dose level 1a;   Drug: Dose level 1b;   Drug: Dose level 2;   Drug: dose level 3;   Drug: dose level 4;   Drug: dose level 5
24 Unknown  Therapeutic Effects of Silymarin in Patients With B-thalassemia Major
Conditions: Beta-thalassemia Major;   Iron Overload
Interventions: Drug: Silymarin (LEGALON);   Drug: Placebo
25 Unknown  Prevalence of Pulmonary Hypertension (PAH) in Patients With Thalassemia
Conditions: Thalassemia Major;   Thalassemia Intermedia;   Pulmonary Arterial Hypertension
Intervention: Other: Physician standard-of-care according to ESC/ERS Guidelines
26 Completed Phase II Study of Arginine Butyrate With or Without Epoetin Alfa in Patients With Thalassemia Intermedia
Condition: Beta-Thalassemia
Interventions: Drug: arginine butyrate;   Drug: epoetin alfa
27 Completed Study of SDMB (2,2 Dimethylbutyrate, Sodium Salt) in Beta Thalassemia Intermedia in Thailand
Condition: Beta Thalassemia Intermedia
Intervention: Drug: sodium 2,2 dimethylbutyrate
28 Completed Assess the Feasibility and Safety of Granulocyte Colony Stimulating Factor (GCSF) Mobilization of CD34+ Hematopoietic Progenitor Cells in Patients With Betathalassemia Major
Conditions: Beta Thalassemia Major;   Congenital Anemias
Intervention: Genetic: GCSF, Central venous line placement, Stem cell Collection (leukapheresis)
29 Unknown  Prevalence Of Microalbuminuria Among Children Suffering From Sickle Cell Nephropathy and Sickle Cell/Beta-Thalassemia
Conditions: Sickle Cell Anemia;   Beta-Thalassemia;   Microalbuminuria
Intervention: Other: No intervention
30 Completed Amlodipine Use in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major
Condition: Thalassemia Major
Intervention: Drug: Amlodipine
31 Completed Perceptions of Thalassemia Major in Singapore: An Exploratory Study of Stigma
Condition: Thalassemia Major
Intervention:
32 Completed Combination Therapy of Hydroxyurea With L-Carnitine and Magnesium Chloride in Thalassemia Intermedia
Condition: β-Thalassemia Intermedia
Interventions: Drug: hydroxyurea;   Drug: L-carnitine and hydroxyurea;   Drug: hydroxyurea and magnesium chloride;   Drug: hydroxyurea,L-carnitine and magnesium chloride
33 Recruiting Post Hematopoietic Stem Cell Transplantation
Condition: Iron Overload After Hematopoietic Stem Cell Transplantation (HSCT) in Patients With Beta-thalassemia Major
Intervention: Drug: ICL670
34 Completed
Has Results
A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.
Conditions: Transfusional Iron Overload;   β-thalassemia Major;   Pediatric Rare Anemia
Intervention: Drug: Deferasirox
35 Completed Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN)
Conditions: Anemia, Cooley's;   Beta-Thalassemia;   Hematologic Diseases;   Thalassemia;   Osteoporosis;   Iron Overload;   Hypertension, Pulmonary
Interventions: Drug: Deferoxamine;   Drug: Deferiprone;   Drug: Arginine;   Drug: Sildenafil;   Drug: Decitabine
36 Completed Monitoring of Erythroid Lineage Specific Chimerism Following Allogeneic Hematopoietic Transplantation for Thalassemia Major
Condition: Thalassemia Major
Intervention:
37 Suspended Treatment of Iron Overload Requiring Chelation Therapy
Conditions: Transfusional Iron Overload;   Iron Overload;   Iron Chelation;   Beta-thalassemia;   Transfusional Hemosiderosis;   Iron Metabolism Disorders;   Metabolic Diseases
Interventions: Drug: SPD602;   Drug: Deferasirox
38 Recruiting Study to Evaluate Efficacy and Safety of S303 Treated Red Blood Cells (RBCs)in Subjects With Thalassemia Major Requiring Chronic RBC Transfusion
Condition: Thalassemia Major
Interventions: Biological: S-303 Treated Red Blood Cells (RBCs);   Biological: Conventional, untreated Red Blood Cells
39 Withdrawn An Open Label Study to Evaluate the Pharmacokinetics, Safety, Tolerability and Efficacy of Deferasirox Administered to Chinese Patients With β-thalassemia Major Aged From 2 to Less Than 6 Years Old
Condition: β-thalassemia Major
Intervention: Drug: Deferasirox
40 Suspended Safety, Efficacy and Pharmacokinetics of an Oral Iron Chelator Given for a Year to Pediatric Patients With Iron Overload
Conditions: Transfusional Iron Overload;   Beta-Thalassemia
Intervention: Drug: SPD602

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Indicates status has not been verified in more than two years