333 studies found for:    "Anaplastic astrocytoma"
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Rank Status Study
21 Completed Histologic Effect/Safety of Pre/Post-Operative IL13-PE38QQR in Recurrent Resectable Supratentorial Malignant Glioma Patients
Conditions: Malignant Glioma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Mixed Oligoastrocytoma;   Malignant Astrocytoma
Interventions: Drug: IL13-PE38QQR;   Procedure: targeted fusion protein therapy;   Procedure: surgery
22 Completed A Study of PD 0332991 in Patients With Recurrent Rb Positive Glioblastoma
Conditions: Glioblastoma;   Gliosarcoma;   Anaplastic Astrocytoma
Intervention: Drug: PD 0332991
23 Not yet recruiting 18F FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly Diagnosed or Recurrent Gliomas
Conditions: Adult Anaplastic Ependymoma;   Adult Anaplastic Oligodendroglioma;   Adult Brain Stem Glioma;   Adult Diffuse Astrocytoma;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Adult Mixed Glioma;   Adult Oligodendroglioma;   Adult Pilocytic Astrocytoma;   Adult Pineal Gland Astrocytoma;   Adult Subependymal Giant Cell Astrocytoma;   Childhood High-grade Cerebellar Astrocytoma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Low-grade Cerebellar Astrocytoma;   Childhood Low-grade Cerebral Astrocytoma;   Recurrent Adult Brain Tumor;   Recurrent Childhood Anaplastic Astrocytoma;   Recurrent Childhood Anaplastic Oligoastrocytoma;   Recurrent Childhood Anaplastic Oligodendroglioma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Diffuse Astrocytoma;   Recurrent Childhood Fibrillary Astrocytoma;   Recurrent Childhood Gemistocytic Astrocytoma;   Recurrent Childhood Giant Cell Glioblastoma;   Recurrent Childhood Glioblastoma;   Recurrent Childhood Gliomatosis Cerebri;   Recurrent Childhood Gliosarcoma;   Recurrent Childhood Oligoastrocytoma;   Recurrent Childhood Oligodendroglioma;   Recurrent Childhood Pilomyxoid Astrocytoma;   Recurrent Childhood Protoplasmic Astrocytoma;   Recurrent Childhood Subependymal Giant Cell Astrocytoma;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma;   Recurrent Childhood Visual Pathway Glioma;   Untreated Childhood Anaplastic Astrocytoma;   Untreated Childhood Anaplastic Oligoastrocytoma;   Untreated Childhood Anaplastic Oligodendroglioma;   Untreated Childhood Brain Stem Glioma;   Untreated Childhood Cerebellar Astrocytoma;   Untreated Childhood Cerebral Astrocytoma;   Untreated Childhood Diffuse Astrocytoma;   Untreated Childhood Fibrillary Astrocytoma;   Untreated Childhood Gemistocytic Astrocytoma;   Untreated Childhood Giant Cell Glioblastoma;   Untreated Childhood Glioblastoma;   Untreated Childhood Gliomatosis Cerebri;   Untreated Childhood Gliosarcoma;   Untreated Childhood Oligoastrocytoma;   Untreated Childhood Oligodendroglioma;   Untreated Childhood Pilomyxoid Astrocytoma;   Untreated Childhood Protoplasmic Astrocytoma;   Untreated Childhood Subependymal Giant Cell Astrocytoma;   Untreated Childhood Visual Pathway and Hypothalamic Glioma;   Untreated Childhood Visual Pathway Glioma
Interventions: Drug: fluorine F 18 fluorodopa;   Procedure: positron emission tomography;   Procedure: computed tomography;   Procedure: magnetic resonance imaging
24 Completed Phase IIb Clinical Trial With TGF-β2 Antisense Compound AP 12009 for Recurrent or Refractory High-grade Glioma
Conditions: Glioblastoma;   Anaplastic Astrocytoma
Interventions: Drug: AP 12009 10 µM;   Drug: AP 12009 80 µM;   Drug: temozolomide or PCV;   Device: Drug delivery system for administration of AP 12009;   Procedure: Placement of Drug Delivery System
25 Completed Ph I Oral Topotecan and Temozolomide for Patients With Malignant Gliomas
Conditions: Glioblastoma;   Gliosarcoma;   Anaplastic Astrocytoma
Intervention: Drug: Oral Topotecan and Temodar
26 Recruiting A Study of a Retroviral Replicating Vector Administered to Subjects With Recurrent Malignant Glioma
Conditions: Glioblastoma;   Anaplastic Astrocytoma;   Anaplastic Oligodendroglioma;   Anaplastic Oligoastrocytoma
Interventions: Biological: Toca 511;   Drug: 5-FC
27 Unknown  Sorafenib in Newly Diagnosed High Grade Glioma
Conditions: Glioblastoma;   Gliosarcoma;   Anaplastic Astrocytoma;   Anaplastic Oligoastrocytoma;   Anaplastic Oligodendroglioma
Intervention: Drug: Sorafenib dose escalation
28 Completed IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma
Conditions: Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Oligoastrocytoma
Interventions: Drug: IL13-PE38QQR;   Procedure: Surgery for placement;   Procedure: Radiation therapy;   Drug: Temozolomide with radiation therapy
29 Recruiting Cellular Immunotherapy Study for Brain Cancer
Conditions: Gliomas;   Anaplastic Astrocytoma;   Anaplastic Oligodendroglioma;   Anaplastic Mixed Glioma;   Glioblastoma Multiforme;   Malignant Meningioma
Intervention: Drug: alloreactive CTL
30 Withdrawn Ph. I Dasatinib/Protracted Temozolomide in Recurrent Malignant Glioma
Conditions: Glioblastoma Multiforme;   Gliosarcoma;   Anaplastic Astrocytoma;   Anaplastic Oligodendroglioma;   Glioma
Intervention: Drug: enzyme-inducing anti-epileptic drugs
31 Recruiting Perifosine and Torisel (Temsirolimus) for Recurrent/Progressive Malignant Gliomas
Conditions: Brain Tumor, Recurrent;   Glioblastoma;   Anaplastic Astrocytoma;   Anaplastic Oligodendroglioma;   Mixed Glioma
Interventions: Procedure: Cytoreductive surgery;   Drug: Perifosine;   Drug: Temsirolimus
32 Recruiting Dendritic Cell Vaccine For Malignant Glioma and Glioblastoma Multiforme in Adult and Pediatric Subjects
Conditions: Malignant Glioma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   High Grade Glioma
Interventions: Biological: Dendritic Cell Vaccine;   Biological: Tumor Lysate;   Other: Imiquimod;   Procedure: Leukapheresis
33 Recruiting Phase I Study of Safety and Immunogenicity of ADU-623
Conditions: Astrocytic Tumors;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Brain Tumor
Interventions: Biological: Cohort 1;   Biological: Cohort 2;   Biological: Cohort 3;   Drug: Antibiotics
34 Completed PH I Addition of Farnesyl Transferase Inhibitor to Temozolomide for Pts w Gr 3 & 4 Malignant Gliomas
Conditions: Gliosarcoma;   Glioblastoma;   Anaplastic Astrocytoma
Intervention: Drug: Temodar and SCH 66336
35 Recruiting AMG 595 First-in-Human in Recurrent Gliomas
Conditions: Advanced Malignant Glioma;   Anaplastic Astrocytomas;   Glioblastoma Multiforme
Intervention: Drug: AMG 595
36 Terminated
Has Results
Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma
Conditions: Brain Tumor;   Anaplastic Astrocytoma;   Anaplastic Ependymoma;   Anaplastic Oligodendroglioma;   Brain Stem Glioma;   Giant Cell Glioblastoma;   Glioblastoma;   Gliosarcoma;   Mixed Glioma
Interventions: Drug: ritonavir;   Drug: lopinavir
37 Completed Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2
Conditions: Anaplastic Astrocytoma;   Anaplastic Ependymoma;   Anaplastic Meningioma;   Anaplastic Oligodendroglioma;   Brain Stem Glioma;   Ependymoblastoma;   Giant Cell Glioblastoma;   Glioblastoma;   Gliosarcoma;   Grade III Meningioma;   Meningeal Hemangiopericytoma;   Mixed Glioma;   Pineal Gland Astrocytoma;   Brain Tumor
Interventions: Biological: therapeutic allogeneic lymphocytes;   Biological: aldesleukin;   Other: laboratory biomarker analysis;   Procedure: positron emission tomography
38 Unknown  Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms
Conditions: Anaplastic Astrocytoma;   Anaplastic Oligodendroglioma;   Mixed Gliomas;   Glioblastoma Multiforme;   Recurrent Brain Tumor
Interventions: Drug: carmustine;   Drug: mercaptopurine;   Drug: streptozocin
39 Unknown  Antineoplaston Therapy in Treating Patients With Anaplastic Astrocytoma
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: antineoplaston A10;   Drug: antineoplaston AS2-1
40 Completed Leflunomide in Treating Patients With Anaplastic Astrocytoma in First Relapse
Condition: Brain and Central Nervous System Tumors
Intervention: Drug: leflunomide

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